FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2128678876> ?p ?o ?g. }

• W2128678876 endingPage "66" @default.
• W2128678876 startingPage "59" @default.
• W2128678876 abstract "Abstract —Dietary ω-3 fatty acids retard coronary atherosclerosis. Previously, we demonstrated that dietary ω-3 fatty acids reduce platelet-derived growth factor (PDGF)-A and PDGF-B mRNA levels in unstimulated, human mononuclear cells (MNCs). In a randomized, investigator-blinded intervention trial, we have now compared the effect of ingestion of 7 g/d ω-3, ω-6, or ω-9 fatty acids for 4 weeks versus no dietary intervention on PDGF-A, PDGF-B, heparin-bound epidermal growth factor (HB-EGF), monocyte chemoattractant protein-1 (MCP-1), and interleukin-10 gene expression in unstimulated MNCs and in monocytes that were adherence-activated ex vivo in a total of 28 volunteers. In unstimulated MNCs, mRNA steady-state levels of PDGF-A, PDGF-B, and MCP-1 were reduced by 25±10%, 31±13%, and 40±14%, respectively, after ω-3 fatty acid ingestion, as assessed by quantitative polymerase chain reaction (all P <0.05). In monocytes that were adherence-activated ex vivo for 4 and 20 hours, mRNA steady-state levels of PDGF-A, PDGF-B, and MCP-1 were reduced by 25±13%, 20±15%, and 30±8%, respectively (all P <0.05). Interleukin-10 and HB-EGF mRNA steady-state levels were not influenced by ω-3 fatty acid ingestion. Expression of all respective mRNAs in control volunteers or in those ingesting ω-6 or ω-9 fatty acids were not altered. We conclude that human gene expression for PDGF-A, PDGF-B, and MCP-1, factors thought relevant to atherosclerosis, is constitutive, is constant, and can be reduced only by dietary ω-3 fatty acids in unstimulated and adherence-activated monocytes." @default.
• W2128678876 created "2016-06-24" @default.
• W2128678876 creator A5018234513 @default.
• W2128678876 creator A5028895212 @default.
• W2128678876 creator A5033733522 @default.
• W2128678876 creator A5035005364 @default.
• W2128678876 creator A5035423861 @default.
• W2128678876 creator A5066764071 @default.
• W2128678876 creator A5075521205 @default.
• W2128678876 date "1999-01-01" @default.
• W2128678876 modified "2023-10-03" @default.
• W2128678876 title "Dietary ω-3, ω-6, and ω-9 Unsaturated Fatty Acids and Growth Factor and Cytokine Gene Expression in Unstimulated and Stimulated Monocytes" @default.
• W2128678876 cites W1517120488 @default.
• W2128678876 cites W1633340712 @default.
• W2128678876 cites W1844068603 @default.
• W2128678876 cites W1906863411 @default.
• W2128678876 cites W1958967044 @default.
• W2128678876 cites W1974172335 @default.
• W2128678876 cites W1975375148 @default.
• W2128678876 cites W1983531379 @default.
• W2128678876 cites W1985382802 @default.
• W2128678876 cites W1987447778 @default.
• W2128678876 cites W2002917252 @default.
• W2128678876 cites W2004657626 @default.
• W2128678876 cites W2011957331 @default.
• W2128678876 cites W2016191021 @default.
• W2128678876 cites W2023124533 @default.
• W2128678876 cites W2038086562 @default.
• W2128678876 cites W2045350909 @default.
• W2128678876 cites W2046066271 @default.
• W2128678876 cites W2055336483 @default.
• W2128678876 cites W2059165131 @default.
• W2128678876 cites W2059618963 @default.
• W2128678876 cites W2068077370 @default.
• W2128678876 cites W2077234593 @default.
• W2128678876 cites W2080689827 @default.
• W2128678876 cites W2090455750 @default.
• W2128678876 cites W2092602709 @default.
• W2128678876 cites W2096041707 @default.
• W2128678876 cites W2101541068 @default.
• W2128678876 cites W2107518586 @default.
• W2128678876 cites W2107928904 @default.
• W2128678876 cites W2118663842 @default.
• W2128678876 cites W2137570167 @default.
• W2128678876 cites W2151426663 @default.
• W2128678876 cites W2234262376 @default.
• W2128678876 cites W2258125836 @default.
• W2128678876 cites W2272317157 @default.
• W2128678876 cites W2287126030 @default.
• W2128678876 cites W2327515496 @default.
• W2128678876 cites W2945251864 @default.
• W2128678876 doi "https://doi.org/10.1161/01.atv.19.1.59" @default.
• W2128678876 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9888867" @default.
• W2128678876 hasPublicationYear "1999" @default.
• W2128678876 type Work @default.
• W2128678876 sameAs 2128678876 @default.
• W2128678876 citedByCount "116" @default.
• W2128678876 countsByYear W21286788762012 @default.
• W2128678876 countsByYear W21286788762013 @default.
• W2128678876 countsByYear W21286788762014 @default.
• W2128678876 countsByYear W21286788762015 @default.
• W2128678876 countsByYear W21286788762016 @default.
• W2128678876 countsByYear W21286788762017 @default.
• W2128678876 countsByYear W21286788762018 @default.
• W2128678876 countsByYear W21286788762020 @default.
• W2128678876 countsByYear W21286788762021 @default.
• W2128678876 countsByYear W21286788762022 @default.
• W2128678876 countsByYear W21286788762023 @default.
• W2128678876 crossrefType "journal-article" @default.
• W2128678876 hasAuthorship W2128678876A5018234513 @default.
• W2128678876 hasAuthorship W2128678876A5028895212 @default.
• W2128678876 hasAuthorship W2128678876A5033733522 @default.
• W2128678876 hasAuthorship W2128678876A5035005364 @default.
• W2128678876 hasAuthorship W2128678876A5035423861 @default.
• W2128678876 hasAuthorship W2128678876A5066764071 @default.
• W2128678876 hasAuthorship W2128678876A5075521205 @default.
• W2128678876 hasBestOaLocation W21286788761 @default.
• W2128678876 hasConcept C104317684 @default.
• W2128678876 hasConcept C126322002 @default.
• W2128678876 hasConcept C134018914 @default.
• W2128678876 hasConcept C137061746 @default.
• W2128678876 hasConcept C150194340 @default.
• W2128678876 hasConcept C170493617 @default.
• W2128678876 hasConcept C180361614 @default.
• W2128678876 hasConcept C185592680 @default.
• W2128678876 hasConcept C193230392 @default.
• W2128678876 hasConcept C202751555 @default.
• W2128678876 hasConcept C26291073 @default.
• W2128678876 hasConcept C2775960820 @default.
• W2128678876 hasConcept C2776362946 @default.
• W2128678876 hasConcept C2778690821 @default.
• W2128678876 hasConcept C2781184567 @default.
• W2128678876 hasConcept C2781294074 @default.
• W2128678876 hasConcept C543025807 @default.
• W2128678876 hasConcept C55493867 @default.
• W2128678876 hasConcept C71924100 @default.
• W2128678876 hasConcept C86803240 @default.
• W2128678876 hasConceptScore W2128678876C104317684 @default.

• next