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Matches in SemOpenAlex for { <https://semopenalex.org/work/W2128232386> ?p ?o ?g. }

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• W2128232386 abstract "The synthesis and the phosphodiesterase-4 (PDE4) inhibitory activity of 2-pyridinemethanol derivatives is described. The evaluation of the structure-activity relationship (SAR) in this series of novel PDE4 inhibitors led to the identification of compound 9 which exhibits excellent in vitro activity, desirable pharmacokinetic parameters and good efficacy in animal models of bronchoconstriction." @default.
• W2128232386 created "2016-06-24" @default.
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• W2128232386 date "2003-06-01" @default.
• W2128232386 modified "2023-10-09" @default.
• W2128232386 title "Substituted 2-Pyridinemethanol derivatives as potent and selective phosphodiesterase-4 inhibitors" @default.
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• W2128232386 doi "https://doi.org/10.1016/s0960-894x(03)00314-7" @default.
• W2128232386 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12749899" @default.
• W2128232386 hasPublicationYear "2003" @default.
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