FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2127042672> ?p ?o ?g. }

• W2127042672 endingPage "S2876" @default.
• W2127042672 startingPage "S2865" @default.
• W2127042672 abstract "Circulating tumour cells are a key challenge in tumour therapy. Numerous approaches are on the way to achieving the elimination of these potential sources of metastasis formation. Antibody-directed magnetic cell sorting is supposed to enrich tumour cells with high selectivity, but low efficiency. The short term application of carboxymethyl dextran (CMD) coated magnetit/maghemit nanoparticles allows the discrimination of tumour cells from leukocytes. In the present work we show that the interaction of CMD nanoparticles is cell-type specific and time dependent. The breast cancer cell line MCF-7 and the CML cell line K-562 are characterized by a rapid and high interaction rate, whereas leukocytes exhibit a decelerated behaviour. The addition of carboxymethyl dextran or glucose stimulated the magnetic labelling of leukocytes. The variation of the degree of substitution of dextran with carboxymethyl groups did not affect the labelling profile of leukocytes and MCF-7 cells. In order to verify the in vitro results, whole blood samples from 13 cancer patients were analysed ex vivo. Incubation of the purified leukocyte fraction with CMD nanoparticles in the presence of low amounts of plasma reduced the overall cell content in the positive fraction. In contrast, the absolute number of residual tumour cells in the positive fraction was 90% of the initial amount." @default.
• W2127042672 created "2016-06-24" @default.
• W2127042672 creator A5053325816 @default.
• W2127042672 creator A5062293424 @default.
• W2127042672 creator A5063234663 @default.
• W2127042672 creator A5064770654 @default.
• W2127042672 date "2006-09-08" @default.
• W2127042672 modified "2023-09-24" @default.
• W2127042672 title "Improvement of the separation of tumour cells from peripheral blood cells using magnetic nanoparticles" @default.
• W2127042672 cites W1591778519 @default.
• W2127042672 cites W1968484150 @default.
• W2127042672 cites W1987168836 @default.
• W2127042672 cites W1989927850 @default.
• W2127042672 cites W1991933103 @default.
• W2127042672 cites W1996139192 @default.
• W2127042672 cites W1996847908 @default.
• W2127042672 cites W2017985531 @default.
• W2127042672 cites W2018952387 @default.
• W2127042672 cites W2020369108 @default.
• W2127042672 cites W2035686038 @default.
• W2127042672 cites W2045380811 @default.
• W2127042672 cites W2073288904 @default.
• W2127042672 cites W2075395060 @default.
• W2127042672 cites W2080637470 @default.
• W2127042672 cites W2084498555 @default.
• W2127042672 cites W2088525015 @default.
• W2127042672 cites W2090340363 @default.
• W2127042672 cites W2100499133 @default.
• W2127042672 cites W2136000176 @default.
• W2127042672 cites W2144837068 @default.
• W2127042672 cites W2153598883 @default.
• W2127042672 cites W2165054637 @default.
• W2127042672 cites W2316721434 @default.
• W2127042672 cites W53893348 @default.
• W2127042672 cites W66824762 @default.
• W2127042672 doi "https://doi.org/10.1088/0953-8984/18/38/s22" @default.
• W2127042672 hasPublicationYear "2006" @default.
• W2127042672 type Work @default.
• W2127042672 sameAs 2127042672 @default.
• W2127042672 citedByCount "15" @default.
• W2127042672 countsByYear W21270426722012 @default.
• W2127042672 countsByYear W21270426722014 @default.
• W2127042672 countsByYear W21270426722015 @default.
• W2127042672 countsByYear W21270426722018 @default.
• W2127042672 countsByYear W21270426722019 @default.
• W2127042672 countsByYear W21270426722023 @default.
• W2127042672 crossrefType "journal-article" @default.
• W2127042672 hasAuthorship W2127042672A5053325816 @default.
• W2127042672 hasAuthorship W2127042672A5062293424 @default.
• W2127042672 hasAuthorship W2127042672A5063234663 @default.
• W2127042672 hasAuthorship W2127042672A5064770654 @default.
• W2127042672 hasConcept C121608353 @default.
• W2127042672 hasConcept C12554922 @default.
• W2127042672 hasConcept C126322002 @default.
• W2127042672 hasConcept C1491633281 @default.
• W2127042672 hasConcept C150903083 @default.
• W2127042672 hasConcept C159654299 @default.
• W2127042672 hasConcept C185592680 @default.
• W2127042672 hasConcept C202751555 @default.
• W2127042672 hasConcept C203014093 @default.
• W2127042672 hasConcept C207001950 @default.
• W2127042672 hasConcept C2777339698 @default.
• W2127042672 hasConcept C2778630268 @default.
• W2127042672 hasConcept C2780523633 @default.
• W2127042672 hasConcept C502942594 @default.
• W2127042672 hasConcept C54355233 @default.
• W2127042672 hasConcept C55493867 @default.
• W2127042672 hasConcept C71924100 @default.
• W2127042672 hasConcept C81885089 @default.
• W2127042672 hasConcept C86803240 @default.
• W2127042672 hasConcept C96232424 @default.
• W2127042672 hasConceptScore W2127042672C121608353 @default.
• W2127042672 hasConceptScore W2127042672C12554922 @default.
• W2127042672 hasConceptScore W2127042672C126322002 @default.
• W2127042672 hasConceptScore W2127042672C1491633281 @default.
• W2127042672 hasConceptScore W2127042672C150903083 @default.
• W2127042672 hasConceptScore W2127042672C159654299 @default.
• W2127042672 hasConceptScore W2127042672C185592680 @default.
• W2127042672 hasConceptScore W2127042672C202751555 @default.
• W2127042672 hasConceptScore W2127042672C203014093 @default.
• W2127042672 hasConceptScore W2127042672C207001950 @default.
• W2127042672 hasConceptScore W2127042672C2777339698 @default.
• W2127042672 hasConceptScore W2127042672C2778630268 @default.
• W2127042672 hasConceptScore W2127042672C2780523633 @default.
• W2127042672 hasConceptScore W2127042672C502942594 @default.
• W2127042672 hasConceptScore W2127042672C54355233 @default.
• W2127042672 hasConceptScore W2127042672C55493867 @default.
• W2127042672 hasConceptScore W2127042672C71924100 @default.
• W2127042672 hasConceptScore W2127042672C81885089 @default.
• W2127042672 hasConceptScore W2127042672C86803240 @default.
• W2127042672 hasConceptScore W2127042672C96232424 @default.
• W2127042672 hasIssue "38" @default.
• W2127042672 hasLocation W21270426721 @default.
• W2127042672 hasOpenAccess W2127042672 @default.
• W2127042672 hasPrimaryLocation W21270426721 @default.
• W2127042672 hasRelatedWork W1856085589 @default.
• W2127042672 hasRelatedWork W1991796607 @default.
• W2127042672 hasRelatedWork W2020692772 @default.

• next