FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2127693634> ?p ?o ?g. }

• W2127693634 endingPage "2116" @default.
• W2127693634 startingPage "2108" @default.
• W2127693634 abstract "The RNA polymerase (pol) III-transcribed (e.g. tRNA and 5S rRNA) genes of traditionally studied organisms rely on gene-internal promoters that precisely position the initiation factor, TFIIIB, on the upstream promoter-less DNA. This is accomplished by the ability of the TFIIIB subunit, TFIIB-related factor (Brf1), to make stable protein-protein interactions with TATA-binding protein (TBP) and place it on the promoter-less upstream DNA. Unlike traditional model organisms, Schizosaccharomyces pombe tRNA and 5S rRNA genes contain upstream TATA promoters that are required to program functional pol III initiation complexes. In this study we demonstrate that S.pombe (Sp)Brf does not form stable interactions with TBP in the absence of DNA using approaches that do reveal stable association of TBP and S.cerevisiae (Sc)Brf1. Gel mobility analyses demonstrate that a TBP-TATA DNA complex can recruit SpBrf to a Pol III promoter. Consistent with this, overproduction of SpBrf in S.pombe increases the expression of a TATA-dependent, but not a TATA-less, suppressor tRNA gene. Since previous whole genome analysis also revealed TATA elements upstream of tRNA genes in Arabidopsis, this pathway may be more widespread than appreciated previously." @default.
• W2127693634 created "2016-06-24" @default.
• W2127693634 creator A5020115662 @default.
• W2127693634 date "2003-04-15" @default.
• W2127693634 modified "2023-09-26" @default.
• W2127693634 title "The fission yeast TFIIB-related factor limits RNA polymerase III to a TATA-dependent pathway of TBP recruitment" @default.
• W2127693634 cites W1513355023 @default.
• W2127693634 cites W1537782690 @default.
• W2127693634 cites W1543188612 @default.
• W2127693634 cites W1548777710 @default.
• W2127693634 cites W1552410847 @default.
• W2127693634 cites W1855181403 @default.
• W2127693634 cites W1876905084 @default.
• W2127693634 cites W1968764028 @default.
• W2127693634 cites W1975235708 @default.
• W2127693634 cites W1978814343 @default.
• W2127693634 cites W1985235553 @default.
• W2127693634 cites W1985254307 @default.
• W2127693634 cites W1994562071 @default.
• W2127693634 cites W2003188984 @default.
• W2127693634 cites W2004712619 @default.
• W2127693634 cites W2006630070 @default.
• W2127693634 cites W2011369010 @default.
• W2127693634 cites W2013296976 @default.
• W2127693634 cites W2020267592 @default.
• W2127693634 cites W2020300023 @default.
• W2127693634 cites W2022101620 @default.
• W2127693634 cites W2035816111 @default.
• W2127693634 cites W2040690000 @default.
• W2127693634 cites W2042425655 @default.
• W2127693634 cites W2043683039 @default.
• W2127693634 cites W2053652297 @default.
• W2127693634 cites W2054591386 @default.
• W2127693634 cites W2059198116 @default.
• W2127693634 cites W2061970520 @default.
• W2127693634 cites W2063291840 @default.
• W2127693634 cites W2063826622 @default.
• W2127693634 cites W2070889260 @default.
• W2127693634 cites W2073515063 @default.
• W2127693634 cites W2073932060 @default.
• W2127693634 cites W2078864996 @default.
• W2127693634 cites W2080462057 @default.
• W2127693634 cites W2081313130 @default.
• W2127693634 cites W2082395806 @default.
• W2127693634 cites W2086315977 @default.
• W2127693634 cites W2090706358 @default.
• W2127693634 cites W2096567462 @default.
• W2127693634 cites W2101510684 @default.
• W2127693634 cites W2104375994 @default.
• W2127693634 cites W2108508097 @default.
• W2127693634 cites W2110753148 @default.
• W2127693634 cites W2115428749 @default.
• W2127693634 cites W2118370642 @default.
• W2127693634 cites W2121085084 @default.
• W2127693634 cites W2133527699 @default.
• W2127693634 cites W2137186081 @default.
• W2127693634 cites W2139919019 @default.
• W2127693634 cites W2140235682 @default.
• W2127693634 cites W2144994561 @default.
• W2127693634 cites W2157126743 @default.
• W2127693634 cites W2157379699 @default.
• W2127693634 cites W2162204218 @default.
• W2127693634 doi "https://doi.org/10.1093/nar/gkg301" @default.
• W2127693634 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/153730" @default.
• W2127693634 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12682361" @default.
• W2127693634 hasPublicationYear "2003" @default.
• W2127693634 type Work @default.
• W2127693634 sameAs 2127693634 @default.
• W2127693634 citedByCount "9" @default.
• W2127693634 countsByYear W21276936342012 @default.
• W2127693634 countsByYear W21276936342013 @default.
• W2127693634 countsByYear W21276936342015 @default.
• W2127693634 crossrefType "journal-article" @default.
• W2127693634 hasAuthorship W2127693634A5020115662 @default.
• W2127693634 hasBestOaLocation W21276936341 @default.
• W2127693634 hasConcept C101762097 @default.
• W2127693634 hasConcept C104317684 @default.
• W2127693634 hasConcept C105208137 @default.
• W2127693634 hasConcept C150194340 @default.
• W2127693634 hasConcept C153911025 @default.
• W2127693634 hasConcept C153957851 @default.
• W2127693634 hasConcept C172768829 @default.
• W2127693634 hasConcept C2776449523 @default.
• W2127693634 hasConcept C2777576037 @default.
• W2127693634 hasConcept C2779429346 @default.
• W2127693634 hasConcept C2780055153 @default.
• W2127693634 hasConcept C2909959438 @default.
• W2127693634 hasConcept C44498088 @default.
• W2127693634 hasConcept C54355233 @default.
• W2127693634 hasConcept C64350747 @default.
• W2127693634 hasConcept C65888428 @default.
• W2127693634 hasConcept C67705224 @default.
• W2127693634 hasConcept C70916841 @default.
• W2127693634 hasConcept C86803240 @default.
• W2127693634 hasConceptScore W2127693634C101762097 @default.
• W2127693634 hasConceptScore W2127693634C104317684 @default.
• W2127693634 hasConceptScore W2127693634C105208137 @default.
• W2127693634 hasConceptScore W2127693634C150194340 @default.

• next