FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2128015772> ?p ?o ?g. }

• W2128015772 endingPage "21136" @default.
• W2128015772 startingPage "21120" @default.
• W2128015772 abstract "// Yu-Ching Wen 1,2 , Wei-Jiunn Lee 2 , Peng Tan 1 , Shun-Fa Yang 3,4 , Michael Hsiao 5 , Liang-Ming Lee 2 and Ming-Hsien Chien 1,6 1 Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan 2 Department of Urology, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan 3 Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan 4 Department of Medical Research, Chung Shan Medical University Hospital, Taichung, Taiwan 5 The Genomics Research Center, Academia Sinica; Taipei, Taiwan 6 Department of Education and Research, Wan Fang Hospital, Taipei Medical University, Taipei, Taiwan Correspondence to: Ming-Hsien Chien, email: // Liang-Ming Lee, email: // Keywords : prostate cancer, miR-23a-3p, snail, EMT, osthole Received : March 12, 2015 Accepted : May 13, 2015 Published : May 22, 2015 Abstract Here we showed that Osthole, 7-methoxy-8-(3-methyl-2-butenyl) coumarin, a bioactive coumarin derivative extracted from medicinal plants, inhibited migration, invasion, epithelial to mesenchymal transition (EMT) in androgen-independent prostate cancer (AIPC) cells in vitro and metastasis of AIPC in vivo . In patients, high Snail levels were correlated with a higher histological Gleason sum and poor survival rates. Osthole inhibited the TGF-β/Akt/MAPK pathways, reduced Snail-DNA-binding activity and induced E-cadherin. We found that osthole decreased miR-23a-3p. Ectopic miR-23a-3p suppressed E-cadherin 3’ untranslated region reporter activity and E-cadherin expression, and relieved the motility suppression caused by osthole treatment." @default.
• W2128015772 created "2016-06-24" @default.
• W2128015772 creator A5031594831 @default.
• W2128015772 creator A5040836988 @default.
• W2128015772 creator A5044070285 @default.
• W2128015772 creator A5047705180 @default.
• W2128015772 creator A5056234160 @default.
• W2128015772 creator A5060183326 @default.
• W2128015772 creator A5062664426 @default.
• W2128015772 date "2015-05-22" @default.
• W2128015772 modified "2023-10-12" @default.
• W2128015772 title "By inhibiting snail signaling and miR-23a-3p, osthole suppresses the EMT-mediated metastatic ability in prostate cancer" @default.
• W2128015772 cites W1560761903 @default.
• W2128015772 cites W1740737174 @default.
• W2128015772 cites W1760215417 @default.
• W2128015772 cites W1963995106 @default.
• W2128015772 cites W1965747060 @default.
• W2128015772 cites W1975360068 @default.
• W2128015772 cites W1976324983 @default.
• W2128015772 cites W1979802274 @default.
• W2128015772 cites W1982895658 @default.
• W2128015772 cites W1983794260 @default.
• W2128015772 cites W1983991097 @default.
• W2128015772 cites W1986911605 @default.
• W2128015772 cites W1988106226 @default.
• W2128015772 cites W1990254412 @default.
• W2128015772 cites W1996118868 @default.
• W2128015772 cites W1998912122 @default.
• W2128015772 cites W2001012450 @default.
• W2128015772 cites W2001740655 @default.
• W2128015772 cites W2004339436 @default.
• W2128015772 cites W2009215637 @default.
• W2128015772 cites W2010831408 @default.
• W2128015772 cites W2014946489 @default.
• W2128015772 cites W2016353415 @default.
• W2128015772 cites W2016414500 @default.
• W2128015772 cites W2035653659 @default.
• W2128015772 cites W2039213901 @default.
• W2128015772 cites W2043709265 @default.
• W2128015772 cites W2044967196 @default.
• W2128015772 cites W2046529770 @default.
• W2128015772 cites W2048025180 @default.
• W2128015772 cites W2052720577 @default.
• W2128015772 cites W2056302937 @default.
• W2128015772 cites W2058858453 @default.
• W2128015772 cites W2083312895 @default.
• W2128015772 cites W2087367170 @default.
• W2128015772 cites W2098208011 @default.
• W2128015772 cites W2100158789 @default.
• W2128015772 cites W2100914244 @default.
• W2128015772 cites W2101547995 @default.
• W2128015772 cites W2107630967 @default.
• W2128015772 cites W2118936797 @default.
• W2128015772 cites W2121765586 @default.
• W2128015772 cites W2122557087 @default.
• W2128015772 cites W2124756133 @default.
• W2128015772 cites W2128260729 @default.
• W2128015772 cites W2129580176 @default.
• W2128015772 cites W2135810600 @default.
• W2128015772 cites W2144680000 @default.
• W2128015772 cites W2146445411 @default.
• W2128015772 cites W2153223436 @default.
• W2128015772 cites W2157515211 @default.
• W2128015772 cites W2164079778 @default.
• W2128015772 cites W2170419735 @default.
• W2128015772 cites W2252647763 @default.
• W2128015772 cites W2322585329 @default.
• W2128015772 doi "https://doi.org/10.18632/oncotarget.4229" @default.
• W2128015772 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4673254" @default.
• W2128015772 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26110567" @default.
• W2128015772 hasPublicationYear "2015" @default.
• W2128015772 type Work @default.
• W2128015772 sameAs 2128015772 @default.
• W2128015772 citedByCount "60" @default.
• W2128015772 countsByYear W21280157722015 @default.
• W2128015772 countsByYear W21280157722016 @default.
• W2128015772 countsByYear W21280157722017 @default.
• W2128015772 countsByYear W21280157722018 @default.
• W2128015772 countsByYear W21280157722019 @default.
• W2128015772 countsByYear W21280157722020 @default.
• W2128015772 countsByYear W21280157722021 @default.
• W2128015772 countsByYear W21280157722022 @default.
• W2128015772 countsByYear W21280157722023 @default.
• W2128015772 crossrefType "journal-article" @default.
• W2128015772 hasAuthorship W2128015772A5031594831 @default.
• W2128015772 hasAuthorship W2128015772A5040836988 @default.
• W2128015772 hasAuthorship W2128015772A5044070285 @default.
• W2128015772 hasAuthorship W2128015772A5047705180 @default.
• W2128015772 hasAuthorship W2128015772A5056234160 @default.
• W2128015772 hasAuthorship W2128015772A5060183326 @default.
• W2128015772 hasAuthorship W2128015772A5062664426 @default.
• W2128015772 hasBestOaLocation W21280157721 @default.
• W2128015772 hasConcept C104317684 @default.
• W2128015772 hasConcept C121608353 @default.
• W2128015772 hasConcept C126322002 @default.
• W2128015772 hasConcept C143998085 @default.
• W2128015772 hasConcept C145059251 @default.
• W2128015772 hasConcept C18903297 @default.

• next