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• W2127489318 abstract "Clinical suspicion of SVC syndrome should prompt urgent attention, but in the absence of tracheal obstruction, the symptoms of SVC occlusion are unlikely to prove life threatening. It is therefore possible to consider both the immediate and long-term goals of therapy for the patient with SVC syndrome. Diagnostic procedures of proven value include chest x-rays, chest CT, and nuclear flow studies. A tissue diagnosis should be obtained if possible; noninvasive measures such as sputum cytology have a high success rate. General anesthesia, if required, is usually possible with a low incidence of complications. Treatment of SVC syndrome should be individualized. Small-cell lung cancer and lymphomas respond well to multiagent chemotherapy. Radiotherapy leads to symptomatic improvement in the majority of patients, although long-term survival for those with bronchogenic carcinoma is poor. Patients with indwelling central lines or cardiac pacemakers are at risk of thrombus formation and may require anticoagulation therapy. Surgical reconstruction may be of value in carefully selected patients. Clinical suspicion of SVC syndrome should prompt urgent attention, but in the absence of tracheal obstruction, the symptoms of SVC occlusion are unlikely to prove life threatening. It is therefore possible to consider both the immediate and long-term goals of therapy for the patient with SVC syndrome. Diagnostic procedures of proven value include chest x-rays, chest CT, and nuclear flow studies. A tissue diagnosis should be obtained if possible; noninvasive measures such as sputum cytology have a high success rate. General anesthesia, if required, is usually possible with a low incidence of complications. Treatment of SVC syndrome should be individualized. Small-cell lung cancer and lymphomas respond well to multiagent chemotherapy. Radiotherapy leads to symptomatic improvement in the majority of patients, although long-term survival for those with bronchogenic carcinoma is poor. Patients with indwelling central lines or cardiac pacemakers are at risk of thrombus formation and may require anticoagulation therapy. Surgical reconstruction may be of value in carefully selected patients." @default.
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• W2127489318 date "1993-04-01" @default.
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• W2127489318 title "Approach to the Patient Who Presents With Superior Vena Cava Obstruction" @default.
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• W2127489318 doi "https://doi.org/10.1378/chest.103.4_supplement.394s" @default.
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