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- W2127846730 abstract "The ability of tumor cells to interact with platelets constitutes an indispensable determinant in the success of metastatic spread. This study was undertaken to investigate the sequence of molecular events mediating human colon (LS174T) carcinoma cell adhesion to surface adherent platelets under flow. A two-step process of tumor cell recruitment has been elucidated, involving LS174T tethering mediated primarily by platelet P-selectin, and subsequent arrest via platelet /spl alpha//sub IIb//spl beta//sub 3/. This cascade of events depicts an efficacious process for colon carcinoma arrest at sites of vascular injury." @default.
- W2127846730 created "2016-06-24" @default.
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- W2127846730 date "2003-01-20" @default.
- W2127846730 modified "2023-09-25" @default.
- W2127846730 title "Molecular mechanisms of platelet-tumor cell adhesion under flow" @default.
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- W2127846730 doi "https://doi.org/10.1109/iembs.1999.802096" @default.
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