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- W2128049891 abstract "This paper describes the flightless phenotype of the vestigial-Depilate deficiency of Drosophila melanogaster. Recombination experiments and studies of revertants show that the dominant flightless and depilate phenotypes are inseparable from the deficiency and due to a single cause. Dosage studies on this region reveal that these phenotypes are due to antimorphic effects, probably on the Suppressor-2 of zeste or Posteriorsexcomb genes which lie close to the distal breakpoint of the deficiency. The deficiency does not uncover a gene haplo-insufficient for flight. A detailed phenotypic examination failed to reveal any effects of this mutation on the indirect flight muscles. Dr(2R)vgD/+ heterozygotes are unable to initiate flight or raise their wings, even during death by over etherisation. There is a close correlation between the dominant antimorphic flightlessness and patterned thoracic bristle loss which is revealed in interactions with Df(2R)vg62 and the Su(z)2alleles. This is discussed in the light of the bnstle loss mutants of the Achaete-scute complex. It is proposed that the vestigial-Depilate deficiency affects the development of thoracic nerves." @default.
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- W2128049891 date "1989-01-01" @default.
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- W2128049891 title "Dominant flightless phenotype of thevestigial-Depilate deficiency ofDrosophila melanogaster" @default.
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- W2128049891 doi "https://doi.org/10.1002/dvg.1020100205" @default.
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