FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2128750262> ?p ?o ?g. }

• W2128750262 endingPage "e20376" @default.
• W2128750262 startingPage "e20376" @default.
• W2128750262 abstract "Clostridium perfringens enterotoxin (CPE) is a major virulence factor for human gastrointestinal diseases, such as food poisoning and antibiotic associated diarrhea. The CPE-encoding gene (cpe) can be chromosomal or plasmid-borne. Recent development of conventional PCR cpe-genotyping assays makes it possible to identify cpe location (chromosomal or plasmid) in type A isolates. Initial studies for developing cpe genotyping assays indicated that all cpe-positive strains isolated from sickened patients were typable by cpe-genotypes, but surveys of C. perfringens environmental strains or strains from feces of healthy people suggested that this assay might not be useful for some cpe-carrying type A isolates. In the current study, a pulsed-field gel electrophoresis Southern blot assay showed that four cpe-genotype untypable isolates carried their cpe gene on a plasmid of ∼65 kb. Complete sequence analysis of the ∼65 kb variant cpe-carrying plasmid revealed no intact IS elements and a disrupted cytosine methyltransferase (dcm) gene. More importantly, this plasmid contains a conjugative transfer region, a variant cpe gene and variant iota toxin genes. The toxin genes encoded by this plasmid are expressed based upon the results of RT-PCR assays. The ∼65 kb plasmid is closely related to the pCPF4969 cpe plasmid of type A isolates. MLST analyses indicated these isolates belong to a unique cluster of C. perfringens. Overall, these isolates carrying a variant functional cpe gene and iota toxin genes represent unique type E strains." @default.
• W2128750262 created "2016-06-24" @default.
• W2128750262 creator A5000564606 @default.
• W2128750262 creator A5010898507 @default.
• W2128750262 creator A5070644097 @default.
• W2128750262 creator A5070793093 @default.
• W2128750262 creator A5074119882 @default.
• W2128750262 creator A5088326467 @default.
• W2128750262 creator A5089450547 @default.
• W2128750262 date "2011-05-31" @default.
• W2128750262 modified "2023-09-27" @default.
• W2128750262 title "Identification of Novel Clostridium perfringens Type E Strains That Carry an Iota Toxin Plasmid with a Functional Enterotoxin Gene" @default.
• W2128750262 cites W1966777133 @default.
• W2128750262 cites W1968619706 @default.
• W2128750262 cites W2017817015 @default.
• W2128750262 cites W2022385313 @default.
• W2128750262 cites W2024432852 @default.
• W2128750262 cites W2041848175 @default.
• W2128750262 cites W2064557781 @default.
• W2128750262 cites W2064860971 @default.
• W2128750262 cites W2067496406 @default.
• W2128750262 cites W2089483355 @default.
• W2128750262 cites W2105508603 @default.
• W2128750262 cites W2114196688 @default.
• W2128750262 cites W2117919289 @default.
• W2128750262 cites W2124070339 @default.
• W2128750262 cites W2126028658 @default.
• W2128750262 cites W2127653170 @default.
• W2128750262 cites W2135371566 @default.
• W2128750262 cites W2136842053 @default.
• W2128750262 cites W2145536267 @default.
• W2128750262 cites W2145584773 @default.
• W2128750262 cites W2149062789 @default.
• W2128750262 cites W2156168744 @default.
• W2128750262 cites W2166347193 @default.
• W2128750262 cites W2169071688 @default.
• W2128750262 doi "https://doi.org/10.1371/journal.pone.0020376" @default.
• W2128750262 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3105049" @default.
• W2128750262 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21655254" @default.
• W2128750262 hasPublicationYear "2011" @default.
• W2128750262 type Work @default.
• W2128750262 sameAs 2128750262 @default.
• W2128750262 citedByCount "48" @default.
• W2128750262 countsByYear W21287502622012 @default.
• W2128750262 countsByYear W21287502622013 @default.
• W2128750262 countsByYear W21287502622014 @default.
• W2128750262 countsByYear W21287502622015 @default.
• W2128750262 countsByYear W21287502622016 @default.
• W2128750262 countsByYear W21287502622017 @default.
• W2128750262 countsByYear W21287502622018 @default.
• W2128750262 countsByYear W21287502622019 @default.
• W2128750262 countsByYear W21287502622020 @default.
• W2128750262 countsByYear W21287502622021 @default.
• W2128750262 countsByYear W21287502622022 @default.
• W2128750262 countsByYear W21287502622023 @default.
• W2128750262 crossrefType "journal-article" @default.
• W2128750262 hasAuthorship W2128750262A5000564606 @default.
• W2128750262 hasAuthorship W2128750262A5010898507 @default.
• W2128750262 hasAuthorship W2128750262A5070644097 @default.
• W2128750262 hasAuthorship W2128750262A5070793093 @default.
• W2128750262 hasAuthorship W2128750262A5074119882 @default.
• W2128750262 hasAuthorship W2128750262A5088326467 @default.
• W2128750262 hasAuthorship W2128750262A5089450547 @default.
• W2128750262 hasBestOaLocation W21287502621 @default.
• W2128750262 hasConcept C104317684 @default.
• W2128750262 hasConcept C135763542 @default.
• W2128750262 hasConcept C153911025 @default.
• W2128750262 hasConcept C22744801 @default.
• W2128750262 hasConcept C2777367657 @default.
• W2128750262 hasConcept C2779116991 @default.
• W2128750262 hasConcept C31467283 @default.
• W2128750262 hasConcept C523546767 @default.
• W2128750262 hasConcept C54355233 @default.
• W2128750262 hasConcept C547475151 @default.
• W2128750262 hasConcept C60987743 @default.
• W2128750262 hasConcept C66999527 @default.
• W2128750262 hasConcept C86803240 @default.
• W2128750262 hasConcept C89423630 @default.
• W2128750262 hasConceptScore W2128750262C104317684 @default.
• W2128750262 hasConceptScore W2128750262C135763542 @default.
• W2128750262 hasConceptScore W2128750262C153911025 @default.
• W2128750262 hasConceptScore W2128750262C22744801 @default.
• W2128750262 hasConceptScore W2128750262C2777367657 @default.
• W2128750262 hasConceptScore W2128750262C2779116991 @default.
• W2128750262 hasConceptScore W2128750262C31467283 @default.
• W2128750262 hasConceptScore W2128750262C523546767 @default.
• W2128750262 hasConceptScore W2128750262C54355233 @default.
• W2128750262 hasConceptScore W2128750262C547475151 @default.
• W2128750262 hasConceptScore W2128750262C60987743 @default.
• W2128750262 hasConceptScore W2128750262C66999527 @default.
• W2128750262 hasConceptScore W2128750262C86803240 @default.
• W2128750262 hasConceptScore W2128750262C89423630 @default.
• W2128750262 hasIssue "5" @default.
• W2128750262 hasLocation W21287502621 @default.
• W2128750262 hasLocation W21287502622 @default.
• W2128750262 hasLocation W21287502623 @default.
• W2128750262 hasLocation W21287502624 @default.
• W2128750262 hasLocation W21287502625 @default.

• next