Matches in SemOpenAlex for { <https://semopenalex.org/work/W2128596144> ?p ?o ?g. }
Showing items 1 to 65 of
65
with 100 items per page.
- W2128596144 endingPage "5301" @default.
- W2128596144 startingPage "5296" @default.
- W2128596144 abstract "Formation of bone outside the skeletal system which can occur in all kinds of soft tissues is called Ectopic or Heterotopic Ossification (HO). It is the abnormal formation of true bone within extra skeletal soft tissues. The TGF-β super family several physiological processes are mediate by these polypeptides such as regulates bone formation and resorption as well as osteoclasts differentiation and survival is stimulated by them. Total of 21 head injured patients admitted in the hospital between 8 to 33 years old. All individuals are treated with indomethacin to control HO formation. The red light treatment and heat lamp exposure were done for 20 min in each day of physiotherapy. Both effective members of transforming growth factor- β, superfamily were analyzed by molecular mechanic methods in amber force field. Montecarlo simulation was done for 200 pSec and the ψ, φ angles of each amino acids were calculated. Clinically, of 25 potentially relevant records identified, 21 were related to HO. Following the treatment, 11 individuals showed the response to heat exposure and physical exercises. 9 out of 21 not only never do effective response to heat treatment, but also progress the HO formation. The results reveal that 2 tgi tends to arrange the protein critical angels of φ and ψ, into more favored and/ or allowed region and the formation and development of right handed, left handed α- helices and β- pleated sheath will be more facilitated because of rising in temperature. It is suggested that this phenomenon cause 2tgi to act in a better thermodynamic situation. Key words: Ramachandran plot, Montecarlo simulation ectopic bone formation, transforming growth factor- β; 1tfg; 2tgi." @default.
- W2128596144 created "2016-06-24" @default.
- W2128596144 creator A5006655505 @default.
- W2128596144 date "2011-10-30" @default.
- W2128596144 modified "2023-09-24" @default.
- W2128596144 title "Clinically relevance of ectopic bone formation to the structure of TGF- β superfamily in stress condition" @default.
- W2128596144 cites W1964745823 @default.
- W2128596144 cites W1990270102 @default.
- W2128596144 cites W1992407302 @default.
- W2128596144 cites W1999973395 @default.
- W2128596144 cites W2000011999 @default.
- W2128596144 cites W2013263444 @default.
- W2128596144 cites W2016417749 @default.
- W2128596144 cites W2028527142 @default.
- W2128596144 cites W2057698298 @default.
- W2128596144 cites W2072273255 @default.
- W2128596144 cites W2093654042 @default.
- W2128596144 cites W2097651262 @default.
- W2128596144 cites W2107034917 @default.
- W2128596144 cites W2113704955 @default.
- W2128596144 cites W2123010250 @default.
- W2128596144 cites W2158707966 @default.
- W2128596144 cites W2159999899 @default.
- W2128596144 cites W2474630207 @default.
- W2128596144 cites W52791704 @default.
- W2128596144 doi "https://doi.org/10.5897/sre11.1414" @default.
- W2128596144 hasPublicationYear "2011" @default.
- W2128596144 type Work @default.
- W2128596144 sameAs 2128596144 @default.
- W2128596144 citedByCount "0" @default.
- W2128596144 crossrefType "journal-article" @default.
- W2128596144 hasAuthorship W2128596144A5006655505 @default.
- W2128596144 hasConcept C118131993 @default.
- W2128596144 hasConcept C126322002 @default.
- W2128596144 hasConcept C141071460 @default.
- W2128596144 hasConcept C146562846 @default.
- W2128596144 hasConcept C185592680 @default.
- W2128596144 hasConcept C2778842504 @default.
- W2128596144 hasConcept C2780650075 @default.
- W2128596144 hasConcept C2993291840 @default.
- W2128596144 hasConcept C673006 @default.
- W2128596144 hasConcept C71924100 @default.
- W2128596144 hasConceptScore W2128596144C118131993 @default.
- W2128596144 hasConceptScore W2128596144C126322002 @default.
- W2128596144 hasConceptScore W2128596144C141071460 @default.
- W2128596144 hasConceptScore W2128596144C146562846 @default.
- W2128596144 hasConceptScore W2128596144C185592680 @default.
- W2128596144 hasConceptScore W2128596144C2778842504 @default.
- W2128596144 hasConceptScore W2128596144C2780650075 @default.
- W2128596144 hasConceptScore W2128596144C2993291840 @default.
- W2128596144 hasConceptScore W2128596144C673006 @default.
- W2128596144 hasConceptScore W2128596144C71924100 @default.
- W2128596144 hasIssue "25" @default.
- W2128596144 hasLocation W21285961441 @default.
- W2128596144 hasOpenAccess W2128596144 @default.
- W2128596144 hasPrimaryLocation W21285961441 @default.
- W2128596144 hasRelatedWork W3107457690 @default.
- W2128596144 hasRelatedWork W2185717927 @default.
- W2128596144 hasVolume "6" @default.
- W2128596144 isParatext "false" @default.
- W2128596144 isRetracted "false" @default.
- W2128596144 magId "2128596144" @default.
- W2128596144 workType "article" @default.