FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2127296031> ?p ?o ?g. }

• W2127296031 endingPage "497" @default.
• W2127296031 startingPage "492" @default.
• W2127296031 abstract "BACKGROUND Telomerase activity (TA) has been detected in most malignant neoplasms, including thyroid carcinomas. The authors studied the utility of TA detection as an ancillary tool to thyroid fine-needle aspiration (FNA) for patients with nonconclusive cytologic diagnoses. METHODS Material obtained by FNA from palpable thyroid nodules in 167 consecutive patients was processed for conventional cytologic studies and simultaneously for TA study. Another 8 patients were excluded from TA because of the presence of lymphocytes. All patients with negative results cases were followed for > 1 year, and those who had tumors that were suspicious or positive by FNA or TA underwent resection for pathologic study of nodules. TA was analyzed by telomere repeat amplification protocol-polymerase chain reaction analysis. RESULTS After excluding 20 patients because of insufficient material for cytologic study, 120 patients had negative results for malignant cells in cytology material, and the remaining 27 patients had results that were either suspicious (n = 21 patients) or positive (n = 6 patients). Histopathologic confirmation was obtained in 23 patients, including 18 with suspicious cytology (1 with scanty material) and 5 with positive FNA. The histopathologic diagnoses were nodular hyperplasia in 5 patients, follicular adenoma in 3 patients, papillary carcinoma in 11 patients, follicular carcinoma in 1 patient, medullary carcinoma in 2 patients, and lymphoma in 1 patient. TA was detected in 6 of 18 histologically confirmed thyroid neoplasms (1 of 3 follicular adenomas, 3 of 11 papillary carcinomas, 0 of 1 follicular carcinoma, 1 of 2 medullary carcinomas, and 1 of 1 lymphoma), including 1 neoplasm with scanty atypical cells. CONCLUSIONS The detection of TA helped to confirm neoplasia in 6 of 23 suspicious thyroid nodules. Although it was less sensitive than FNA, TA specificity was 100% for neoplasia and 87.5% for malignancy. The sensitivity of thyroid FNA increased with the use of TA detection when cytology was nonconclusive for malignancy. Cancer (Cancer Cytopathol) 2005. © 2005 American Cancer Society." @default.
• W2127296031 created "2016-06-24" @default.
• W2127296031 creator A5060559093 @default.
• W2127296031 creator A5070683494 @default.
• W2127296031 date "2005-08-15" @default.
• W2127296031 modified "2023-10-14" @default.
• W2127296031 title "Telomerase activity in “suspicious” thyroid cytology" @default.
• W2127296031 cites W1517051009 @default.
• W2127296031 cites W1795008313 @default.
• W2127296031 cites W1963511551 @default.
• W2127296031 cites W1965536769 @default.
• W2127296031 cites W1987313324 @default.
• W2127296031 cites W1989243569 @default.
• W2127296031 cites W1992430278 @default.
• W2127296031 cites W2000971601 @default.
• W2127296031 cites W2010480108 @default.
• W2127296031 cites W2011562398 @default.
• W2127296031 cites W2013364403 @default.
• W2127296031 cites W2035013087 @default.
• W2127296031 cites W2035453768 @default.
• W2127296031 cites W2037474090 @default.
• W2127296031 cites W2042936521 @default.
• W2127296031 cites W2062086731 @default.
• W2127296031 cites W2063480569 @default.
• W2127296031 cites W2083741208 @default.
• W2127296031 cites W2093142286 @default.
• W2127296031 cites W2115286652 @default.
• W2127296031 cites W2116413869 @default.
• W2127296031 cites W2118510888 @default.
• W2127296031 cites W2121463923 @default.
• W2127296031 cites W2130388017 @default.
• W2127296031 cites W2131495156 @default.
• W2127296031 cites W2160591850 @default.
• W2127296031 cites W2163203082 @default.
• W2127296031 cites W2168402896 @default.
• W2127296031 cites W2278288997 @default.
• W2127296031 cites W2314625370 @default.
• W2127296031 cites W2323750964 @default.
• W2127296031 cites W4242558176 @default.
• W2127296031 cites W4254759378 @default.
• W2127296031 doi "https://doi.org/10.1002/cncr.21380" @default.
• W2127296031 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16104043" @default.
• W2127296031 hasPublicationYear "2005" @default.
• W2127296031 type Work @default.
• W2127296031 sameAs 2127296031 @default.
• W2127296031 citedByCount "22" @default.
• W2127296031 countsByYear W21272960312012 @default.
• W2127296031 countsByYear W21272960312013 @default.
• W2127296031 countsByYear W21272960312015 @default.
• W2127296031 countsByYear W21272960312022 @default.
• W2127296031 crossrefType "journal-article" @default.
• W2127296031 hasAuthorship W2127296031A5060559093 @default.
• W2127296031 hasAuthorship W2127296031A5070683494 @default.
• W2127296031 hasBestOaLocation W21272960311 @default.
• W2127296031 hasConcept C126322002 @default.
• W2127296031 hasConcept C142724271 @default.
• W2127296031 hasConcept C18823058 @default.
• W2127296031 hasConcept C2775934546 @default.
• W2127296031 hasConcept C2776170712 @default.
• W2127296031 hasConcept C2776667971 @default.
• W2127296031 hasConcept C2777428134 @default.
• W2127296031 hasConcept C2777546739 @default.
• W2127296031 hasConcept C2778654104 @default.
• W2127296031 hasConcept C2779022025 @default.
• W2127296031 hasConcept C2781283455 @default.
• W2127296031 hasConcept C2993294228 @default.
• W2127296031 hasConcept C526584372 @default.
• W2127296031 hasConcept C71924100 @default.
• W2127296031 hasConceptScore W2127296031C126322002 @default.
• W2127296031 hasConceptScore W2127296031C142724271 @default.
• W2127296031 hasConceptScore W2127296031C18823058 @default.
• W2127296031 hasConceptScore W2127296031C2775934546 @default.
• W2127296031 hasConceptScore W2127296031C2776170712 @default.
• W2127296031 hasConceptScore W2127296031C2776667971 @default.
• W2127296031 hasConceptScore W2127296031C2777428134 @default.
• W2127296031 hasConceptScore W2127296031C2777546739 @default.
• W2127296031 hasConceptScore W2127296031C2778654104 @default.
• W2127296031 hasConceptScore W2127296031C2779022025 @default.
• W2127296031 hasConceptScore W2127296031C2781283455 @default.
• W2127296031 hasConceptScore W2127296031C2993294228 @default.
• W2127296031 hasConceptScore W2127296031C526584372 @default.
• W2127296031 hasConceptScore W2127296031C71924100 @default.
• W2127296031 hasIssue "6" @default.
• W2127296031 hasLocation W21272960311 @default.
• W2127296031 hasLocation W21272960312 @default.
• W2127296031 hasOpenAccess W2127296031 @default.
• W2127296031 hasPrimaryLocation W21272960311 @default.
• W2127296031 hasRelatedWork W2041761228 @default.
• W2127296031 hasRelatedWork W2143285762 @default.
• W2127296031 hasRelatedWork W2177516579 @default.
• W2127296031 hasRelatedWork W2417362407 @default.
• W2127296031 hasRelatedWork W2465913558 @default.
• W2127296031 hasRelatedWork W3037279187 @default.
• W2127296031 hasRelatedWork W4306825773 @default.
• W2127296031 hasRelatedWork W4321003279 @default.
• W2127296031 hasRelatedWork W4363650319 @default.
• W2127296031 hasRelatedWork W2594809463 @default.
• W2127296031 hasVolume "105" @default.

• next