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• W2127179728 abstract "Z- and Fmoc-l-tetrahydrofuranylglycines have been obtained from l-vinylglycine through dipolar cycloaddition reaction, and its Fmoc derivative has been applied in the synthesis of modified S9 and S10 substrates of HIV-1 protease. These compounds mostly acted as strong inhibitors, rather than substrates, of the protease, probably due to the favourable interactions of the tetrahydrofuranylglycine moiety at the S2 site." @default.
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• W2127179728 date "2002-12-01" @default.
• W2127179728 modified "2023-09-24" @default.
• W2127179728 title "An expedient synthesis of Nα-protected-l-tetrahydrofuranylglycine and its application in the synthesis of novel substrate based inhibitors of HIV-1 protease" @default.
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• W2127179728 doi "https://doi.org/10.1016/s0960-894x(02)00781-3" @default.
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