FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2128908475> ?p ?o ?g. }

• W2128908475 endingPage "544" @default.
• W2128908475 startingPage "533" @default.
• W2128908475 abstract "Synthesis and transport of mitochondrial proteins were followed in a cell-free homogenate of Neurospora crassa in which mitochondrial translation was inhibited. Proteins synthesized on cytoplasmic ribosomes are transferred into the mitochondrial fraction. The relative amounts of proteins which are transferred in vitro are comparable to those transferred in whole cells. Cycloheximide and puromycin inhibit the synthesis of mitochondrial proteins but not their transfer into mitochondria. The transfer of immunoprecipitable mitochondrial proteins was demonstrated for matrix proteins, carboxyatractyloside-binding protein and cytochrome c. Import of proteins into mitochondria exhibits a degree of specificity. The transport mechanism differentiates between newly synthesized proteins and preexistent mitochondrial proteins, at least in the case of matrix proteins. In the cell-free homogenate membrane-bound ribosomes are more active in the synthesis of mitochondrial proteins than are free ribosomes. The finished translation products appear to be released from the membrane-bound ribosomes into the cytosol rather than into the membrane vesicles. The results suggest that the transport of cytoplasmically synthesized mitochondrial proteins is essentially independent of cytoplasmic translation; that cytoplasmically synthesized mitochondrial proteins exist in an extramitochondrial pool prior to import; that the site of this pool is the cytosol for at least some of the mitochondrial proteins; and that the precursors in the extramitochondrial pool differ in structure or conformation from the functional proteins in the mitochondria." @default.
• W2128908475 created "2016-06-24" @default.
• W2128908475 creator A5001578727 @default.
• W2128908475 creator A5021141200 @default.
• W2128908475 creator A5021964972 @default.
• W2128908475 creator A5046289240 @default.
• W2128908475 date "1977-12-01" @default.
• W2128908475 modified "2023-10-07" @default.
• W2128908475 title "Transport of Cytoplasmically Synthesized Proteins into the Mitochondria in a Cell Free System from Neurospora crassa" @default.
• W2128908475 cites W1481707322 @default.
• W2128908475 cites W1492147933 @default.
• W2128908475 cites W1522467031 @default.
• W2128908475 cites W1526598258 @default.
• W2128908475 cites W155340105 @default.
• W2128908475 cites W1565363013 @default.
• W2128908475 cites W1766236149 @default.
• W2128908475 cites W184953181 @default.
• W2128908475 cites W1967107400 @default.
• W2128908475 cites W1968783924 @default.
• W2128908475 cites W1970133894 @default.
• W2128908475 cites W1970581604 @default.
• W2128908475 cites W1976810253 @default.
• W2128908475 cites W2010219341 @default.
• W2128908475 cites W2012818879 @default.
• W2128908475 cites W2016235932 @default.
• W2128908475 cites W2019670695 @default.
• W2128908475 cites W2020352062 @default.
• W2128908475 cites W2029274340 @default.
• W2128908475 cites W2041276944 @default.
• W2128908475 cites W2051293837 @default.
• W2128908475 cites W2063667922 @default.
• W2128908475 cites W2076856886 @default.
• W2128908475 cites W2079856797 @default.
• W2128908475 cites W2083614040 @default.
• W2128908475 cites W2091343327 @default.
• W2128908475 cites W2100384124 @default.
• W2128908475 cites W2121484072 @default.
• W2128908475 cites W2131192895 @default.
• W2128908475 cites W2131756959 @default.
• W2128908475 cites W2146923243 @default.
• W2128908475 cites W2237903720 @default.
• W2128908475 cites W2946461375 @default.
• W2128908475 cites W32514773 @default.
• W2128908475 doi "https://doi.org/10.1111/j.1432-1033.1977.tb11979.x" @default.
• W2128908475 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/145943" @default.
• W2128908475 hasPublicationYear "1977" @default.
• W2128908475 type Work @default.
• W2128908475 sameAs 2128908475 @default.
• W2128908475 citedByCount "110" @default.
• W2128908475 countsByYear W21289084752012 @default.
• W2128908475 countsByYear W21289084752014 @default.
• W2128908475 countsByYear W21289084752015 @default.
• W2128908475 countsByYear W21289084752017 @default.
• W2128908475 countsByYear W21289084752018 @default.
• W2128908475 countsByYear W21289084752019 @default.
• W2128908475 countsByYear W21289084752020 @default.
• W2128908475 countsByYear W21289084752022 @default.
• W2128908475 countsByYear W21289084752023 @default.
• W2128908475 crossrefType "journal-article" @default.
• W2128908475 hasAuthorship W2128908475A5001578727 @default.
• W2128908475 hasAuthorship W2128908475A5021141200 @default.
• W2128908475 hasAuthorship W2128908475A5021964972 @default.
• W2128908475 hasAuthorship W2128908475A5046289240 @default.
• W2128908475 hasBestOaLocation W21289084752 @default.
• W2128908475 hasConcept C104317684 @default.
• W2128908475 hasConcept C143065580 @default.
• W2128908475 hasConcept C145488412 @default.
• W2128908475 hasConcept C146587185 @default.
• W2128908475 hasConcept C159382241 @default.
• W2128908475 hasConcept C181199279 @default.
• W2128908475 hasConcept C190062978 @default.
• W2128908475 hasConcept C2776739539 @default.
• W2128908475 hasConcept C2780090675 @default.
• W2128908475 hasConcept C28859421 @default.
• W2128908475 hasConcept C3675279 @default.
• W2128908475 hasConcept C547475151 @default.
• W2128908475 hasConcept C55493867 @default.
• W2128908475 hasConcept C67705224 @default.
• W2128908475 hasConcept C74897846 @default.
• W2128908475 hasConcept C75385678 @default.
• W2128908475 hasConcept C86803240 @default.
• W2128908475 hasConcept C88478588 @default.
• W2128908475 hasConcept C95444343 @default.
• W2128908475 hasConcept C98539663 @default.
• W2128908475 hasConceptScore W2128908475C104317684 @default.
• W2128908475 hasConceptScore W2128908475C143065580 @default.
• W2128908475 hasConceptScore W2128908475C145488412 @default.
• W2128908475 hasConceptScore W2128908475C146587185 @default.
• W2128908475 hasConceptScore W2128908475C159382241 @default.
• W2128908475 hasConceptScore W2128908475C181199279 @default.
• W2128908475 hasConceptScore W2128908475C190062978 @default.
• W2128908475 hasConceptScore W2128908475C2776739539 @default.
• W2128908475 hasConceptScore W2128908475C2780090675 @default.
• W2128908475 hasConceptScore W2128908475C28859421 @default.
• W2128908475 hasConceptScore W2128908475C3675279 @default.
• W2128908475 hasConceptScore W2128908475C547475151 @default.
• W2128908475 hasConceptScore W2128908475C55493867 @default.
• W2128908475 hasConceptScore W2128908475C67705224 @default.

• next