FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2128648765> ?p ?o ?g. }

• W2128648765 endingPage "58" @default.
• W2128648765 startingPage "46" @default.
• W2128648765 abstract "Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infection (LRTI) in infants and young children, accounting for approximately 75,000-125,000 hospitalizations per year. It is estimated that in 2000, RSV infection accounted for 1.7 million office visits, 402,000 emergency room visits, and 236,000 hospital outpatient visits per year for children younger than 5 years of age. Palivizumab, a humanized monoclonal antibody directed against RSV, is the only immunoprophylaxis therapy approved by the FDA for prevention of serious lower respiratory tract disease caused by RSV in infants (up to 2 years of age) who meet 1 or more of the following criteria for high risk: (a) gestational age up to 35 weeks;(b) diagnosis of chronic lung disease (CLD, formerly bronchopulmonary dysplasia [BPD]); or (c) diagnosis of cyanotic or complex congenital heart disease. The RSV season typically occurs between November and March but may vary by region. During the period of our review, depending on local duration of the RSV season, infants usually required 5 monthly (every 28-30 days) intramuscular injections of palivizumab. Infants born in the middle of the season received their palivizumab doses from the time of birth to the end of the season and, therefore, may have required less than 5 doses.It is unclear if compliance with monthly doses is a problem and whether noncompliance increases the risk of RSV hospitalizations in routine clinical practice.To (a) identify and describe compliance rates and the factors that influence parental compliance with immunoprophylaxis regimens, (b)review intervention programs and describe those that have been associated with increased compliance, and (c) summarize the association of compliance with RSV hospitalization rates.An electronic literature search was conducted using journal databases, including Ovid, Current Contents, Embase, Medline In-Process & Other Non-Indexed Citations; Ovid Medline, PubMed, and Web of Science;and an abstract database, Medical Intelligence Solution, for citations through April 2008. Specific search terms used were palivizumab with patient compliance, patient adherence, or patient persistence.Twenty-five articles and abstracts met the inclusion criteria. Available studies were mostly retrospective or observational prospective.Compliance, defined in various ways across the studies, varied between 25% and 100%, and 12 studies identified some of the factors related to noncompliance. Compliance generally was lower among Medicaid patients,African American patients, and other minorities. Ten studies (3 manuscripts and 7 abstracts) investigated the association of administration of prophylaxis through monthly home visits by a health professional with parental compliance with therapy. Most of the home-based programs were associated with higher compliance rates compared with clinic or office programs.Rates as high as 94% and 64% were achieved when Medicaid infants and infants of minority descent, respectively, received their doses through a home health program. When these infants received their doses at a clinic or office, depending on the definition of compliance, rates were 61%-100% for Medicaid infants and 44% for infants of minority descent. Reminder telephone calls to parents or caregivers, comprehensive multidisciplinary programs that included extensive counseling of parents, calendars with sticker reminders, and education in the language native to parents also were associated with increased compliance, although statistical significance was reported in only 1 study. Several studies recommended educating parents on the benefits of RSV prophylaxis, alleviating transportation and language difficulties, recognizing cultural differences and biases, and clarifying misperception of RSV illness severity. Home health programs had lower rates of RSV hospitalizations than office-based programs in 3 analyses conducted in 2 studies. In 4 other abstracts, the rates of RSV hospitalization for home health programs and office-based administration did not significantly differ. In a large, 4-season, prospective outcome study, compliant infants had lower RSV hospitalization rates than those who were not compliant under one definition of compliance (doses within 35-day intervals). RSV hospitalization rates were not significantly different using another definition of compliance (receipt of anticipated doses, expected vs. observed rates).In a large survey of 10,390 infants identified from pharmacy dispensing records, RSV hospitalization rates were 1.4% in the compliant group versus 3.1% in the noncompliant group (OR = 2.2, 95% CI = 1.4-3.5, P < 0.001).Adjustment for confounding was not reported in these studies.Medicaid and minority infants were less likely to receive scheduled palivizumab doses. Home-based programs for the administration of palivizumab have been investigated more than other interventions and are associated with improved compliance compared with office-based administration. Compliance with dosing, in general, was associated with lower RSV hospitalization rates. However, these strategies should be further investigated using well-designed studies." @default.
• W2128648765 created "2016-06-24" @default.
• W2128648765 creator A5004124227 @default.
• W2128648765 creator A5031724058 @default.
• W2128648765 creator A5033129107 @default.
• W2128648765 creator A5038671951 @default.
• W2128648765 creator A5063143227 @default.
• W2128648765 date "2010-01-01" @default.
• W2128648765 modified "2023-09-25" @default.
• W2128648765 title "A Systematic Review of Compliance with Palivizumab Administration for RSV Immunoprophylaxis" @default.
• W2128648765 cites W1966099212 @default.
• W2128648765 cites W1974757732 @default.
• W2128648765 cites W1983914898 @default.
• W2128648765 cites W2007583880 @default.
• W2128648765 cites W2016056885 @default.
• W2128648765 cites W2018672014 @default.
• W2128648765 cites W2022259512 @default.
• W2128648765 cites W2036877259 @default.
• W2128648765 cites W2058207519 @default.
• W2128648765 cites W2077290707 @default.
• W2128648765 cites W2139841187 @default.
• W2128648765 cites W2156654572 @default.
• W2128648765 cites W2316897460 @default.
• W2128648765 doi "https://doi.org/10.18553/jmcp.2010.16.1.46" @default.
• W2128648765 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20131495" @default.
• W2128648765 hasPublicationYear "2010" @default.
• W2128648765 type Work @default.
• W2128648765 sameAs 2128648765 @default.
• W2128648765 citedByCount "72" @default.
• W2128648765 countsByYear W21286487652012 @default.
• W2128648765 countsByYear W21286487652013 @default.
• W2128648765 countsByYear W21286487652014 @default.
• W2128648765 countsByYear W21286487652015 @default.
• W2128648765 countsByYear W21286487652016 @default.
• W2128648765 countsByYear W21286487652017 @default.
• W2128648765 countsByYear W21286487652018 @default.
• W2128648765 countsByYear W21286487652019 @default.
• W2128648765 countsByYear W21286487652020 @default.
• W2128648765 countsByYear W21286487652021 @default.
• W2128648765 countsByYear W21286487652022 @default.
• W2128648765 countsByYear W21286487652023 @default.
• W2128648765 crossrefType "journal-article" @default.
• W2128648765 hasAuthorship W2128648765A5004124227 @default.
• W2128648765 hasAuthorship W2128648765A5031724058 @default.
• W2128648765 hasAuthorship W2128648765A5033129107 @default.
• W2128648765 hasAuthorship W2128648765A5038671951 @default.
• W2128648765 hasAuthorship W2128648765A5063143227 @default.
• W2128648765 hasConcept C126322002 @default.
• W2128648765 hasConcept C187212893 @default.
• W2128648765 hasConcept C2776012195 @default.
• W2128648765 hasConcept C2776399701 @default.
• W2128648765 hasConcept C2778376644 @default.
• W2128648765 hasConcept C2778644256 @default.
• W2128648765 hasConcept C2778721537 @default.
• W2128648765 hasConcept C2778821649 @default.
• W2128648765 hasConcept C2779134260 @default.
• W2128648765 hasConcept C2779234561 @default.
• W2128648765 hasConcept C534529494 @default.
• W2128648765 hasConcept C54355233 @default.
• W2128648765 hasConcept C71924100 @default.
• W2128648765 hasConcept C86803240 @default.
• W2128648765 hasConceptScore W2128648765C126322002 @default.
• W2128648765 hasConceptScore W2128648765C187212893 @default.
• W2128648765 hasConceptScore W2128648765C2776012195 @default.
• W2128648765 hasConceptScore W2128648765C2776399701 @default.
• W2128648765 hasConceptScore W2128648765C2778376644 @default.
• W2128648765 hasConceptScore W2128648765C2778644256 @default.
• W2128648765 hasConceptScore W2128648765C2778721537 @default.
• W2128648765 hasConceptScore W2128648765C2778821649 @default.
• W2128648765 hasConceptScore W2128648765C2779134260 @default.
• W2128648765 hasConceptScore W2128648765C2779234561 @default.
• W2128648765 hasConceptScore W2128648765C534529494 @default.
• W2128648765 hasConceptScore W2128648765C54355233 @default.
• W2128648765 hasConceptScore W2128648765C71924100 @default.
• W2128648765 hasConceptScore W2128648765C86803240 @default.
• W2128648765 hasIssue "1" @default.
• W2128648765 hasLocation W21286487651 @default.
• W2128648765 hasLocation W21286487652 @default.
• W2128648765 hasOpenAccess W2128648765 @default.
• W2128648765 hasPrimaryLocation W21286487651 @default.
• W2128648765 hasRelatedWork W1977536446 @default.
• W2128648765 hasRelatedWork W1982858040 @default.
• W2128648765 hasRelatedWork W2001093521 @default.
• W2128648765 hasRelatedWork W2034716484 @default.
• W2128648765 hasRelatedWork W2065238287 @default.
• W2128648765 hasRelatedWork W2088217763 @default.
• W2128648765 hasRelatedWork W2406407808 @default.
• W2128648765 hasRelatedWork W2412634366 @default.
• W2128648765 hasRelatedWork W4200191061 @default.
• W2128648765 hasRelatedWork W4284714519 @default.
• W2128648765 hasVolume "16" @default.
• W2128648765 isParatext "false" @default.
• W2128648765 isRetracted "false" @default.
• W2128648765 magId "2128648765" @default.
• W2128648765 workType "article" @default.