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- W2128571130 endingPage "1072" @default.
- W2128571130 startingPage "1063" @default.
- W2128571130 abstract "Some of the most devastating oomycete pathogens deploy effector proteins, with the signature amino acid motif RXLR, that enter plant cells to promote virulence. Research on the function and evolution of RXLR effectors has been very active over the decade that has transpired since their discovery. Comparative genomics indicate that RXLR genes play a major role in virulence for Phytophthora and downy mildew species. Importantly, gene-for-gene resistance against these oomycete lineages is based on recognition of RXLR proteins. Comparative genomics have revealed several mechanisms through which this resistance can be broken, most notably involving epigenetic control of RXLR gene expression. Structural studies have revealed a core fold that is present in the majority of RXLR proteins, providing a foundation for detailed mechanistic understanding of virulence and avirulence functions. Finally, functional studies have demonstrated that suppression of host immunity is a major function for RXLR proteins. Host protein targets are being identified in a variety of plant cell compartments. Some targets comprise hubs that are also manipulated by bacteria and fungi, thereby revealing key points of vulnerability in the plant immune network." @default.
- W2128571130 created "2016-06-24" @default.
- W2128571130 creator A5015837360 @default.
- W2128571130 creator A5030970741 @default.
- W2128571130 creator A5035379146 @default.
- W2128571130 creator A5089084257 @default.
- W2128571130 date "2015-10-01" @default.
- W2128571130 modified "2023-10-11" @default.
- W2128571130 title "Recent Progress in RXLR Effector Research" @default.
- W2128571130 cites W1571269646 @default.
- W2128571130 cites W1839095954 @default.
- W2128571130 cites W1891876658 @default.
- W2128571130 cites W1940875128 @default.
- W2128571130 cites W1964160457 @default.
- W2128571130 cites W1965320478 @default.
- W2128571130 cites W1968004483 @default.
- W2128571130 cites W1969024533 @default.
- W2128571130 cites W1969497597 @default.
- W2128571130 cites W1969726504 @default.
- W2128571130 cites W1969966687 @default.
- W2128571130 cites W1972895163 @default.
- W2128571130 cites W1973573308 @default.
- W2128571130 cites W1974182935 @default.
- W2128571130 cites W1974330585 @default.
- W2128571130 cites W1983690863 @default.
- W2128571130 cites W1991755232 @default.
- W2128571130 cites W1992669603 @default.
- W2128571130 cites W1993671611 @default.
- W2128571130 cites W1994155714 @default.
- W2128571130 cites W1994274943 @default.
- W2128571130 cites W1996014015 @default.
- W2128571130 cites W1996766766 @default.
- W2128571130 cites W1997713745 @default.
- W2128571130 cites W2000071580 @default.
- W2128571130 cites W2000821899 @default.
- W2128571130 cites W2009649462 @default.
- W2128571130 cites W2012701671 @default.
- W2128571130 cites W2014333453 @default.
- W2128571130 cites W2017048824 @default.
- W2128571130 cites W2018812254 @default.
- W2128571130 cites W2026936889 @default.
- W2128571130 cites W2027367097 @default.
- W2128571130 cites W2029835563 @default.
- W2128571130 cites W2030146975 @default.
- W2128571130 cites W2030350258 @default.
- W2128571130 cites W2031120459 @default.
- W2128571130 cites W2034374114 @default.
- W2128571130 cites W2035129085 @default.
- W2128571130 cites W2038463428 @default.
- W2128571130 cites W2039278889 @default.
- W2128571130 cites W2039634837 @default.
- W2128571130 cites W2039734541 @default.
- W2128571130 cites W2041136465 @default.
- W2128571130 cites W2043676058 @default.
- W2128571130 cites W2053317081 @default.
- W2128571130 cites W2054562396 @default.
- W2128571130 cites W2058896934 @default.
- W2128571130 cites W2062319002 @default.
- W2128571130 cites W2065654765 @default.
- W2128571130 cites W2066002777 @default.
- W2128571130 cites W2067247089 @default.
- W2128571130 cites W2067327084 @default.
- W2128571130 cites W2067761947 @default.
- W2128571130 cites W2068746016 @default.
- W2128571130 cites W2070284343 @default.
- W2128571130 cites W207186185 @default.
- W2128571130 cites W2073430724 @default.
- W2128571130 cites W2074125429 @default.
- W2128571130 cites W2075997754 @default.
- W2128571130 cites W2077720900 @default.
- W2128571130 cites W2083873210 @default.
- W2128571130 cites W2085140290 @default.
- W2128571130 cites W2089762842 @default.
- W2128571130 cites W2090286421 @default.
- W2128571130 cites W2090595780 @default.
- W2128571130 cites W2093745128 @default.
- W2128571130 cites W2095912397 @default.
- W2128571130 cites W2096242878 @default.
- W2128571130 cites W2098669490 @default.
- W2128571130 cites W2099507355 @default.
- W2128571130 cites W2100001046 @default.
- W2128571130 cites W2101000074 @default.
- W2128571130 cites W2102370923 @default.
- W2128571130 cites W2103574752 @default.
- W2128571130 cites W2106744560 @default.
- W2128571130 cites W2107013677 @default.
- W2128571130 cites W2110002140 @default.
- W2128571130 cites W2110785772 @default.
- W2128571130 cites W2112731187 @default.
- W2128571130 cites W2119609114 @default.
- W2128571130 cites W2119842047 @default.
- W2128571130 cites W2120867442 @default.
- W2128571130 cites W2123389767 @default.
- W2128571130 cites W2123480403 @default.
- W2128571130 cites W2123606651 @default.
- W2128571130 cites W2126498993 @default.
- W2128571130 cites W2130497254 @default.
- W2128571130 cites W2132671821 @default.