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- W2127627590 abstract "Summary The clustered regularly interspaced short palindromic repeat – CRISPR‐associated genes ( CRISPR‐C as) system is used by bacteria and archaea against invading conjugative plasmids or bacteriophages. Central to this immunity system are genomic CRISPR loci that contain fragments of invading DNA . These are maintained as spacers in the CRISPR loci between direct repeats and the spacer composition in any bacterium reflects its evolutionary history. We analysed the CRISPR locus sequences of 335 Y ersinia pseudotuberculosis complex strains. Altogether 1902 different spacer sequences were identified and these were used to generate a database for the spacer sequences. Only ∼10% of the spacer sequences found matching sequences. In addition, surprisingly few spacers were shared by Y ersinia pestis and Y . pseudotuberculosis strains. Interestingly, 32 different protospacers were present in the conjugative plasmid pYptb 32953. The corresponding spacers were identified from 35 different Y . pseudotuberculosis strains indicating that these strains had encountered pYptb 32953 earlier. In conjugation experiments, pYptb 32953‐specific spacers generally prevented conjugation with spacer‐positive and spacer‐free strains. However, some strains with one to four spacers were invaded by pYptb 32953 and some spacer‐free strains were fully resistant. Also some spacer‐positive strains were intermediate resistant to conjugation. This suggests that one or more other defence systems are determining conjugation efficiency independent of the CRISPR‐Cas system." @default.
- W2127627590 created "2016-06-24" @default.
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- W2127627590 date "2015-03-27" @default.
- W2127627590 modified "2023-10-02" @default.
- W2127627590 title "Generation of a CRISPR database for<i>Y</i><i>ersinia pseudotuberculosis</i>complex and role of CRISPR-based immunity in conjugation" @default.
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- W2127627590 cites W1965632328 @default.
- W2127627590 cites W1969599563 @default.
- W2127627590 cites W1970515032 @default.
- W2127627590 cites W1972428380 @default.
- W2127627590 cites W1974127479 @default.
- W2127627590 cites W1978094899 @default.
- W2127627590 cites W1984164827 @default.
- W2127627590 cites W1986171241 @default.
- W2127627590 cites W2005870584 @default.
- W2127627590 cites W2008665793 @default.
- W2127627590 cites W2008897847 @default.
- W2127627590 cites W2008911461 @default.
- W2127627590 cites W2015316514 @default.
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- W2127627590 cites W2170649615 @default.
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- W2127627590 doi "https://doi.org/10.1111/1462-2920.12816" @default.
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