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• W2128014934 endingPage "2182" @default.
• W2128014934 startingPage "2173" @default.
• W2128014934 abstract "The 24 kbp KpnI restriction fragment A from the unique long genome region of infectious laryngotracheitis virus (ILTV, gallid herpesvirus-1) has been sequenced. The analysed region contains 14 open reading frames sharing homology with conserved alphaherpesvirus genes. Arrangement of the UL6 to UL20 homologues of ILTV is almost identical to that found in the herpes simplex virus type 1 genome. As in other herpesviruses the UL15 gene consists of two exons and is expressed from a spliced mRNA. However, the UL16 gene, which is usually localized within the intron sequence of UL15, is not conserved at this position of the ILTV genome. Another unique feature is the absence of any putative N-glycosylation motifs within the deduced ILTV UL10 gene product, which is the homologue of the conserved herpesvirus glycoprotein M. After preparation of a monospecific antiserum, two distinct UL10 proteins with apparent molecular masses of 36 and 31 kDa were identified in ILTV-infected cells as well as in purified virions. None of these UL10 gene products is modified by N- or O-linked glycosylation. Isolation of a green fluorescent protein-expressing UL10 deletion mutant of ILTV revealed that this gene is not required for virus replication in cell culture." @default.
• W2128014934 created "2016-06-24" @default.
• W2128014934 creator A5046671398 @default.
• W2128014934 creator A5049949632 @default.
• W2128014934 date "1999-08-01" @default.
• W2128014934 modified "2023-09-24" @default.
• W2128014934 title "DNA sequence of the UL6 to UL20 genes of infectious laryngotracheitis virus and characterization of the UL10 gene product as a nonglycosylated and nonessential virion protein" @default.
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• W2128014934 doi "https://doi.org/10.1099/0022-1317-80-8-2173" @default.
• W2128014934 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10466817" @default.
• W2128014934 hasPublicationYear "1999" @default.
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