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• W2127471192 endingPage "431" @default.
• W2127471192 startingPage "425" @default.
• W2127471192 abstract "Abstract It is generally accepted that the purine nucleoside, adenosine, plays a neuromodulatory role in the central nervous system (CNS) (Daly et al., 1981; Phillis ' Wu, 1983; Williams, 1986; Williams, 1987; Snyder, 1985). Adenosine is thought to exert its primary effects presynaptically, by inhibiting the release of neurotransmitters including ³-aminobutyric acid (GABA) and acetylcholine (ACh) (Phillis ' Barraco, 1985; Proctor ' Dunwiddie, 1987). In mammalian retina, cell bodies that are strongly labeled for adenosine-like immunoreactivity (ALIR) have been localized to the ganglion cell layer (GCL) (Braas et al., 1987; Blazynski et al., 1989). Rabbit retinal cells that are labeled by markers for both ACh and GABA are located in the GCL and inner nuclear layer (INL) (Tauchi ' Masland, 1984; Vaney ' Young, 1988 b ; Brecha et al., 1988). It is now demonstrated in the rabbit retina that approximately 50% of the cells labeled for ALIR within the GCL represent true ganglion cells, with the remainder presumed to be displaced cholinergic amacrine cells (DAPI accumulating). In addition, some of these same cells also demonstrate immunoreactivity to glutamate decarboxylase (GAD), involved in the biosynthesis of the neurotransmitter GABA. Thus, in a particular class of retinal neurons, two fast-acting neurotransmitters as well as a putative neuromodulator have been co-localized." @default.
• W2127471192 created "2016-06-24" @default.
• W2127471192 creator A5075225860 @default.
• W2127471192 date "1989-11-01" @default.
• W2127471192 modified "2023-10-18" @default.
• W2127471192 title "Displaced cholinergic, GABAergic amacrine cells in the rabbit retina also contain adenosine" @default.
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• W2127471192 doi "https://doi.org/10.1017/s0952523800005927" @default.
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• W2127471192 hasPublicationYear "1989" @default.
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