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W2128431303 abstract "To evaluate potential risk factors and protective factors for acute diarrheal disease in urban infants, 500 infants < or = 12 months old with diarrhea and 500 age-matched control subjects coming to a São Paulo emergency room were studied. On multivariate analysis, these apparently sporadic community-acquired cases of diarrhea were significantly associated with hospitalization in the month before onset (odds ratio [OR], 3.4), day care center exposure (OR, 2.0), prior diarrhea in another household member (OR, 4.4), and low family income (OR, 1.8). Breast-feeding infants < 6 months old (OR, 0.3) and boiling household drinking water (OR, 0.4) were protective. Enteropathogenic Escherichia coli (EPEC; OR, 12.0) and Salmonella (OR, 7/0, discordant pairs) infections were associated with prior hospitalization, rotavirus infections were associated with day care (OR, 6/0), and breast-feeding was protective against EPEC infections (OR, 0.1). These results suggest that certain preventive strategies can prevent a substantial proportion of cases of diarrheal disease in Brazilian infants." @default.
W2128431303 created "2016-06-24" @default.
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W2128431303 date "1993-03-01" @default.
W2128431303 modified "2023-10-16" @default.
W2128431303 title "Pathogen-Specific Risk Factors and Protective Factors for Acute Diarrheal Disease in Urban Brazilian Infants" @default.
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W2128431303 doi "https://doi.org/10.1093/infdis/167.3.627" @default.
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