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• W2127323698 abstract "Members of the septin family of proteins act as organizational scaffolds in areas of cell division and new growth in a variety of organisms. Herein, we show that in the filamentous fungusAspergillus nidulans, the septin AspB is important for cellular division, branching, and conidiation both pre- and postmitotically. AspB localizes postmitotically to the septation site with an underlying polarity that is evident as cytokinesis progresses. This localization at the septation site is dependent on actin and occurs before the cross-wall is visible. AspB localizes premitotically as a ring at sites of branching and secondary germ tube emergence. It is the only known branch site marker. In addition, AspB is found at several stages during the development of the asexual reproductive structure, the conidiophore. It localizes transiently to the vesicle/metula and metula/phialide interfaces, and persistently to the phialide/conidiospore interface. A temperature-sensitive mutant of AspB shows phenotypic abnormalities, including irregular septa, high numbers of branches, and immature asexual reproductive structures." @default.
• W2127323698 created "2016-06-24" @default.
• W2127323698 creator A5002211873 @default.
• W2127323698 creator A5043671404 @default.
• W2127323698 date "2002-01-01" @default.
• W2127323698 modified "2023-10-18" @default.
• W2127323698 title "<i>Aspergillus nidulans</i>Septin AspB Plays Pre- and Postmitotic Roles in Septum, Branch, and Conidiophore Development" @default.
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• W2127323698 doi "https://doi.org/10.1091/mbc.01-06-0312" @default.
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