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- W2127805193 abstract "To validate the pathologoical flow condition as the etiology of site-specific athero sclerosis, computer simulation and analysis are presented. Two extreme pulsatile flows, as have been measured in human femoral arteries, are used to numerically simulate in-vivo blood flow. The pulse with a steep temporal velocity gradient is assigned as “steep” pulse whereas the one with a lesser slope is called “less-steep” pulse. The effect of the extreme two pulses on the injury of endothelial cells in a 90° femoral artery of human is investigated by calculating flow parameters including instantaneous wall shear stresses. At the proximal and the distal branch apex, the oscillating wall shear stresses calculated from the ‘steep’ pulse cycle are found to be substantially greater than those from the ‘less-steep’ one. In contrast, for a straight artery, insignificant changes in flow parameters are observed for the extreme two pulses. It is evident from the calculated local wall shear stress that pathological changes can o..." @default.
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- W2127805193 date "1998-01-01" @default.
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- W2127805193 title "A Study of Local Hydrodynamics in a 90°Branched Vessel with Extreme Pulsatile Flows" @default.
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- W2127805193 doi "https://doi.org/10.1080/10618569808940838" @default.
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