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• W2127857908 abstract "The recommended treatment for Q fever endocarditis is a combination of doxycycline and hydroxychloroquine. We found a correlation between serum doxycycline concentrations and decreases in levels of phase 1 Coxiella burnetii antibodies, in 24 patients with Q fever endocarditis. Patients who had a >2-fold decrease in levels of phase 1 antibodies had serum doxycycline concentrations higher than those of the other patients (mean+/-SD, 5.29+/-1.75 vs. 3.14+/-1.40 microg/mL; P=.003). We recommend adjusting the posology of doxycycline to achieve a serum concentration of at least 5 microg/mL." @default.
• W2127857908 created "2016-06-24" @default.
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• W2127857908 date "2003-11-01" @default.
• W2127857908 modified "2023-10-12" @default.
• W2127857908 title "Correlation between Serum Doxycycline Concentrations and Serologic Evolution in Patients with<i>Coxiella burnetii</i>Endocarditis" @default.
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• W2127857908 doi "https://doi.org/10.1086/379082" @default.
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