FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2127756987> ?p ?o ?g. }

• W2127756987 endingPage "478" @default.
• W2127756987 startingPage "473" @default.
• W2127756987 abstract "Since the dorsal root ganglia represent the first structure of pain modulation, they are the target of the newest therapies of neuropathic pain. Between these, pulsed radiofrequency (PRF) has been described among the promising non-invasive methods. Although the results encourage the clinical use of this procedure, their mechanism of action is still unclear. Aim of our study was to analyze acute effects of PRF on the rat lumbar ganglion and on nervous fibres running inside it. Clinical works describe PRF treatment as a techinque without any visible neurological deficit. The few disposable histological works are contractictory: some describe no signs of cellular damage and some demonstrate visible intracellular modifications. A total of 20 male Wistar rats were deeply anesthesized. Ten were positioned in a stereotactic system, and exposed to PRF at 2 Hz for 30 s after exposition of paravertebral muscles and positioning of a stimulation needle on left L4 ganglion. The other ten were used as controls. After 1 h, the left dorsal root ganglions L3, L4, L5 of the 20 animals were explanted, fixed in 2.5% Karnowsky solution and prepared for light and transmission electron microscopy. At light microscopy no differences between treated and control animals were observed; at transmission electron microscopy, instead, it was possible to observe that T gangliar cells contained an abnormal abundant smooth reticulum with enlarged cisternae and numerous vacuoles; myelinated axons presented pathological features and their myelin coverage was not adherent. Instead, unmyelinated axons appeared normal in shape and dimension and the Schwann cells surrounding it had intact plasmamembrane. Our results, obtained at acute stage, reveal that the PRF procedure should destroy the myelin envelope of nervous fibres. Further future studies, at chronic stage, should give other information on the prognosis of the myelinic damage." @default.
• W2127756987 created "2016-06-24" @default.
• W2127756987 creator A5007772278 @default.
• W2127756987 creator A5008333646 @default.
• W2127756987 creator A5008902076 @default.
• W2127756987 creator A5011114343 @default.
• W2127756987 creator A5039446481 @default.
• W2127756987 creator A5043316357 @default.
• W2127756987 creator A5069907344 @default.
• W2127756987 creator A5071007892 @default.
• W2127756987 creator A5077846233 @default.
• W2127756987 date "2009-01-27" @default.
• W2127756987 modified "2023-10-18" @default.
• W2127756987 title "Pulsed radiofrequency effects on the lumbar ganglion of the rat dorsal root: a morphological light and transmission electron microscopy study at acute stage" @default.
• W2127756987 cites W1883448081 @default.
• W2127756987 cites W1971887945 @default.
• W2127756987 cites W1975161966 @default.
• W2127756987 cites W1993133058 @default.
• W2127756987 cites W1996146557 @default.
• W2127756987 cites W2009685905 @default.
• W2127756987 cites W2031415485 @default.
• W2127756987 cites W2037933074 @default.
• W2127756987 cites W2050194795 @default.
• W2127756987 cites W2058640828 @default.
• W2127756987 cites W2063655624 @default.
• W2127756987 cites W2093054937 @default.
• W2127756987 cites W2123546299 @default.
• W2127756987 cites W2156332671 @default.
• W2127756987 cites W2170995281 @default.
• W2127756987 doi "https://doi.org/10.1007/s00586-008-0870-z" @default.
• W2127756987 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2899462" @default.
• W2127756987 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19172311" @default.
• W2127756987 hasPublicationYear "2009" @default.
• W2127756987 type Work @default.
• W2127756987 sameAs 2127756987 @default.
• W2127756987 citedByCount "48" @default.
• W2127756987 countsByYear W21277569872012 @default.
• W2127756987 countsByYear W21277569872013 @default.
• W2127756987 countsByYear W21277569872014 @default.
• W2127756987 countsByYear W21277569872015 @default.
• W2127756987 countsByYear W21277569872016 @default.
• W2127756987 countsByYear W21277569872017 @default.
• W2127756987 countsByYear W21277569872018 @default.
• W2127756987 countsByYear W21277569872019 @default.
• W2127756987 countsByYear W21277569872020 @default.
• W2127756987 countsByYear W21277569872021 @default.
• W2127756987 countsByYear W21277569872022 @default.
• W2127756987 countsByYear W21277569872023 @default.
• W2127756987 crossrefType "journal-article" @default.
• W2127756987 hasAuthorship W2127756987A5007772278 @default.
• W2127756987 hasAuthorship W2127756987A5008333646 @default.
• W2127756987 hasAuthorship W2127756987A5008902076 @default.
• W2127756987 hasAuthorship W2127756987A5011114343 @default.
• W2127756987 hasAuthorship W2127756987A5039446481 @default.
• W2127756987 hasAuthorship W2127756987A5043316357 @default.
• W2127756987 hasAuthorship W2127756987A5069907344 @default.
• W2127756987 hasAuthorship W2127756987A5071007892 @default.
• W2127756987 hasAuthorship W2127756987A5077846233 @default.
• W2127756987 hasBestOaLocation W21277569872 @default.
• W2127756987 hasConcept C105702510 @default.
• W2127756987 hasConcept C120665830 @default.
• W2127756987 hasConcept C121332964 @default.
• W2127756987 hasConcept C140530291 @default.
• W2127756987 hasConcept C142724271 @default.
• W2127756987 hasConcept C2776281502 @default.
• W2127756987 hasConcept C2780934536 @default.
• W2127756987 hasConcept C2781334511 @default.
• W2127756987 hasConcept C2993247534 @default.
• W2127756987 hasConcept C42219234 @default.
• W2127756987 hasConcept C44575665 @default.
• W2127756987 hasConcept C71924100 @default.
• W2127756987 hasConcept C93877712 @default.
• W2127756987 hasConceptScore W2127756987C105702510 @default.
• W2127756987 hasConceptScore W2127756987C120665830 @default.
• W2127756987 hasConceptScore W2127756987C121332964 @default.
• W2127756987 hasConceptScore W2127756987C140530291 @default.
• W2127756987 hasConceptScore W2127756987C142724271 @default.
• W2127756987 hasConceptScore W2127756987C2776281502 @default.
• W2127756987 hasConceptScore W2127756987C2780934536 @default.
• W2127756987 hasConceptScore W2127756987C2781334511 @default.
• W2127756987 hasConceptScore W2127756987C2993247534 @default.
• W2127756987 hasConceptScore W2127756987C42219234 @default.
• W2127756987 hasConceptScore W2127756987C44575665 @default.
• W2127756987 hasConceptScore W2127756987C71924100 @default.
• W2127756987 hasConceptScore W2127756987C93877712 @default.
• W2127756987 hasIssue "4" @default.
• W2127756987 hasLocation W21277569871 @default.
• W2127756987 hasLocation W21277569872 @default.
• W2127756987 hasLocation W21277569873 @default.
• W2127756987 hasLocation W21277569874 @default.
• W2127756987 hasOpenAccess W2127756987 @default.
• W2127756987 hasPrimaryLocation W21277569871 @default.
• W2127756987 hasRelatedWork W1995966188 @default.
• W2127756987 hasRelatedWork W2025845444 @default.
• W2127756987 hasRelatedWork W2027973740 @default.
• W2127756987 hasRelatedWork W2047567457 @default.
• W2127756987 hasRelatedWork W2082089678 @default.
• W2127756987 hasRelatedWork W2083703979 @default.

• next