Matches in SemOpenAlex for { <https://semopenalex.org/work/W2128570908> ?p ?o ?g. }
Showing items 1 to 76 of
76
with 100 items per page.
- W2128570908 endingPage "562" @default.
- W2128570908 startingPage "562" @default.
- W2128570908 abstract "Previous results have shown tissue constriction in allergic animals following inhalation of an antigen. Further studies have demonstrated a differing response pattern in airway and parenchymal mechanics following inhaled (i.h.) or intravenous (i.v.) delivery of methacholine (MCh).The purpose of this study was to compare the acute allergic response in airway and parenchymal mechanics following i.h. and i.v. antigen challenge.Brown Norway rats were sensitized to ovalbumin (OVA). Rats were anaesthetized, paralysed, and thoracotomized, and lung input impedance (ZL) between 0.5 and 21 Hz was measured using small-amplitude pseudo-random oscillations at control, after saline, and for up to 1 h after either i.h. (n = 7) or i.v. (n = 5) administration of OVA. ZL was evaluated in terms of airway resistance (Raw) and inertance (Iaw), and a constant phase tissue parenchymal damping (G) and elastance (H).Following i.h. OVA challenge elevations were found in Raw [192 +/- 32 (SE) %], G (223 +/- 21%), and H (141 +/- 5%). Raw showed higher elevation after i.v. challenge (418 +/- 57%), whereas the elevation in G (278 +/- 30%) and H (130 +/- 4%) was approximately equal to those seen following inhalation of an antigen.Delivery (i.v.) of an antigen produces a significantly higher response in airway resistance, whereas inhaled antigen results in a mixed airway and parenchymal response." @default.
- W2128570908 created "2016-06-24" @default.
- W2128570908 creator A5011167300 @default.
- W2128570908 creator A5013191639 @default.
- W2128570908 creator A5048175603 @default.
- W2128570908 creator A5078348407 @default.
- W2128570908 date "1999-01-01" @default.
- W2128570908 modified "2023-10-16" @default.
- W2128570908 title "The route of antigen delivery determines the airway and lung tissue mechanical responses in allergic rats" @default.
- W2128570908 doi "https://doi.org/10.1046/j.1365-2222.1999.00471.x" @default.
- W2128570908 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10202372" @default.
- W2128570908 hasPublicationYear "1999" @default.
- W2128570908 type Work @default.
- W2128570908 sameAs 2128570908 @default.
- W2128570908 citedByCount "19" @default.
- W2128570908 countsByYear W21285709082012 @default.
- W2128570908 countsByYear W21285709082013 @default.
- W2128570908 crossrefType "journal-article" @default.
- W2128570908 hasAuthorship W2128570908A5011167300 @default.
- W2128570908 hasAuthorship W2128570908A5013191639 @default.
- W2128570908 hasAuthorship W2128570908A5048175603 @default.
- W2128570908 hasAuthorship W2128570908A5078348407 @default.
- W2128570908 hasConcept C105922876 @default.
- W2128570908 hasConcept C126322002 @default.
- W2128570908 hasConcept C142724271 @default.
- W2128570908 hasConcept C147483822 @default.
- W2128570908 hasConcept C185592680 @default.
- W2128570908 hasConcept C196822366 @default.
- W2128570908 hasConcept C203014093 @default.
- W2128570908 hasConcept C2776178081 @default.
- W2128570908 hasConcept C2776946954 @default.
- W2128570908 hasConcept C2776954882 @default.
- W2128570908 hasConcept C2777714996 @default.
- W2128570908 hasConcept C2780769369 @default.
- W2128570908 hasConcept C2781260171 @default.
- W2128570908 hasConcept C33362165 @default.
- W2128570908 hasConcept C42219234 @default.
- W2128570908 hasConcept C71924100 @default.
- W2128570908 hasConceptScore W2128570908C105922876 @default.
- W2128570908 hasConceptScore W2128570908C126322002 @default.
- W2128570908 hasConceptScore W2128570908C142724271 @default.
- W2128570908 hasConceptScore W2128570908C147483822 @default.
- W2128570908 hasConceptScore W2128570908C185592680 @default.
- W2128570908 hasConceptScore W2128570908C196822366 @default.
- W2128570908 hasConceptScore W2128570908C203014093 @default.
- W2128570908 hasConceptScore W2128570908C2776178081 @default.
- W2128570908 hasConceptScore W2128570908C2776946954 @default.
- W2128570908 hasConceptScore W2128570908C2776954882 @default.
- W2128570908 hasConceptScore W2128570908C2777714996 @default.
- W2128570908 hasConceptScore W2128570908C2780769369 @default.
- W2128570908 hasConceptScore W2128570908C2781260171 @default.
- W2128570908 hasConceptScore W2128570908C33362165 @default.
- W2128570908 hasConceptScore W2128570908C42219234 @default.
- W2128570908 hasConceptScore W2128570908C71924100 @default.
- W2128570908 hasIssue "4" @default.
- W2128570908 hasLocation W21285709081 @default.
- W2128570908 hasLocation W21285709082 @default.
- W2128570908 hasOpenAccess W2128570908 @default.
- W2128570908 hasPrimaryLocation W21285709081 @default.
- W2128570908 hasRelatedWork W1965683748 @default.
- W2128570908 hasRelatedWork W1973939217 @default.
- W2128570908 hasRelatedWork W2227216773 @default.
- W2128570908 hasRelatedWork W2264996485 @default.
- W2128570908 hasRelatedWork W2380235538 @default.
- W2128570908 hasRelatedWork W2412313190 @default.
- W2128570908 hasRelatedWork W2414095837 @default.
- W2128570908 hasRelatedWork W2940476409 @default.
- W2128570908 hasRelatedWork W3197079515 @default.
- W2128570908 hasRelatedWork W984971617 @default.
- W2128570908 hasVolume "29" @default.
- W2128570908 isParatext "false" @default.
- W2128570908 isRetracted "false" @default.
- W2128570908 magId "2128570908" @default.
- W2128570908 workType "article" @default.