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- W2127193558 abstract "Adenovirus infection subverts nucleolar structure and function. B23 is a nucleolar protein present in two isoforms (B23.1 and B23.2) and both isoforms have been identified as stimulatory factors for adenovirus DNA replication. Here, it is demonstrated that the two isoforms of B23, B23.1 and B23.2, interact and co-localize differently with viral DNA replication proteins pTP and DBP in adenovirus-infected cells. Thus, the mechanism by which the two proteins stimulate viral DNA replication is likely to differ. These data also demonstrate the importance of testing both isoforms of B23 for interactions with viral proteins and nucleic acids." @default.
- W2127193558 created "2016-06-24" @default.
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- W2127193558 date "2007-12-01" @default.
- W2127193558 modified "2023-09-24" @default.
- W2127193558 title "Relationship between adenovirus DNA replication proteins and nucleolar proteins B23.1 and B23.2" @default.
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- W2127193558 doi "https://doi.org/10.1099/vir.0.83196-0" @default.
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