FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2128233866> ?p ?o ?g. }

• W2128233866 endingPage "677" @default.
• W2128233866 startingPage "670" @default.
• W2128233866 abstract "Background. The role of cardiovascular factors in predicting renal outcome has not been extensively elucidated. Herein, we report a prospective evaluation of the impact of left ventricular hypertrophy (LVH) on outcome in non-diabetic patients with chronic kidney disease (CKD). Methods. We studied 144 patients (99 men; age 62 ± 14 years) with stage 3–4 CKD, with baseline assessment of left ventricular mass index (LVMi) by echocardiography, estimated glomerular filtration rate (eGFR) by MDRD equation, 24-h blood pressure profile and 24-h proteinuria. Combined end point was progression to ESRD requiring dialysis, or death within 5 years. Results. Forty-nine patients (34%) progressed to dialysis, 24 (17%) died, 57 (39%) were dialysis-free after 5 years and 14 were lost to follow-up. Multivariate Cox proportional hazards analysis showed that increased LVMi (HR 1.28, 95% CI 1.17–1.40 for each 10-g/m2 increase, P < 0.0001) and reduced eGFR (5% risk increase for each 1-mL/min reduction, P = 0.027) were the significant predictors of the combined end point in stage 3 CKD patients, whereas LVMi proved to be the only significant predictor of the combined end point in patients with stage 4 CKD (HR 1.19, 95% CI 1.09–1.31, P < 0.0001). The same analysis showed that LVMi was the only significant predictor of progression to dialysis in stage 3 CKD patients (HR 1.42, 95% CI 1.23–1.64 for each 10-g/m2 increase, P < 0.0001), while a 20% increase in the risk of progression to ESRD was observed for each 10-g/m2 increase in LVMi (P < 0.0001), and a 10% increase for each 1-mL/min reduction in eGFR (P = 0.046) in patients with stage 4 CKD. When evaluating the predictive role of LVMi on outcome using AUC-ROC curves, the overall performance of the model including LVMi (AUC 0.877, 95% CI 0.8–0.954) was superior to the model including eGFR (AUC 0.737, 95% CI 0.656–0.817) for the end point of progression to dialysis (P = 0.026, Hanley test). Conclusions. LVH proved to be the strongest predictor of the risk of progression to dialysis in non-diabetic CKD, especially among patients with less advanced renal dysfunction. Regardless of whether it is a simple marker or a pathogenetic factor, LVH encompasses all factors possibly affecting renal and general outcome in CKD patients." @default.
• W2128233866 created "2016-06-24" @default.
• W2128233866 creator A5000938189 @default.
• W2128233866 creator A5045507293 @default.
• W2128233866 creator A5051341850 @default.
• W2128233866 creator A5076201267 @default.
• W2128233866 creator A5079361114 @default.
• W2128233866 creator A5090132495 @default.
• W2128233866 date "2010-07-13" @default.
• W2128233866 modified "2023-10-16" @default.
• W2128233866 title "Is left ventricular hypertrophy a powerful predictor of progression to dialysis in chronic kidney disease?" @default.
• W2128233866 cites W188412074 @default.
• W2128233866 cites W1965899716 @default.
• W2128233866 cites W1967297756 @default.
• W2128233866 cites W1996902731 @default.
• W2128233866 cites W1999648128 @default.
• W2128233866 cites W2012152951 @default.
• W2128233866 cites W2035822743 @default.
• W2128233866 cites W2042293234 @default.
• W2128233866 cites W2045516356 @default.
• W2128233866 cites W2053116647 @default.
• W2128233866 cites W2057275427 @default.
• W2128233866 cites W2077100307 @default.
• W2128233866 cites W2079901425 @default.
• W2128233866 cites W2091886687 @default.
• W2128233866 cites W2096073058 @default.
• W2128233866 cites W2096607633 @default.
• W2128233866 cites W2097595842 @default.
• W2128233866 cites W2099698952 @default.
• W2128233866 cites W2103868761 @default.
• W2128233866 cites W2114720788 @default.
• W2128233866 cites W2121969402 @default.
• W2128233866 cites W2130827265 @default.
• W2128233866 cites W2136557329 @default.
• W2128233866 cites W2136704054 @default.
• W2128233866 cites W2159843374 @default.
• W2128233866 cites W2169521769 @default.
• W2128233866 cites W2169588753 @default.
• W2128233866 cites W2169687778 @default.
• W2128233866 cites W2170810459 @default.
• W2128233866 cites W2334499091 @default.
• W2128233866 doi "https://doi.org/10.1093/ndt/gfq409" @default.
• W2128233866 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20628183" @default.
• W2128233866 hasPublicationYear "2010" @default.
• W2128233866 type Work @default.
• W2128233866 sameAs 2128233866 @default.
• W2128233866 citedByCount "37" @default.
• W2128233866 countsByYear W21282338662012 @default.
• W2128233866 countsByYear W21282338662013 @default.
• W2128233866 countsByYear W21282338662014 @default.
• W2128233866 countsByYear W21282338662015 @default.
• W2128233866 countsByYear W21282338662017 @default.
• W2128233866 countsByYear W21282338662018 @default.
• W2128233866 countsByYear W21282338662019 @default.
• W2128233866 countsByYear W21282338662021 @default.
• W2128233866 countsByYear W21282338662022 @default.
• W2128233866 countsByYear W21282338662023 @default.
• W2128233866 crossrefType "journal-article" @default.
• W2128233866 hasAuthorship W2128233866A5000938189 @default.
• W2128233866 hasAuthorship W2128233866A5045507293 @default.
• W2128233866 hasAuthorship W2128233866A5051341850 @default.
• W2128233866 hasAuthorship W2128233866A5076201267 @default.
• W2128233866 hasAuthorship W2128233866A5079361114 @default.
• W2128233866 hasAuthorship W2128233866A5090132495 @default.
• W2128233866 hasConcept C126322002 @default.
• W2128233866 hasConcept C159641895 @default.
• W2128233866 hasConcept C164705383 @default.
• W2128233866 hasConcept C167414201 @default.
• W2128233866 hasConcept C188816634 @default.
• W2128233866 hasConcept C2776002628 @default.
• W2128233866 hasConcept C2778063415 @default.
• W2128233866 hasConcept C2778653478 @default.
• W2128233866 hasConcept C2779561371 @default.
• W2128233866 hasConcept C2779978075 @default.
• W2128233866 hasConcept C2780091579 @default.
• W2128233866 hasConcept C3019040382 @default.
• W2128233866 hasConcept C50382708 @default.
• W2128233866 hasConcept C71924100 @default.
• W2128233866 hasConcept C84393581 @default.
• W2128233866 hasConceptScore W2128233866C126322002 @default.
• W2128233866 hasConceptScore W2128233866C159641895 @default.
• W2128233866 hasConceptScore W2128233866C164705383 @default.
• W2128233866 hasConceptScore W2128233866C167414201 @default.
• W2128233866 hasConceptScore W2128233866C188816634 @default.
• W2128233866 hasConceptScore W2128233866C2776002628 @default.
• W2128233866 hasConceptScore W2128233866C2778063415 @default.
• W2128233866 hasConceptScore W2128233866C2778653478 @default.
• W2128233866 hasConceptScore W2128233866C2779561371 @default.
• W2128233866 hasConceptScore W2128233866C2779978075 @default.
• W2128233866 hasConceptScore W2128233866C2780091579 @default.
• W2128233866 hasConceptScore W2128233866C3019040382 @default.
• W2128233866 hasConceptScore W2128233866C50382708 @default.
• W2128233866 hasConceptScore W2128233866C71924100 @default.
• W2128233866 hasConceptScore W2128233866C84393581 @default.
• W2128233866 hasIssue "2" @default.
• W2128233866 hasLocation W21282338661 @default.
• W2128233866 hasLocation W21282338662 @default.
• W2128233866 hasOpenAccess W2128233866 @default.

• next