FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2127185770> ?p ?o ?g. }

• W2127185770 endingPage "450" @default.
• W2127185770 startingPage "442" @default.
• W2127185770 abstract "<h3>Background</h3> Patients with lung cancer are at high risk of venous thromboembolism (VTE), and VTE predicts a poor prognosis. Anticoagulation therefore might be beneficial for these patients. It is not clear whether anticoagulants could improve survival and other outcomes in patients with lung cancer with no indication for anticoagulation. <h3>Methods</h3> We searched the Web of Science, Medline, EMBASE and Cochrane databases for relevant studies. Two reviewers evaluated the studies and extracted data independently. The primary outcomes were 1-year survival and incidence of VTE. Pooled risk ratios (RR) were calculated using control as a reference group and significance was determined by the Z test. <h3>Results</h3> Nine eligible studies with 2185 participants were included. Anticoagulation showed significant improvement in survival at 1 year (RR 1.18, 95% CI 1.06 to 1.32; p=0.004) and at 2 years (RR 1.27, 95% CI 1.04 to 1.56; p=0.02), but not at 6 months. Subgroup analysis showed a survival benefit for patients with small cell lung cancer (SCLC) and those with non-advanced/limited cancer. The incidence of VTE (RR=0.55, 95% CI 0.31 to 0.97; p=0.04) and thromboembolic events (RR=0.48, 95% CI 0.28 to 0.82; p=0.008) was reduced with anticoagulation. Both vitamin K antagonist (VKA) and subcutaneous heparin increased the risk of haemorrhage, but heparin did not increase the incidence of major bleeding. <h3>Conclusions</h3> Anticoagulation showed a survival benefit, especially for those with SCLC and prolonged life expectancy, and reduced the risk of VTE in lung cancer patients with no indication for anticoagulants. Subcutaneous heparin is superior to VKA because of a potentially smaller risk of major bleeding." @default.
• W2127185770 created "2016-06-24" @default.
• W2127185770 creator A5017915107 @default.
• W2127185770 creator A5034762335 @default.
• W2127185770 creator A5062043966 @default.
• W2127185770 creator A5072844265 @default.
• W2127185770 date "2013-01-15" @default.
• W2127185770 modified "2023-10-12" @default.
• W2127185770 title "Efficacy and safety of adjunctive anticoagulation in patients with lung cancer without indication for anticoagulants: a systematic review and meta-analysis" @default.
• W2127185770 cites W155172598 @default.
• W2127185770 cites W1565804212 @default.
• W2127185770 cites W1863488026 @default.
• W2127185770 cites W1895600627 @default.
• W2127185770 cites W1975021346 @default.
• W2127185770 cites W1975757685 @default.
• W2127185770 cites W1976182266 @default.
• W2127185770 cites W1977149417 @default.
• W2127185770 cites W1980067627 @default.
• W2127185770 cites W1984833612 @default.
• W2127185770 cites W1985460122 @default.
• W2127185770 cites W1986215651 @default.
• W2127185770 cites W1996544895 @default.
• W2127185770 cites W2002938738 @default.
• W2127185770 cites W2007086823 @default.
• W2127185770 cites W2019336592 @default.
• W2127185770 cites W2021969922 @default.
• W2127185770 cites W2029754918 @default.
• W2127185770 cites W2031799746 @default.
• W2127185770 cites W2058405988 @default.
• W2127185770 cites W2098500995 @default.
• W2127185770 cites W2103969621 @default.
• W2127185770 cites W2104720408 @default.
• W2127185770 cites W2126930838 @default.
• W2127185770 cites W2138368121 @default.
• W2127185770 cites W2141100626 @default.
• W2127185770 cites W2141269861 @default.
• W2127185770 cites W2142386661 @default.
• W2127185770 cites W2144666882 @default.
• W2127185770 cites W2146823902 @default.
• W2127185770 cites W2150238019 @default.
• W2127185770 cites W2160638301 @default.
• W2127185770 cites W2332736166 @default.
• W2127185770 doi "https://doi.org/10.1136/thoraxjnl-2012-202592" @default.
• W2127185770 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23321607" @default.
• W2127185770 hasPublicationYear "2013" @default.
• W2127185770 type Work @default.
• W2127185770 sameAs 2127185770 @default.
• W2127185770 citedByCount "30" @default.
• W2127185770 countsByYear W21271857702014 @default.
• W2127185770 countsByYear W21271857702015 @default.
• W2127185770 countsByYear W21271857702016 @default.
• W2127185770 countsByYear W21271857702017 @default.
• W2127185770 countsByYear W21271857702018 @default.
• W2127185770 countsByYear W21271857702019 @default.
• W2127185770 countsByYear W21271857702021 @default.
• W2127185770 countsByYear W21271857702023 @default.
• W2127185770 crossrefType "journal-article" @default.
• W2127185770 hasAuthorship W2127185770A5017915107 @default.
• W2127185770 hasAuthorship W2127185770A5034762335 @default.
• W2127185770 hasAuthorship W2127185770A5062043966 @default.
• W2127185770 hasAuthorship W2127185770A5072844265 @default.
• W2127185770 hasBestOaLocation W21271857701 @default.
• W2127185770 hasConcept C120665830 @default.
• W2127185770 hasConcept C121332964 @default.
• W2127185770 hasConcept C126322002 @default.
• W2127185770 hasConcept C141071460 @default.
• W2127185770 hasConcept C187960798 @default.
• W2127185770 hasConcept C2776256026 @default.
• W2127185770 hasConcept C2776301958 @default.
• W2127185770 hasConcept C2776478404 @default.
• W2127185770 hasConcept C2776704044 @default.
• W2127185770 hasConcept C2779161974 @default.
• W2127185770 hasConcept C44249647 @default.
• W2127185770 hasConcept C61511704 @default.
• W2127185770 hasConcept C71924100 @default.
• W2127185770 hasConcept C82789193 @default.
• W2127185770 hasConcept C95190672 @default.
• W2127185770 hasConceptScore W2127185770C120665830 @default.
• W2127185770 hasConceptScore W2127185770C121332964 @default.
• W2127185770 hasConceptScore W2127185770C126322002 @default.
• W2127185770 hasConceptScore W2127185770C141071460 @default.
• W2127185770 hasConceptScore W2127185770C187960798 @default.
• W2127185770 hasConceptScore W2127185770C2776256026 @default.
• W2127185770 hasConceptScore W2127185770C2776301958 @default.
• W2127185770 hasConceptScore W2127185770C2776478404 @default.
• W2127185770 hasConceptScore W2127185770C2776704044 @default.
• W2127185770 hasConceptScore W2127185770C2779161974 @default.
• W2127185770 hasConceptScore W2127185770C44249647 @default.
• W2127185770 hasConceptScore W2127185770C61511704 @default.
• W2127185770 hasConceptScore W2127185770C71924100 @default.
• W2127185770 hasConceptScore W2127185770C82789193 @default.
• W2127185770 hasConceptScore W2127185770C95190672 @default.
• W2127185770 hasIssue "5" @default.
• W2127185770 hasLocation W21271857701 @default.
• W2127185770 hasLocation W21271857702 @default.
• W2127185770 hasLocation W21271857703 @default.
• W2127185770 hasLocation W21271857704 @default.
• W2127185770 hasOpenAccess W2127185770 @default.

• next