FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2128793295> ?p ?o ?g. }

• W2128793295 endingPage "228" @default.
• W2128793295 startingPage "221" @default.
• W2128793295 abstract "We have designed synthetic peptides corresponding to two different regions of the genome of foot-and-mouth disease virus (FMDV) that are effective as (a) a vaccine or (b) a diagnostic reagent which differentiates convalescent from vaccinated animals, respectively. The peptide vaccine is based on a sequence from the prominent G-H loop of VP1, one of the four capsid proteins. The sequence was optimized by the inclusion of a cyclic constraint and adjoining sequences, and broader immunogenicity was obtained by the incorporation of consensus residues at hypervariable positions. The peptide also included a promiscuous T-helper epitope for effective immunogenicity in outbred populations of large animals.The diagnostic reagent, a peptide based on non-structural (NS) protein 3B, is used in immuno-assays for the detection of antibodies. Antibodies to this NS protein are present in the sera of infected animals but not in the sera of vaccinated animals. The VP1 peptide can be used in complementary immuno-assays for confirmation of NS test results and to monitor for vaccination. This system for differential diagnosis is important to establish the disease-free status of a country." @default.
• W2128793295 created "2016-06-24" @default.
• W2128793295 creator A5005498023 @default.
• W2128793295 creator A5020274628 @default.
• W2128793295 creator A5021688470 @default.
• W2128793295 creator A5025402518 @default.
• W2128793295 creator A5031379744 @default.
• W2128793295 creator A5033758854 @default.
• W2128793295 creator A5042275299 @default.
• W2128793295 creator A5047922016 @default.
• W2128793295 creator A5049422728 @default.
• W2128793295 creator A5053374872 @default.
• W2128793295 creator A5054911839 @default.
• W2128793295 creator A5073091105 @default.
• W2128793295 creator A5075243551 @default.
• W2128793295 creator A5083828440 @default.
• W2128793295 creator A5089330007 @default.
• W2128793295 date "2001-09-01" @default.
• W2128793295 modified "2023-10-14" @default.
• W2128793295 title "Synthetic Peptide-based Vaccine and Diagnostic System for Effective Control of FMD" @default.
• W2128793295 cites W1570128861 @default.
• W2128793295 cites W1990215018 @default.
• W2128793295 cites W2002652947 @default.
• W2128793295 cites W2026719190 @default.
• W2128793295 cites W2032807914 @default.
• W2128793295 cites W2049769525 @default.
• W2128793295 cites W2068966036 @default.
• W2128793295 cites W2158448913 @default.
• W2128793295 cites W2163410014 @default.
• W2128793295 doi "https://doi.org/10.1006/biol.2001.0302" @default.
• W2128793295 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11851319" @default.
• W2128793295 hasPublicationYear "2001" @default.
• W2128793295 type Work @default.
• W2128793295 sameAs 2128793295 @default.
• W2128793295 citedByCount "20" @default.
• W2128793295 countsByYear W21287932952012 @default.
• W2128793295 countsByYear W21287932952014 @default.
• W2128793295 countsByYear W21287932952015 @default.
• W2128793295 countsByYear W21287932952018 @default.
• W2128793295 countsByYear W21287932952020 @default.
• W2128793295 countsByYear W21287932952021 @default.
• W2128793295 crossrefType "journal-article" @default.
• W2128793295 hasAuthorship W2128793295A5005498023 @default.
• W2128793295 hasAuthorship W2128793295A5020274628 @default.
• W2128793295 hasAuthorship W2128793295A5021688470 @default.
• W2128793295 hasAuthorship W2128793295A5025402518 @default.
• W2128793295 hasAuthorship W2128793295A5031379744 @default.
• W2128793295 hasAuthorship W2128793295A5033758854 @default.
• W2128793295 hasAuthorship W2128793295A5042275299 @default.
• W2128793295 hasAuthorship W2128793295A5047922016 @default.
• W2128793295 hasAuthorship W2128793295A5049422728 @default.
• W2128793295 hasAuthorship W2128793295A5053374872 @default.
• W2128793295 hasAuthorship W2128793295A5054911839 @default.
• W2128793295 hasAuthorship W2128793295A5073091105 @default.
• W2128793295 hasAuthorship W2128793295A5075243551 @default.
• W2128793295 hasAuthorship W2128793295A5083828440 @default.
• W2128793295 hasAuthorship W2128793295A5089330007 @default.
• W2128793295 hasConcept C147483822 @default.
• W2128793295 hasConcept C159047783 @default.
• W2128793295 hasConcept C159654299 @default.
• W2128793295 hasConcept C195616568 @default.
• W2128793295 hasConcept C202878990 @default.
• W2128793295 hasConcept C203014093 @default.
• W2128793295 hasConcept C22070199 @default.
• W2128793295 hasConcept C2522874641 @default.
• W2128793295 hasConcept C2776789287 @default.
• W2128793295 hasConcept C2779281246 @default.
• W2128793295 hasConcept C2780868878 @default.
• W2128793295 hasConcept C55493867 @default.
• W2128793295 hasConcept C70721500 @default.
• W2128793295 hasConcept C81566733 @default.
• W2128793295 hasConcept C86803240 @default.
• W2128793295 hasConceptScore W2128793295C147483822 @default.
• W2128793295 hasConceptScore W2128793295C159047783 @default.
• W2128793295 hasConceptScore W2128793295C159654299 @default.
• W2128793295 hasConceptScore W2128793295C195616568 @default.
• W2128793295 hasConceptScore W2128793295C202878990 @default.
• W2128793295 hasConceptScore W2128793295C203014093 @default.
• W2128793295 hasConceptScore W2128793295C22070199 @default.
• W2128793295 hasConceptScore W2128793295C2522874641 @default.
• W2128793295 hasConceptScore W2128793295C2776789287 @default.
• W2128793295 hasConceptScore W2128793295C2779281246 @default.
• W2128793295 hasConceptScore W2128793295C2780868878 @default.
• W2128793295 hasConceptScore W2128793295C55493867 @default.
• W2128793295 hasConceptScore W2128793295C70721500 @default.
• W2128793295 hasConceptScore W2128793295C81566733 @default.
• W2128793295 hasConceptScore W2128793295C86803240 @default.
• W2128793295 hasIssue "3-4" @default.
• W2128793295 hasLocation W21287932951 @default.
• W2128793295 hasLocation W21287932952 @default.
• W2128793295 hasOpenAccess W2128793295 @default.
• W2128793295 hasPrimaryLocation W21287932951 @default.
• W2128793295 hasRelatedWork W1993783049 @default.
• W2128793295 hasRelatedWork W2019183242 @default.
• W2128793295 hasRelatedWork W2075194672 @default.
• W2128793295 hasRelatedWork W2093686365 @default.
• W2128793295 hasRelatedWork W2111743240 @default.
• W2128793295 hasRelatedWork W2217592602 @default.

• next