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- W2128039201 abstract "We show in this work the development of modified building blocks for the synthesis of nuclease resistant hammerhead ribozymes. These modified monomers retain the 2’-OH which is essential for the activity of these molecules. Our final goal is to generate a catalytic antisense approach with potential application in gene therapy." @default.
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- W2128039201 date "2000-05-15" @default.
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- W2128039201 title "Synthesis of 2’-Modified Nucleotides" @default.
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- W2128039201 doi "https://doi.org/10.3390/50500727" @default.
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