FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2128859951> ?p ?o ?g. }

• W2128859951 endingPage "367" @default.
• W2128859951 startingPage "367" @default.
• W2128859951 abstract "<h3>Objective</h3> To assess changes in electroretinography (ERG) and other retinal function parameters during 6 months of daily use of tadalafil, sildenafil citrate, or placebo. <h3>Methods</h3> Subjects were randomized to use of a placebo (n = 82), 5 mg of tadalafil (n = 85), or 50 mg of sildenafil (n = 77) daily for 6 months. Electroretinographs were recorded using the International Society for Clinical Electrophysiology of Vision (ISCEV) protocol and standardized ERG equipment at all 15 study sites. Other tests of ocular anatomy and visual function were performed at each assessment. <h3>Main Outcome Measures</h3> The primary outcome was the average mean change for both eyes from baseline to endpoint in ERG b-wave amplitude using dark-adapted combined standard response to a bright ISCEV standard flash. Secondary endpoints were other ERG parameter changes, visual acuity, number of errors in color discrimination testing, mean deviation in automated visual field testing, and intraocular pressure (IOP). <h3>Results</h3> No significant differences were found between treatment/placebo groups for the primary outcome, most other ERG variables, visual function, IOP, or anatomic assessments. The medications were well tolerated. <h3>Conclusions</h3> No abnormalities in ERG or visual function and no treatment-related findings suggestive of drug toxicity are associated with daily administration of tadalafil or sildenafil for 6 months. <h3>Application to Clinical Practice</h3> Assessed visual safety of tadalafil/sildenafil administered daily over a prolonged period. <h3>Trial Registration</h3> clinicaltrials.gov Identifier:NCT00333281" @default.
• W2128859951 created "2016-06-24" @default.
• W2128859951 creator A5010210377 @default.
• W2128859951 creator A5034411688 @default.
• W2128859951 creator A5036422156 @default.
• W2128859951 creator A5042493308 @default.
• W2128859951 creator A5046104318 @default.
• W2128859951 creator A5052411713 @default.
• W2128859951 creator A5054157463 @default.
• W2128859951 creator A5056249618 @default.
• W2128859951 creator A5058142135 @default.
• W2128859951 creator A5078702547 @default.
• W2128859951 creator A5082592591 @default.
• W2128859951 date "2009-04-01" @default.
• W2128859951 modified "2023-10-18" @default.
• W2128859951 title "Retinal Effects of 6 Months of Daily Use of Tadalafil or Sildenafil" @default.
• W2128859951 cites W117237009 @default.
• W2128859951 cites W1513026083 @default.
• W2128859951 cites W1552308041 @default.
• W2128859951 cites W1597890265 @default.
• W2128859951 cites W1924570608 @default.
• W2128859951 cites W1963966604 @default.
• W2128859951 cites W1969692783 @default.
• W2128859951 cites W1970504660 @default.
• W2128859951 cites W1973545783 @default.
• W2128859951 cites W1975119053 @default.
• W2128859951 cites W1979757907 @default.
• W2128859951 cites W1979765238 @default.
• W2128859951 cites W1983781050 @default.
• W2128859951 cites W2001154514 @default.
• W2128859951 cites W200404395 @default.
• W2128859951 cites W2007368614 @default.
• W2128859951 cites W2011257663 @default.
• W2128859951 cites W2013215086 @default.
• W2128859951 cites W2021277443 @default.
• W2128859951 cites W2036671092 @default.
• W2128859951 cites W2037582095 @default.
• W2128859951 cites W2052712306 @default.
• W2128859951 cites W2053426776 @default.
• W2128859951 cites W2057622010 @default.
• W2128859951 cites W2059263687 @default.
• W2128859951 cites W2069922972 @default.
• W2128859951 cites W2140476002 @default.
• W2128859951 cites W2141627140 @default.
• W2128859951 cites W2164468733 @default.
• W2128859951 cites W2317320087 @default.
• W2128859951 doi "https://doi.org/10.1001/archophthalmol.2009.36" @default.
• W2128859951 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19365010" @default.
• W2128859951 hasPublicationYear "2009" @default.
• W2128859951 type Work @default.
• W2128859951 sameAs 2128859951 @default.
• W2128859951 citedByCount "54" @default.
• W2128859951 countsByYear W21288599512012 @default.
• W2128859951 countsByYear W21288599512013 @default.
• W2128859951 countsByYear W21288599512014 @default.
• W2128859951 countsByYear W21288599512015 @default.
• W2128859951 countsByYear W21288599512016 @default.
• W2128859951 countsByYear W21288599512017 @default.
• W2128859951 countsByYear W21288599512018 @default.
• W2128859951 countsByYear W21288599512019 @default.
• W2128859951 countsByYear W21288599512020 @default.
• W2128859951 countsByYear W21288599512021 @default.
• W2128859951 countsByYear W21288599512022 @default.
• W2128859951 countsByYear W21288599512023 @default.
• W2128859951 crossrefType "journal-article" @default.
• W2128859951 hasAuthorship W2128859951A5010210377 @default.
• W2128859951 hasAuthorship W2128859951A5034411688 @default.
• W2128859951 hasAuthorship W2128859951A5036422156 @default.
• W2128859951 hasAuthorship W2128859951A5042493308 @default.
• W2128859951 hasAuthorship W2128859951A5046104318 @default.
• W2128859951 hasAuthorship W2128859951A5052411713 @default.
• W2128859951 hasAuthorship W2128859951A5054157463 @default.
• W2128859951 hasAuthorship W2128859951A5056249618 @default.
• W2128859951 hasAuthorship W2128859951A5058142135 @default.
• W2128859951 hasAuthorship W2128859951A5078702547 @default.
• W2128859951 hasAuthorship W2128859951A5082592591 @default.
• W2128859951 hasConcept C103796816 @default.
• W2128859951 hasConcept C118487528 @default.
• W2128859951 hasConcept C126322002 @default.
• W2128859951 hasConcept C142724271 @default.
• W2128859951 hasConcept C203092338 @default.
• W2128859951 hasConcept C204787440 @default.
• W2128859951 hasConcept C27081682 @default.
• W2128859951 hasConcept C2776768464 @default.
• W2128859951 hasConcept C2778257484 @default.
• W2128859951 hasConcept C2779113765 @default.
• W2128859951 hasConcept C2780816001 @default.
• W2128859951 hasConcept C2780827179 @default.
• W2128859951 hasConcept C535046627 @default.
• W2128859951 hasConcept C71924100 @default.
• W2128859951 hasConcept C7243750 @default.
• W2128859951 hasConceptScore W2128859951C103796816 @default.
• W2128859951 hasConceptScore W2128859951C118487528 @default.
• W2128859951 hasConceptScore W2128859951C126322002 @default.
• W2128859951 hasConceptScore W2128859951C142724271 @default.
• W2128859951 hasConceptScore W2128859951C203092338 @default.
• W2128859951 hasConceptScore W2128859951C204787440 @default.
• W2128859951 hasConceptScore W2128859951C27081682 @default.

• next