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• W2127503471 abstract "We are developing a new class of lanthanide-based self-assembling molecular nanoparticles as potential reporter molecules for imaging, and as multi-functional nanoprobes or nanosensors in diagnostic systems. These lanthanide nano-drums are homogeneous 4d-4f clusters approximately 25 to 30 Å in diameter that can emit from the visible to near-infrared (NIR) wavelengths. Here, we present syntheses, crystal structures, photophysical properties, and comparative cytotoxicity data for six nano-drums containing either Eu, Tb, Lu, Er, Yb or Ho. Imaging capabilities of these nano-drums are demonstrated using epifluorescence, total internal reflection fluorescence (TIRF), and two-photon microscopy. We discuss how these molecular nanoparticles can to be adapted for a range of assays, particularly by taking advantage of functionalization strategies with chemical moieties to enable conjugation to protein or nucleic acids." @default.
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• W2127503471 date "2014-01-01" @default.
• W2127503471 modified "2023-10-14" @default.
• W2127503471 title "Lanthanide nano-drums: a new class of molecular nanoparticles for potential biomedical applications" @default.
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• W2127503471 doi "https://doi.org/10.1039/c4fd00117f" @default.
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