FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2127624750> ?p ?o ?g. }

• W2127624750 endingPage "cou058" @default.
• W2127624750 startingPage "cou058" @default.
• W2127624750 abstract "Stress-induced concentrations of glucocorticoid hormones (including corticosterone, CORT) can be suppressed by chronic exposure to a low dose of ingested petroleum. However, endocrine-disrupting chemicals could interfere with CORT signalling beyond the disruption of hormone titres, including effects on receptors in different target tissues. In this study, we examined the effects of 6 weeks of exposure to a petroleum-laced diet (1% oil weight:food weight) on tissue mass and intracellular CORT receptors in liver, fat, muscle and kidney (metabolic tissues), spleen (an immune tissue) and testes (a reproductive tissue). In the laboratory, male house sparrows were fed either a 1% weathered crude oil (n = 12) or a control diet (n = 12); glucocorticoid receptors and mineralocorticoid receptors were quantified using radioligand binding assays. In oil-exposed birds, glucocorticoid receptors were lower in one metabolic tissue (liver), higher in another metabolic tissue (fat) and unchanged in four other tissues (kidney, muscle, spleen and testes) compared with control birds. We saw no differences in mineralocorticoid receptors between groups. We also saw a trend towards reduced mass of the testes in oil-exposed birds compared with controls, but no differences in fat, kidney, liver, muscle or spleen mass between the two groups. This is the first study to examine the effects of petroleum on CORT receptor density in more than one or two target tissues. Given that a chronic low dose of ingested petroleum can affect stress-induced CORT titres as well as receptor density, this demonstrates that oil can act at multiple levels to disrupt an animal's response to environmental stressors. This also highlights the potential usefulness of the stress response as a bioindicator of chronic crude oil exposure." @default.
• W2127624750 created "2016-06-24" @default.
• W2127624750 creator A5038998667 @default.
• W2127624750 creator A5079375127 @default.
• W2127624750 date "2014-12-03" @default.
• W2127624750 modified "2023-10-16" @default.
• W2127624750 title "Chronic exposure to a low dose of ingested petroleum disrupts corticosterone receptor signalling in a tissue-specific manner in the house sparrow (Passer domesticus)" @default.
• W2127624750 cites W12602607 @default.
• W2127624750 cites W1935479846 @default.
• W2127624750 cites W1968907981 @default.
• W2127624750 cites W1969121090 @default.
• W2127624750 cites W1975072002 @default.
• W2127624750 cites W1976871142 @default.
• W2127624750 cites W1980182503 @default.
• W2127624750 cites W1987221420 @default.
• W2127624750 cites W1990137921 @default.
• W2127624750 cites W1992690084 @default.
• W2127624750 cites W2001594506 @default.
• W2127624750 cites W2005638112 @default.
• W2127624750 cites W2013413404 @default.
• W2127624750 cites W2014049736 @default.
• W2127624750 cites W2018534859 @default.
• W2127624750 cites W2026200312 @default.
• W2127624750 cites W2026745417 @default.
• W2127624750 cites W2026745798 @default.
• W2127624750 cites W2029026072 @default.
• W2127624750 cites W2035617742 @default.
• W2127624750 cites W2036191676 @default.
• W2127624750 cites W2038264919 @default.
• W2127624750 cites W2038893397 @default.
• W2127624750 cites W2040549149 @default.
• W2127624750 cites W2050118432 @default.
• W2127624750 cites W2052509497 @default.
• W2127624750 cites W2053131174 @default.
• W2127624750 cites W2055516348 @default.
• W2127624750 cites W2055806024 @default.
• W2127624750 cites W2058496646 @default.
• W2127624750 cites W2059950877 @default.
• W2127624750 cites W2061900620 @default.
• W2127624750 cites W2071747852 @default.
• W2127624750 cites W2071833177 @default.
• W2127624750 cites W2075022249 @default.
• W2127624750 cites W2076153175 @default.
• W2127624750 cites W2079998168 @default.
• W2127624750 cites W2082638240 @default.
• W2127624750 cites W2091322528 @default.
• W2127624750 cites W2091741139 @default.
• W2127624750 cites W2096570309 @default.
• W2127624750 cites W2109190170 @default.
• W2127624750 cites W2113187476 @default.
• W2127624750 cites W2114231575 @default.
• W2127624750 cites W2115989713 @default.
• W2127624750 cites W2118291105 @default.
• W2127624750 cites W2126168000 @default.
• W2127624750 cites W2132539548 @default.
• W2127624750 cites W2137983447 @default.
• W2127624750 cites W2141067845 @default.
• W2127624750 cites W2146684051 @default.
• W2127624750 cites W2148256384 @default.
• W2127624750 cites W2151105455 @default.
• W2127624750 cites W2152760742 @default.
• W2127624750 cites W2167076734 @default.
• W2127624750 cites W2170155178 @default.
• W2127624750 cites W2171238991 @default.
• W2127624750 cites W2180982679 @default.
• W2127624750 cites W269318902 @default.
• W2127624750 cites W2802450554 @default.
• W2127624750 cites W4237348831 @default.
• W2127624750 cites W4242584517 @default.
• W2127624750 cites W4251812107 @default.
• W2127624750 cites W2414267717 @default.
• W2127624750 doi "https://doi.org/10.1093/conphys/cou058" @default.
• W2127624750 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4732471" @default.
• W2127624750 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27293679" @default.
• W2127624750 hasPublicationYear "2014" @default.
• W2127624750 type Work @default.
• W2127624750 sameAs 2127624750 @default.
• W2127624750 citedByCount "10" @default.
• W2127624750 countsByYear W21276247502015 @default.
• W2127624750 countsByYear W21276247502017 @default.
• W2127624750 countsByYear W21276247502018 @default.
• W2127624750 countsByYear W21276247502019 @default.
• W2127624750 countsByYear W21276247502021 @default.
• W2127624750 countsByYear W21276247502022 @default.
• W2127624750 crossrefType "journal-article" @default.
• W2127624750 hasAuthorship W2127624750A5038998667 @default.
• W2127624750 hasAuthorship W2127624750A5079375127 @default.
• W2127624750 hasBestOaLocation W21276247501 @default.
• W2127624750 hasConcept C126322002 @default.
• W2127624750 hasConcept C134018914 @default.
• W2127624750 hasConcept C170493617 @default.
• W2127624750 hasConcept C171089720 @default.
• W2127624750 hasConcept C189135053 @default.
• W2127624750 hasConcept C203014093 @default.
• W2127624750 hasConcept C2776069600 @default.
• W2127624750 hasConcept C2778525890 @default.
• W2127624750 hasConcept C2780091579 @default.
• W2127624750 hasConcept C2780352252 @default.

• next