Matches in SemOpenAlex for { <https://semopenalex.org/work/W2127820682> ?p ?o ?g. }
- W2127820682 endingPage "2168" @default.
- W2127820682 startingPage "2160" @default.
- W2127820682 abstract "Learning how to obtain rewards requires learning about their contexts and likely causes. How do long-term memory mechanisms balance the need to represent potential determinants of reward outcomes with the computational burden of an over-inclusive memory? One solution would be to enhance memory for salient events that occur during reward anticipation, because all such events are potential determinants of reward. We tested whether reward motivation enhances encoding of salient events like expectancy violations. During functional magnetic resonance imaging, participants performed a reaction-time task in which goal-irrelevant expectancy violations were encountered during states of high- or low-reward motivation. Motivation amplified hippocampal activation to and declarative memory for expectancy violations. Connectivity of the ventral tegmental area (VTA) with medial prefrontal, ventrolateral prefrontal, and visual cortices preceded and predicted this increase in hippocampal sensitivity. These findings elucidate a novel mechanism whereby reward motivation can enhance hippocampus-dependent memory: anticipatory VTA-cortical-hippocampal interactions. Further, the findings integrate literatures on dopaminergic neuromodulation of prefrontal function and hippocampus-dependent memory. We conclude that during reward motivation, VTA modulation induces distributed neural changes that amplify hippocampal signals and records of expectancy violations to improve predictions-a potentially unique contribution of the hippocampus to reward learning." @default.
- W2127820682 created "2016-06-24" @default.
- W2127820682 creator A5023153459 @default.
- W2127820682 creator A5072697564 @default.
- W2127820682 date "2013-03-25" @default.
- W2127820682 modified "2023-10-12" @default.
- W2127820682 title "Enriched Encoding: Reward Motivation Organizes Cortical Networks for Hippocampal Detection of Unexpected Events" @default.
- W2127820682 cites W1604195904 @default.
- W2127820682 cites W1659384861 @default.
- W2127820682 cites W1966647730 @default.
- W2127820682 cites W1967922673 @default.
- W2127820682 cites W1973371295 @default.
- W2127820682 cites W1975705681 @default.
- W2127820682 cites W1978660262 @default.
- W2127820682 cites W1979247311 @default.
- W2127820682 cites W1980737345 @default.
- W2127820682 cites W1985942784 @default.
- W2127820682 cites W1988220777 @default.
- W2127820682 cites W1994728257 @default.
- W2127820682 cites W1998127479 @default.
- W2127820682 cites W1999300426 @default.
- W2127820682 cites W2008709921 @default.
- W2127820682 cites W2014617728 @default.
- W2127820682 cites W2019370496 @default.
- W2127820682 cites W2037457092 @default.
- W2127820682 cites W2040382032 @default.
- W2127820682 cites W2051971539 @default.
- W2127820682 cites W2056752073 @default.
- W2127820682 cites W2060322330 @default.
- W2127820682 cites W2061170062 @default.
- W2127820682 cites W2066824070 @default.
- W2127820682 cites W2071881327 @default.
- W2127820682 cites W2077119523 @default.
- W2127820682 cites W2081531505 @default.
- W2127820682 cites W2082907353 @default.
- W2127820682 cites W2084007108 @default.
- W2127820682 cites W2084391069 @default.
- W2127820682 cites W2089147021 @default.
- W2127820682 cites W2091282625 @default.
- W2127820682 cites W2095827013 @default.
- W2127820682 cites W2097889405 @default.
- W2127820682 cites W2098273086 @default.
- W2127820682 cites W2100564223 @default.
- W2127820682 cites W2104069712 @default.
- W2127820682 cites W2104533848 @default.
- W2127820682 cites W2107669731 @default.
- W2127820682 cites W2109738307 @default.
- W2127820682 cites W2111464173 @default.
- W2127820682 cites W2111873046 @default.
- W2127820682 cites W2114207481 @default.
- W2127820682 cites W2120249508 @default.
- W2127820682 cites W2121007598 @default.
- W2127820682 cites W2124412681 @default.
- W2127820682 cites W2127006344 @default.
- W2127820682 cites W2127190848 @default.
- W2127820682 cites W2130099840 @default.
- W2127820682 cites W2130674184 @default.
- W2127820682 cites W2136347166 @default.
- W2127820682 cites W2136706948 @default.
- W2127820682 cites W2137448503 @default.
- W2127820682 cites W2142281591 @default.
- W2127820682 cites W2143292369 @default.
- W2127820682 cites W2150185446 @default.
- W2127820682 cites W2150857753 @default.
- W2127820682 cites W2153599086 @default.
- W2127820682 cites W2156466070 @default.
- W2127820682 cites W2159010963 @default.
- W2127820682 cites W2165706889 @default.
- W2127820682 cites W2165728411 @default.
- W2127820682 cites W2169963116 @default.
- W2127820682 cites W2171856250 @default.
- W2127820682 cites W4235770099 @default.
- W2127820682 doi "https://doi.org/10.1093/cercor/bht063" @default.
- W2127820682 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4089383" @default.
- W2127820682 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23529005" @default.
- W2127820682 hasPublicationYear "2013" @default.
- W2127820682 type Work @default.
- W2127820682 sameAs 2127820682 @default.
- W2127820682 citedByCount "117" @default.
- W2127820682 countsByYear W21278206822014 @default.
- W2127820682 countsByYear W21278206822015 @default.
- W2127820682 countsByYear W21278206822016 @default.
- W2127820682 countsByYear W21278206822017 @default.
- W2127820682 countsByYear W21278206822018 @default.
- W2127820682 countsByYear W21278206822019 @default.
- W2127820682 countsByYear W21278206822020 @default.
- W2127820682 countsByYear W21278206822021 @default.
- W2127820682 countsByYear W21278206822022 @default.
- W2127820682 countsByYear W21278206822023 @default.
- W2127820682 crossrefType "journal-article" @default.
- W2127820682 hasAuthorship W2127820682A5023153459 @default.
- W2127820682 hasAuthorship W2127820682A5072697564 @default.
- W2127820682 hasBestOaLocation W21278206821 @default.
- W2127820682 hasConcept C125411270 @default.
- W2127820682 hasConcept C137183658 @default.
- W2127820682 hasConcept C148762608 @default.
- W2127820682 hasConcept C154945302 @default.
- W2127820682 hasConcept C15744967 @default.