FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2127355280> ?p ?o ?g. }

• W2127355280 endingPage "5114" @default.
• W2127355280 startingPage "5105" @default.
• W2127355280 abstract "Muscle, motor unit and muscle fibre type-specific differences in force-generating capacity have been investigated for many years, but there is still no consensus regarding specific differences between slow- and fast-twitch muscles, motor units or muscle fibres. This is probably related to a number of different confounding factors disguising the function of the molecular motor protein myosin. We have therefore studied the force-generating capacity of specific myosin isoforms or combination of isoforms extracted from short single human muscle fibre segments in a modified single fibre myosin in vitro motility assay, in which an internal load (actin-binding protein) was added in different concentrations to evaluate the force-generating capacity. The force indices were the x-axis intercept and the slope of the relationship between the fraction of moving filaments and the α-actinin concentration. The force-generating capacity of the β/slow myosin isoform (type I) was weaker (P < 0.05) than the fast myosin isoform (type II), but the force-generating capacity of the different human fast myosin isoforms types IIa and IIx or a combination of both (IIax) were indistinguishable. A single fibre in vitro motility assay for both speed and force of specific myosin isoforms is described and used to measure the difference in force-generating capacity between fast and slow human myosin isoforms. The assay is proposed as a useful tool for clinical studies on the effects on muscle function of specific mutations or post-translational modifications of myosin." @default.
• W2127355280 created "2016-06-24" @default.
• W2127355280 creator A5059674225 @default.
• W2127355280 creator A5082877207 @default.
• W2127355280 date "2010-12-15" @default.
• W2127355280 modified "2023-10-16" @default.
• W2127355280 title "Force-generating capacity of human myosin isoforms extracted from single muscle fibre segments" @default.
• W2127355280 cites W126479960 @default.
• W2127355280 cites W1504054464 @default.
• W2127355280 cites W1515092449 @default.
• W2127355280 cites W1565291379 @default.
• W2127355280 cites W1573366176 @default.
• W2127355280 cites W1966830850 @default.
• W2127355280 cites W1969773420 @default.
• W2127355280 cites W1970900771 @default.
• W2127355280 cites W1983407178 @default.
• W2127355280 cites W1985710170 @default.
• W2127355280 cites W1992036272 @default.
• W2127355280 cites W1994428227 @default.
• W2127355280 cites W2008972088 @default.
• W2127355280 cites W2010762643 @default.
• W2127355280 cites W2014203816 @default.
• W2127355280 cites W2017071770 @default.
• W2127355280 cites W2017488454 @default.
• W2127355280 cites W2020358612 @default.
• W2127355280 cites W2030547704 @default.
• W2127355280 cites W2031987093 @default.
• W2127355280 cites W2032127615 @default.
• W2127355280 cites W2036540440 @default.
• W2127355280 cites W2044791038 @default.
• W2127355280 cites W2046033413 @default.
• W2127355280 cites W2049674222 @default.
• W2127355280 cites W2057276491 @default.
• W2127355280 cites W2058497997 @default.
• W2127355280 cites W2059158601 @default.
• W2127355280 cites W2061131459 @default.
• W2127355280 cites W2063432279 @default.
• W2127355280 cites W206708297 @default.
• W2127355280 cites W2074069675 @default.
• W2127355280 cites W2078623120 @default.
• W2127355280 cites W2085052964 @default.
• W2127355280 cites W2107181694 @default.
• W2127355280 cites W2119770490 @default.
• W2127355280 cites W2140933502 @default.
• W2127355280 cites W2140994672 @default.
• W2127355280 cites W2142693293 @default.
• W2127355280 cites W2147745178 @default.
• W2127355280 cites W2151552361 @default.
• W2127355280 cites W2160719507 @default.
• W2127355280 cites W2170565604 @default.
• W2127355280 cites W2213965861 @default.
• W2127355280 cites W2300568794 @default.
• W2127355280 cites W2413432844 @default.
• W2127355280 cites W261445698 @default.
• W2127355280 cites W296898222 @default.
• W2127355280 doi "https://doi.org/10.1113/jphysiol.2010.199067" @default.
• W2127355280 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3036200" @default.
• W2127355280 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20974679" @default.
• W2127355280 hasPublicationYear "2010" @default.
• W2127355280 type Work @default.
• W2127355280 sameAs 2127355280 @default.
• W2127355280 citedByCount "32" @default.
• W2127355280 countsByYear W21273552802012 @default.
• W2127355280 countsByYear W21273552802013 @default.
• W2127355280 countsByYear W21273552802014 @default.
• W2127355280 countsByYear W21273552802015 @default.
• W2127355280 countsByYear W21273552802016 @default.
• W2127355280 countsByYear W21273552802017 @default.
• W2127355280 countsByYear W21273552802019 @default.
• W2127355280 countsByYear W21273552802020 @default.
• W2127355280 countsByYear W21273552802021 @default.
• W2127355280 countsByYear W21273552802022 @default.
• W2127355280 countsByYear W21273552802023 @default.
• W2127355280 crossrefType "journal-article" @default.
• W2127355280 hasAuthorship W2127355280A5059674225 @default.
• W2127355280 hasAuthorship W2127355280A5082877207 @default.
• W2127355280 hasBestOaLocation W21273552802 @default.
• W2127355280 hasConcept C104317684 @default.
• W2127355280 hasConcept C105702510 @default.
• W2127355280 hasConcept C12554922 @default.
• W2127355280 hasConcept C125705527 @default.
• W2127355280 hasConcept C15954220 @default.
• W2127355280 hasConcept C160408235 @default.
• W2127355280 hasConcept C185592680 @default.
• W2127355280 hasConcept C18923293 @default.
• W2127355280 hasConcept C2776050358 @default.
• W2127355280 hasConcept C53345823 @default.
• W2127355280 hasConcept C55493867 @default.
• W2127355280 hasConcept C6997183 @default.
• W2127355280 hasConcept C74581901 @default.
• W2127355280 hasConcept C8035138 @default.
• W2127355280 hasConcept C86803240 @default.
• W2127355280 hasConceptScore W2127355280C104317684 @default.
• W2127355280 hasConceptScore W2127355280C105702510 @default.
• W2127355280 hasConceptScore W2127355280C12554922 @default.
• W2127355280 hasConceptScore W2127355280C125705527 @default.
• W2127355280 hasConceptScore W2127355280C15954220 @default.
• W2127355280 hasConceptScore W2127355280C160408235 @default.

• next