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- W2127288545 abstract "Introduction Experimental observations have reported modulation of cortical oscillations as phases of high synchronization (waxing) followed by periods of reduced synchronization (waning) [1-3]. Although the phenomenon is present in almost all frequency bands, it is still not understood how this is driven. Here we study whether this phenomenon can occur in a network of inhibitory (I) and excitatory (E) cells and what effect external inputs have. Methods Using NEURON, we model a network of Ne excitatory and Ni inhibitory cells such that Ne/Ni = 4. The cells have a single compartment, and include passive channels and voltage dependent Na+, K+ channels. Synaptic connections are random, projecting GABA synapses from I to I and I to E cells and AMPA synapses from E to E and E to I cells. To stimulate the network, each cell receives a baseline of current and a stream of spikes delivered at random intervals across the simulated period. from Eighteenth Annual Computational Neuroscience Meeting: CNS*2009 Berlin, Germany. 18–23 July 2009" @default.
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- W2127288545 date "2009-07-13" @default.
- W2127288545 modified "2023-10-14" @default.
- W2127288545 title "Influence of external input on waxing and waning of neuronal network oscillations" @default.
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- W2127288545 doi "https://doi.org/10.1186/1471-2202-10-s1-p257" @default.
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