FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2128576488> ?p ?o ?g. }

• W2128576488 endingPage "3394" @default.
• W2128576488 startingPage "3385" @default.
• W2128576488 abstract "ABSTRACT We have isolated and molecularly characterized the cramped (crm) gene of Drosophila melanogaster, and show that it can be classified as a Polycomb-group (Pc-G) gene. crm mutants exhibit typical Pc-G mutant phenotypes, rem-iniscent of ectopic homeotic gene expression, with additional sex comb teeth found on mesothoracic and meta-thoracic legs, and proximodistal transformations of the tarsal segments. crm encodes an 693 amino acids protein, with no significant homology to known proteins. We used polyclonal antibodies raised against bacterially expressed truncated CRM protein to show that the crm gene product is localized to the nucleus during embryogenesis. This nuclear localization appears to be restricted to S-phase nuclei, as CRM immunostaining disappears at mitosis. We found that this cell-cycle-dependent staining pattern was identical to that of Proliferating Cell Nuclear Antigen (PCNA). Further-more, we provide evidence for co-localization of CRM and PCNA proteins in salivary gland polytene nuclei, and for a genetic interaction between crm and mus209, the Drosophila gene encoding PCNA. Together, our data suggest that these two proteins are involved in a common regulatory pathway and highlight possible interactions between Pc-G-mediated silencing and DNA replication in Drosophila." @default.
• W2128576488 created "2016-06-24" @default.
• W2128576488 creator A5043373700 @default.
• W2128576488 creator A5044993033 @default.
• W2128576488 creator A5050819567 @default.
• W2128576488 creator A5060375630 @default.
• W2128576488 creator A5066356595 @default.
• W2128576488 date "1997-09-01" @default.
• W2128576488 modified "2023-10-13" @default.
• W2128576488 title "The <i>cramped</i> gene of <i>Drosophila</i> is a member of the <i>Polycomb</i>-group, and interacts with <i>mus209</i>, the gene encoding Proliferating Cell Nuclear Antigen" @default.
• W2128576488 cites W129013773 @default.
• W2128576488 cites W1469520329 @default.
• W2128576488 cites W1482000202 @default.
• W2128576488 cites W1504478980 @default.
• W2128576488 cites W1509979785 @default.
• W2128576488 cites W1746628704 @default.
• W2128576488 cites W1855977133 @default.
• W2128576488 cites W1882251974 @default.
• W2128576488 cites W1908345703 @default.
• W2128576488 cites W1941884118 @default.
• W2128576488 cites W1961475738 @default.
• W2128576488 cites W1969484485 @default.
• W2128576488 cites W1972928782 @default.
• W2128576488 cites W1973449779 @default.
• W2128576488 cites W1978395898 @default.
• W2128576488 cites W1990634134 @default.
• W2128576488 cites W1997731188 @default.
• W2128576488 cites W2006922495 @default.
• W2128576488 cites W2009851083 @default.
• W2128576488 cites W2011192730 @default.
• W2128576488 cites W2011962025 @default.
• W2128576488 cites W2015446431 @default.
• W2128576488 cites W2019772204 @default.
• W2128576488 cites W2022236187 @default.
• W2128576488 cites W2024615596 @default.
• W2128576488 cites W2027657247 @default.
• W2128576488 cites W2031204518 @default.
• W2128576488 cites W2040051622 @default.
• W2128576488 cites W2046140706 @default.
• W2128576488 cites W2047724514 @default.
• W2128576488 cites W2052143241 @default.
• W2128576488 cites W2053803579 @default.
• W2128576488 cites W2055261987 @default.
• W2128576488 cites W2058691714 @default.
• W2128576488 cites W2059696301 @default.
• W2128576488 cites W2079739354 @default.
• W2128576488 cites W2080719230 @default.
• W2128576488 cites W2100634503 @default.
• W2128576488 cites W2100837269 @default.
• W2128576488 cites W2103080800 @default.
• W2128576488 cites W2105704892 @default.
• W2128576488 cites W2120021898 @default.
• W2128576488 cites W2122380132 @default.
• W2128576488 cites W2129089556 @default.
• W2128576488 cites W2134019256 @default.
• W2128576488 cites W2161248275 @default.
• W2128576488 cites W2257153740 @default.
• W2128576488 cites W2283381656 @default.
• W2128576488 cites W2374212811 @default.
• W2128576488 cites W334893080 @default.
• W2128576488 cites W33805216 @default.
• W2128576488 cites W4233723707 @default.
• W2128576488 cites W4254829742 @default.
• W2128576488 doi "https://doi.org/10.1242/dev.124.17.3385" @default.
• W2128576488 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9310333" @default.
• W2128576488 hasPublicationYear "1997" @default.
• W2128576488 type Work @default.
• W2128576488 sameAs 2128576488 @default.
• W2128576488 citedByCount "60" @default.
• W2128576488 countsByYear W21285764882012 @default.
• W2128576488 countsByYear W21285764882015 @default.
• W2128576488 countsByYear W21285764882017 @default.
• W2128576488 countsByYear W21285764882018 @default.
• W2128576488 countsByYear W21285764882020 @default.
• W2128576488 crossrefType "journal-article" @default.
• W2128576488 hasAuthorship W2128576488A5043373700 @default.
• W2128576488 hasAuthorship W2128576488A5044993033 @default.
• W2128576488 hasAuthorship W2128576488A5050819567 @default.
• W2128576488 hasAuthorship W2128576488A5060375630 @default.
• W2128576488 hasAuthorship W2128576488A5066356595 @default.
• W2128576488 hasConcept C104317684 @default.
• W2128576488 hasConcept C143065580 @default.
• W2128576488 hasConcept C150194340 @default.
• W2128576488 hasConcept C153911025 @default.
• W2128576488 hasConcept C195286587 @default.
• W2128576488 hasConcept C2780104201 @default.
• W2128576488 hasConcept C29512474 @default.
• W2128576488 hasConcept C34688535 @default.
• W2128576488 hasConcept C49805395 @default.
• W2128576488 hasConcept C51423104 @default.
• W2128576488 hasConcept C54355233 @default.
• W2128576488 hasConcept C552990157 @default.
• W2128576488 hasConcept C86339819 @default.
• W2128576488 hasConcept C86803240 @default.
• W2128576488 hasConcept C93304396 @default.
• W2128576488 hasConcept C95444343 @default.
• W2128576488 hasConceptScore W2128576488C104317684 @default.
• W2128576488 hasConceptScore W2128576488C143065580 @default.

• next