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• W2127020103 abstract "Background and Objective Potentially significant associations between metabolic syndrome ( M et S ) and periodontal disease have been reported in recent studies; however, there is a dearth of literature regarding the relationship of M et S with serum antibody levels to periodontal pathogens. The aim of this cross‐sectional study was to investigate the association between M et S and serum antibody to the periodontal pathogen P orphyromonas gingivalis ( P . gingivalis ) in 216 J apanese individuals aged 79 years. Materials and Methods Serum antibody levels to P . gingivalis were measured by enzyme‐linked immunosorbent assay. An elevated serum antibody response was defined as the upper quartile and was considered as the outcome variable. A multivariable logistic regression model was used to evaluate the association of M et S defined by the modified National Cholesterol Education Program Adult Treatment Panel III criteria with an elevated antibody status. Adjustments for gender, income, education, smoking status, dental‐care utilisation patterns and brushing frequency were considered. Results The prevalence of M et S was 22.2% ( n = 48). Study participants with M et S were 2.9 times more likely to have an elevated serum antibody to P . gingivalis (adjusted odds ratio = 2.91, 95% confidence interval = 1.24–6.85) after simultaneous adjustment for other covariates. Conclusion Our findings suggest an independent relationship between M et S and serum antibody levels to P . gingivalis in the J apanese elderly. Additional longitudinal epidemiologic studies with larger, more diversified samples and more complete information are needed to substantiate our findings." @default.
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• W2127020103 date "2014-06-13" @default.
• W2127020103 modified "2023-10-03" @default.
• W2127020103 title "Serum antibody to<i>Porphyromonas gingivalis</i>in metabolic syndrome among an older Japanese population" @default.
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• W2127020103 doi "https://doi.org/10.1111/ger.12135" @default.
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