FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2127530256> ?p ?o ?g. }

• W2127530256 endingPage "180" @default.
• W2127530256 startingPage "175" @default.
• W2127530256 abstract "Natural dietary antioxidants are extensively studied for their ability to protect cells from damage to DNA, protein, and lipids induced by antitumor agents or radiation that leads to the generation of free radical in normal cells in vivo and in vitro. Curcumin is a natural antioxidant known to possess therapeutic properties and has been reported to scavenge free radicals and to inhibit clastogenesis in mammalian cells. However, curcumin has been reported to induce a significant increase in the frequency of chromosomal aberrations in Chinese hamster ovary (CHO) cells. To investigate whether the clastogenic activity of curcumin in CHO cells in culture can be ascribed to a pro-oxidant behavior, mediated by free radical generation, experiments were carried out with the combination of curcumin (15 microg/ml) and thiourea (10, 20, or 40 microg/ml), a potent hydroxyl radical scavenger. The results showed that the clastogenic action of curcumin was statistically decreased in a dose-dependent manner in the presence of thiourea. These data have shown that curcumin-induced chromosomal damage in CHO cells can be mediated by hydroxyl radical generation in the present experimental conditions. Teratogenesis Carcinog. Mutagen. 21:175-180, 2001." @default.
• W2127530256 created "2016-06-24" @default.
• W2127530256 creator A5021738955 @default.
• W2127530256 creator A5048668400 @default.
• W2127530256 creator A5057375531 @default.
• W2127530256 date "2001-01-01" @default.
• W2127530256 modified "2023-10-09" @default.
• W2127530256 title "Protective effect of thiourea, a hydroxyl-radical scavenger, on curcumin-induced chromosomal aberrations in an in vitro mammalian cell system" @default.
• W2127530256 cites W1553430971 @default.
• W2127530256 cites W1966087521 @default.
• W2127530256 cites W1968026343 @default.
• W2127530256 cites W1987510808 @default.
• W2127530256 cites W1997747008 @default.
• W2127530256 cites W1997769427 @default.
• W2127530256 cites W2006136207 @default.
• W2127530256 cites W2010839968 @default.
• W2127530256 cites W2031496016 @default.
• W2127530256 cites W2045142972 @default.
• W2127530256 cites W2050361501 @default.
• W2127530256 cites W2051878338 @default.
• W2127530256 cites W2063404271 @default.
• W2127530256 cites W2067070952 @default.
• W2127530256 cites W2090667104 @default.
• W2127530256 cites W2126856423 @default.
• W2127530256 cites W2152626360 @default.
• W2127530256 cites W2167225412 @default.
• W2127530256 cites W2413775972 @default.
• W2127530256 doi "https://doi.org/10.1002/1520-6866(2001)21:2<175::aid-tcm6>3.0.co;2-v" @default.
• W2127530256 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11223894" @default.
• W2127530256 hasPublicationYear "2001" @default.
• W2127530256 type Work @default.
• W2127530256 sameAs 2127530256 @default.
• W2127530256 citedByCount "36" @default.
• W2127530256 countsByYear W21275302562012 @default.
• W2127530256 countsByYear W21275302562013 @default.
• W2127530256 countsByYear W21275302562015 @default.
• W2127530256 countsByYear W21275302562016 @default.
• W2127530256 countsByYear W21275302562017 @default.
• W2127530256 countsByYear W21275302562018 @default.
• W2127530256 countsByYear W21275302562019 @default.
• W2127530256 countsByYear W21275302562020 @default.
• W2127530256 countsByYear W21275302562022 @default.
• W2127530256 countsByYear W21275302562023 @default.
• W2127530256 crossrefType "journal-article" @default.
• W2127530256 hasAuthorship W2127530256A5021738955 @default.
• W2127530256 hasAuthorship W2127530256A5048668400 @default.
• W2127530256 hasAuthorship W2127530256A5057375531 @default.
• W2127530256 hasConcept C139066938 @default.
• W2127530256 hasConcept C141710004 @default.
• W2127530256 hasConcept C143425029 @default.
• W2127530256 hasConcept C170493617 @default.
• W2127530256 hasConcept C175656101 @default.
• W2127530256 hasConcept C178790620 @default.
• W2127530256 hasConcept C185592680 @default.
• W2127530256 hasConcept C202751555 @default.
• W2127530256 hasConcept C207001950 @default.
• W2127530256 hasConcept C2776639595 @default.
• W2127530256 hasConcept C2776778087 @default.
• W2127530256 hasConcept C2778004101 @default.
• W2127530256 hasConcept C2778250585 @default.
• W2127530256 hasConcept C2778959862 @default.
• W2127530256 hasConcept C2780538656 @default.
• W2127530256 hasConcept C2781422964 @default.
• W2127530256 hasConcept C29730261 @default.
• W2127530256 hasConcept C2992339995 @default.
• W2127530256 hasConcept C54355233 @default.
• W2127530256 hasConcept C552990157 @default.
• W2127530256 hasConcept C55493867 @default.
• W2127530256 hasConcept C56783068 @default.
• W2127530256 hasConcept C86803240 @default.
• W2127530256 hasConcept C98274493 @default.
• W2127530256 hasConceptScore W2127530256C139066938 @default.
• W2127530256 hasConceptScore W2127530256C141710004 @default.
• W2127530256 hasConceptScore W2127530256C143425029 @default.
• W2127530256 hasConceptScore W2127530256C170493617 @default.
• W2127530256 hasConceptScore W2127530256C175656101 @default.
• W2127530256 hasConceptScore W2127530256C178790620 @default.
• W2127530256 hasConceptScore W2127530256C185592680 @default.
• W2127530256 hasConceptScore W2127530256C202751555 @default.
• W2127530256 hasConceptScore W2127530256C207001950 @default.
• W2127530256 hasConceptScore W2127530256C2776639595 @default.
• W2127530256 hasConceptScore W2127530256C2776778087 @default.
• W2127530256 hasConceptScore W2127530256C2778004101 @default.
• W2127530256 hasConceptScore W2127530256C2778250585 @default.
• W2127530256 hasConceptScore W2127530256C2778959862 @default.
• W2127530256 hasConceptScore W2127530256C2780538656 @default.
• W2127530256 hasConceptScore W2127530256C2781422964 @default.
• W2127530256 hasConceptScore W2127530256C29730261 @default.
• W2127530256 hasConceptScore W2127530256C2992339995 @default.
• W2127530256 hasConceptScore W2127530256C54355233 @default.
• W2127530256 hasConceptScore W2127530256C552990157 @default.
• W2127530256 hasConceptScore W2127530256C55493867 @default.
• W2127530256 hasConceptScore W2127530256C56783068 @default.
• W2127530256 hasConceptScore W2127530256C86803240 @default.
• W2127530256 hasConceptScore W2127530256C98274493 @default.
• W2127530256 hasIssue "2" @default.
• W2127530256 hasLocation W21275302561 @default.
• W2127530256 hasLocation W21275302562 @default.

• next