FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2127133037> ?p ?o ?g. }

• W2127133037 endingPage "167" @default.
• W2127133037 startingPage "167" @default.
• W2127133037 abstract "When challenged with allergens and pro-inflammatory agents, such as Aspergillus fumigatus (AF), hay dust solution (HDS) and lipopolysaccharide (LPS), the innate immune response will not only activate the immune system but also increase the amount of pro-inflammatory cytokines in the bronchoalveolar space. The aim of this study was to assess the response of equine alveolar macrophages to different aerosolized challenges and to investigate the differences in this response between horses susceptible or nonsusceptible to recurrent airway obstruction (RAO). Seven susceptible and 5 nonsusceptible horses were challenged with saline, LPS, HDS, or AF, and bronchoalveolar lavage (BAL) cytology, total cell counts, and lung function were assessed. In addition, alveolar macrophages were isolated 6 and 24 hours after challenge, and macrophage mRNA expression of tumor necrosis factor (TNF)-alpha and interleukins (IL) IL-1beta, IL-6, IL-8, and IL-10 were measured by means of real-time (RT) polymerase chain reaction (PCR). There was a significant difference in lung function, neutrophil ratios, and total cell counts in the bronchoalveolar lavage fluid between RAO-susceptible and nonsusceptible horses. In addition, the expression of TNF-alpha, IL-1beta, and IL-8 by alveolar macrophages after challenges were higher in susceptible horses, than in nonsusceptible horses. In contrast, I1-6, considered an anti-inflammatory cytokine, showed a higher expression in nonsusceptible horses 6 hours after inhalation challenge with allergens and pro-inflammatory antigens. These data suggest that the differences between susceptible and nonsusceptible horses to RAO are not only dependent on adaptive immunity but also start with an innate immune response." @default.
• W2127133037 created "2016-06-24" @default.
• W2127133037 creator A5011998876 @default.
• W2127133037 creator A5025638336 @default.
• W2127133037 creator A5041348946 @default.
• W2127133037 creator A5049045463 @default.
• W2127133037 date "2006-01-01" @default.
• W2127133037 modified "2023-10-14" @default.
• W2127133037 title "The Role of Alveolar Macrophages in the Pathogenesis of Recurrent Airway Obstruction in Horses" @default.
• W2127133037 cites W1565355901 @default.
• W2127133037 cites W1966978630 @default.
• W2127133037 cites W1979533406 @default.
• W2127133037 cites W1980220254 @default.
• W2127133037 cites W1982997227 @default.
• W2127133037 cites W1984296249 @default.
• W2127133037 cites W1987150557 @default.
• W2127133037 cites W1991095706 @default.
• W2127133037 cites W1995077996 @default.
• W2127133037 cites W2000830238 @default.
• W2127133037 cites W2004220881 @default.
• W2127133037 cites W2023430605 @default.
• W2127133037 cites W2024537739 @default.
• W2127133037 cites W2025523143 @default.
• W2127133037 cites W2025977330 @default.
• W2127133037 cites W2044327876 @default.
• W2127133037 cites W2052819862 @default.
• W2127133037 cites W2056426013 @default.
• W2127133037 cites W2057288338 @default.
• W2127133037 cites W2062780494 @default.
• W2127133037 cites W2065512020 @default.
• W2127133037 cites W2066092956 @default.
• W2127133037 cites W2071146177 @default.
• W2127133037 cites W2081691949 @default.
• W2127133037 cites W2086668217 @default.
• W2127133037 cites W2092591554 @default.
• W2127133037 cites W2098277628 @default.
• W2127133037 cites W2099880827 @default.
• W2127133037 cites W2100939152 @default.
• W2127133037 cites W2110052216 @default.
• W2127133037 cites W2118945767 @default.
• W2127133037 cites W2123929536 @default.
• W2127133037 cites W2138855338 @default.
• W2127133037 cites W2143897274 @default.
• W2127133037 cites W2163518925 @default.
• W2127133037 cites W2182336116 @default.
• W2127133037 cites W2316477856 @default.
• W2127133037 cites W2437274495 @default.
• W2127133037 doi "https://doi.org/10.1892/0891-6640(2006)20[167:troami]2.0.co;2" @default.
• W2127133037 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16496937" @default.
• W2127133037 hasPublicationYear "2006" @default.
• W2127133037 type Work @default.
• W2127133037 sameAs 2127133037 @default.
• W2127133037 citedByCount "25" @default.
• W2127133037 countsByYear W21271330372013 @default.
• W2127133037 countsByYear W21271330372015 @default.
• W2127133037 countsByYear W21271330372016 @default.
• W2127133037 countsByYear W21271330372018 @default.
• W2127133037 countsByYear W21271330372019 @default.
• W2127133037 countsByYear W21271330372020 @default.
• W2127133037 countsByYear W21271330372021 @default.
• W2127133037 countsByYear W21271330372022 @default.
• W2127133037 countsByYear W21271330372023 @default.
• W2127133037 crossrefType "journal-article" @default.
• W2127133037 hasAuthorship W2127133037A5011998876 @default.
• W2127133037 hasAuthorship W2127133037A5025638336 @default.
• W2127133037 hasAuthorship W2127133037A5041348946 @default.
• W2127133037 hasAuthorship W2127133037A5049045463 @default.
• W2127133037 hasConcept C126322002 @default.
• W2127133037 hasConcept C136449434 @default.
• W2127133037 hasConcept C151730666 @default.
• W2127133037 hasConcept C17991360 @default.
• W2127133037 hasConcept C202751555 @default.
• W2127133037 hasConcept C203014093 @default.
• W2127133037 hasConcept C2777714996 @default.
• W2127133037 hasConcept C2777961210 @default.
• W2127133037 hasConcept C2778012055 @default.
• W2127133037 hasConcept C2778690821 @default.
• W2127133037 hasConcept C2778754761 @default.
• W2127133037 hasConcept C2779244956 @default.
• W2127133037 hasConcept C2780762169 @default.
• W2127133037 hasConcept C55493867 @default.
• W2127133037 hasConcept C71924100 @default.
• W2127133037 hasConcept C86803240 @default.
• W2127133037 hasConcept C8891405 @default.
• W2127133037 hasConceptScore W2127133037C126322002 @default.
• W2127133037 hasConceptScore W2127133037C136449434 @default.
• W2127133037 hasConceptScore W2127133037C151730666 @default.
• W2127133037 hasConceptScore W2127133037C17991360 @default.
• W2127133037 hasConceptScore W2127133037C202751555 @default.
• W2127133037 hasConceptScore W2127133037C203014093 @default.
• W2127133037 hasConceptScore W2127133037C2777714996 @default.
• W2127133037 hasConceptScore W2127133037C2777961210 @default.
• W2127133037 hasConceptScore W2127133037C2778012055 @default.
• W2127133037 hasConceptScore W2127133037C2778690821 @default.
• W2127133037 hasConceptScore W2127133037C2778754761 @default.
• W2127133037 hasConceptScore W2127133037C2779244956 @default.
• W2127133037 hasConceptScore W2127133037C2780762169 @default.
• W2127133037 hasConceptScore W2127133037C55493867 @default.

• next