Matches in SemOpenAlex for { <https://semopenalex.org/work/W2127296490> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2127296490 endingPage "S25" @default.
- W2127296490 startingPage "S20" @default.
- W2127296490 abstract "Breast cancer is the most common cancer and the second greatest cause of cancer-related death among women in the United States. Capecitabine is a selectively tumor-activated fluoropyrimidine carbamate that is converted to 5-fluorouracil by the sequential activity of these enzymes, the final of which is thymidine phosphorylase, which is overexpressed in many human cancers. Capecitabine as a single agent and in combination with other drugs is efficacious in previously treated and untreated metastatic breast cancer (MBC). The integration of capecitabine, either as a single agent or in combination with docetaxel, into adjuvant breast cancer therapy is justified due to its high antitumor activity in previously treated and untreated MBC, its tolerability, lack of cross-resistance with the anthracyclines and taxanes, and because combined docetaxel/capecitabine improves the overall survival of patients with MBC. Capecitabine is being evaluated as preoperative therapy in patients with operable breast cancer, as adjuvant therapy in patients with high-risk node-negative or node-positive disease, and as oral single-agent therapy in women > or = 65 years of age. This article is an overview of published studies of capecitabine in MBC and the studies that are planned or have been proposed to evaluate capecitabine as adjuvant therapy for breast cancer." @default.
- W2127296490 created "2016-06-24" @default.
- W2127296490 creator A5071432873 @default.
- W2127296490 date "2003-04-01" @default.
- W2127296490 modified "2023-09-23" @default.
- W2127296490 title "The Evolving Role of Capecitabine in Breast Cancer" @default.
- W2127296490 cites W1760955494 @default.
- W2127296490 cites W1811085086 @default.
- W2127296490 cites W1843618725 @default.
- W2127296490 cites W1939003096 @default.
- W2127296490 cites W1981486175 @default.
- W2127296490 cites W1982182115 @default.
- W2127296490 cites W1988674313 @default.
- W2127296490 cites W2044970916 @default.
- W2127296490 cites W2052953339 @default.
- W2127296490 cites W2099658604 @default.
- W2127296490 cites W2109694492 @default.
- W2127296490 cites W2123732467 @default.
- W2127296490 cites W2131770017 @default.
- W2127296490 cites W2137194656 @default.
- W2127296490 cites W2141393790 @default.
- W2127296490 cites W2164774797 @default.
- W2127296490 cites W2169764884 @default.
- W2127296490 cites W2228069427 @default.
- W2127296490 cites W2259233362 @default.
- W2127296490 cites W4248121975 @default.
- W2127296490 doi "https://doi.org/10.3816/cbc.2003.s.011" @default.
- W2127296490 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12756075" @default.
- W2127296490 hasPublicationYear "2003" @default.
- W2127296490 type Work @default.
- W2127296490 sameAs 2127296490 @default.
- W2127296490 citedByCount "19" @default.
- W2127296490 countsByYear W21272964902012 @default.
- W2127296490 countsByYear W21272964902021 @default.
- W2127296490 crossrefType "journal-article" @default.
- W2127296490 hasAuthorship W2127296490A5071432873 @default.
- W2127296490 hasConcept C121608353 @default.
- W2127296490 hasConcept C126322002 @default.
- W2127296490 hasConcept C143998085 @default.
- W2127296490 hasConcept C197934379 @default.
- W2127296490 hasConcept C2775930923 @default.
- W2127296490 hasConcept C2776735402 @default.
- W2127296490 hasConcept C2777909004 @default.
- W2127296490 hasConcept C2777982462 @default.
- W2127296490 hasConcept C2778375690 @default.
- W2127296490 hasConcept C2780456651 @default.
- W2127296490 hasConcept C2781190966 @default.
- W2127296490 hasConcept C526805850 @default.
- W2127296490 hasConcept C530470458 @default.
- W2127296490 hasConcept C71924100 @default.
- W2127296490 hasConceptScore W2127296490C121608353 @default.
- W2127296490 hasConceptScore W2127296490C126322002 @default.
- W2127296490 hasConceptScore W2127296490C143998085 @default.
- W2127296490 hasConceptScore W2127296490C197934379 @default.
- W2127296490 hasConceptScore W2127296490C2775930923 @default.
- W2127296490 hasConceptScore W2127296490C2776735402 @default.
- W2127296490 hasConceptScore W2127296490C2777909004 @default.
- W2127296490 hasConceptScore W2127296490C2777982462 @default.
- W2127296490 hasConceptScore W2127296490C2778375690 @default.
- W2127296490 hasConceptScore W2127296490C2780456651 @default.
- W2127296490 hasConceptScore W2127296490C2781190966 @default.
- W2127296490 hasConceptScore W2127296490C526805850 @default.
- W2127296490 hasConceptScore W2127296490C530470458 @default.
- W2127296490 hasConceptScore W2127296490C71924100 @default.
- W2127296490 hasLocation W21272964901 @default.
- W2127296490 hasLocation W21272964902 @default.
- W2127296490 hasOpenAccess W2127296490 @default.
- W2127296490 hasPrimaryLocation W21272964901 @default.
- W2127296490 hasRelatedWork W1972397705 @default.
- W2127296490 hasRelatedWork W2001477191 @default.
- W2127296490 hasRelatedWork W2058292467 @default.
- W2127296490 hasRelatedWork W2069882111 @default.
- W2127296490 hasRelatedWork W2266510244 @default.
- W2127296490 hasRelatedWork W2439738364 @default.
- W2127296490 hasRelatedWork W2737206118 @default.
- W2127296490 hasRelatedWork W4252495345 @default.
- W2127296490 hasRelatedWork W4253360580 @default.
- W2127296490 hasRelatedWork W4367362646 @default.
- W2127296490 hasVolume "4" @default.
- W2127296490 isParatext "false" @default.
- W2127296490 isRetracted "false" @default.
- W2127296490 magId "2127296490" @default.
- W2127296490 workType "article" @default.