FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2127276872> ?p ?o ?g. }

• W2127276872 endingPage "39" @default.
• W2127276872 startingPage "27" @default.
• W2127276872 abstract "The effectiveness of basic fibroblast growth factor and nerve growth factor in preventing the lesion-induced disappearance of septal cholinergic neurons was compared by using a computerized data-acquisition system and a digital brain atlas that yielded quantitative and distributional information. Adult rats were given unilateral partial transections of the fimbria and then received daily intraventricular injection of one of the growth factors for 15 days. Given the high degree of co-localization of nerve growth factor receptors with choline acetyltransferase in these areas, cholinergic neurons were identified by nerve growth factor receptor immunoreactivity. Their locations were plotted in the context of a three-dimensional brain atlas permitting the analysis of relative distributions of cholinergic neurons in control brains and those of animals treated with each growth factor. The cholinergic cell disappearance induced by the partial fimbrial transection was restricted to the medial septal nucleus and the vertical limb of the diagonal band of Broca. Within the affected areas cholinergic cell disappearance increased gradually in severity from anterior to posterior levels of the septal nucleus. Both growth factors prevented the disappearance of cholinergic cell bodies in medial septal nucleus and vertical limb of the diagonal band. In lesioned control animals the unilateral cell disappearance amounted to 53.5% of the number of cholinergic neurons of the unlesioned side. Nerve growth factor and basic fibroblast growth factor reduced this disappearance to 13% and 28%, respectively. The distribution of cholinergic cells was the same in animals treated with each growth factor, suggesting that the two growth factors protect the same population of cholinergic neurons." @default.
• W2127276872 created "2016-06-24" @default.
• W2127276872 creator A5000375997 @default.
• W2127276872 creator A5008985767 @default.
• W2127276872 creator A5013431970 @default.
• W2127276872 creator A5043303570 @default.
• W2127276872 creator A5054270816 @default.
• W2127276872 creator A5086861603 @default.
• W2127276872 date "1991-07-01" @default.
• W2127276872 modified "2023-09-23" @default.
• W2127276872 title "Use of a digital brain atlas to compare the distribution of NGF- and bFGF-protected cholinergic neurons" @default.
• W2127276872 cites W1500220781 @default.
• W2127276872 cites W1565785673 @default.
• W2127276872 cites W1590974871 @default.
• W2127276872 cites W1609471181 @default.
• W2127276872 cites W1898295630 @default.
• W2127276872 cites W1972139650 @default.
• W2127276872 cites W1973531344 @default.
• W2127276872 cites W1975972443 @default.
• W2127276872 cites W1977311938 @default.
• W2127276872 cites W1981919520 @default.
• W2127276872 cites W1983465575 @default.
• W2127276872 cites W1986508730 @default.
• W2127276872 cites W1987091321 @default.
• W2127276872 cites W1988176673 @default.
• W2127276872 cites W1991152935 @default.
• W2127276872 cites W1994385474 @default.
• W2127276872 cites W1998733248 @default.
• W2127276872 cites W2001382455 @default.
• W2127276872 cites W2004045063 @default.
• W2127276872 cites W2009078449 @default.
• W2127276872 cites W2011839234 @default.
• W2127276872 cites W2018434736 @default.
• W2127276872 cites W2020771907 @default.
• W2127276872 cites W2021092333 @default.
• W2127276872 cites W2022599922 @default.
• W2127276872 cites W2022644207 @default.
• W2127276872 cites W2022752214 @default.
• W2127276872 cites W2022908085 @default.
• W2127276872 cites W2024422266 @default.
• W2127276872 cites W2026624422 @default.
• W2127276872 cites W2027399729 @default.
• W2127276872 cites W2033603470 @default.
• W2127276872 cites W2035471834 @default.
• W2127276872 cites W2041544466 @default.
• W2127276872 cites W2043421056 @default.
• W2127276872 cites W2045776001 @default.
• W2127276872 cites W2048751568 @default.
• W2127276872 cites W2048754703 @default.
• W2127276872 cites W2050551267 @default.
• W2127276872 cites W2051485994 @default.
• W2127276872 cites W2054262036 @default.
• W2127276872 cites W2054961876 @default.
• W2127276872 cites W2064659680 @default.
• W2127276872 cites W2064739683 @default.
• W2127276872 cites W2064793866 @default.
• W2127276872 cites W2068371699 @default.
• W2127276872 cites W2069095254 @default.
• W2127276872 cites W2071284923 @default.
• W2127276872 cites W2074785038 @default.
• W2127276872 cites W2084351892 @default.
• W2127276872 cites W2091011317 @default.
• W2127276872 cites W2128378551 @default.
• W2127276872 cites W2143158156 @default.
• W2127276872 cites W2165609315 @default.
• W2127276872 cites W2170633533 @default.
• W2127276872 cites W88851328 @default.
• W2127276872 doi "https://doi.org/10.1002/cne.903090104" @default.
• W2127276872 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1654343" @default.
• W2127276872 hasPublicationYear "1991" @default.
• W2127276872 type Work @default.
• W2127276872 sameAs 2127276872 @default.
• W2127276872 citedByCount "17" @default.
• W2127276872 crossrefType "journal-article" @default.
• W2127276872 hasAuthorship W2127276872A5000375997 @default.
• W2127276872 hasAuthorship W2127276872A5008985767 @default.
• W2127276872 hasAuthorship W2127276872A5013431970 @default.
• W2127276872 hasAuthorship W2127276872A5043303570 @default.
• W2127276872 hasAuthorship W2127276872A5054270816 @default.
• W2127276872 hasAuthorship W2127276872A5086861603 @default.
• W2127276872 hasConcept C104966671 @default.
• W2127276872 hasConcept C105702510 @default.
• W2127276872 hasConcept C126322002 @default.
• W2127276872 hasConcept C134018914 @default.
• W2127276872 hasConcept C169760540 @default.
• W2127276872 hasConcept C170493617 @default.
• W2127276872 hasConcept C198399640 @default.
• W2127276872 hasConcept C22885893 @default.
• W2127276872 hasConcept C2775960820 @default.
• W2127276872 hasConcept C2777587049 @default.
• W2127276872 hasConcept C2777705664 @default.
• W2127276872 hasConcept C2778423431 @default.
• W2127276872 hasConcept C2780723820 @default.
• W2127276872 hasConcept C71924100 @default.
• W2127276872 hasConcept C86803240 @default.
• W2127276872 hasConceptScore W2127276872C104966671 @default.
• W2127276872 hasConceptScore W2127276872C105702510 @default.
• W2127276872 hasConceptScore W2127276872C126322002 @default.

• next