Matches in SemOpenAlex for { <https://semopenalex.org/work/W2128941915> ?p ?o ?g. }
- W2128941915 endingPage "202" @default.
- W2128941915 startingPage "192" @default.
- W2128941915 abstract "ABSTRACT Candida albicans contains a functional mating response pathway that is similar to the well-studied system of Saccharomyces cerevisiae . We have characterized a r egulator of G protein s ignaling (RGS) homolog in C. albicans with sequence similarity to the SST2 gene of Saccharomyces cerevisiae . Disruption of this gene, which had been designated SST2 , causes an opaque MTL a / MTL a derivative of strain SC5314 to show hypersensitivity to the C. albicans α-factor. This hypersensitivity generates an enhanced cell cycle arrest detected in halo assays but reduces the overall mating efficiency of the cells. Transcriptional profiling of the pheromone-regulated gene expression in the sst2 mutant shows a pattern of gene induction similar to that observed in wild-type cells, but the responsiveness is heightened. This involvement of an RGS in the sensitivity to pheromone is consistent with the prediction that the mating response pathway in C. albicans requires the activation of a heterotrimeric G protein." @default.
- W2128941915 created "2016-06-24" @default.
- W2128941915 creator A5059796808 @default.
- W2128941915 creator A5076154224 @default.
- W2128941915 date "2006-01-01" @default.
- W2128941915 modified "2023-09-29" @default.
- W2128941915 title "<i>SST2</i> , a Regulator of G-Protein Signaling for the <i>Candida albicans</i> Mating Response Pathway" @default.
- W2128941915 cites W1497947649 @default.
- W2128941915 cites W1509452146 @default.
- W2128941915 cites W1816698461 @default.
- W2128941915 cites W1934253322 @default.
- W2128941915 cites W1953744040 @default.
- W2128941915 cites W1977922844 @default.
- W2128941915 cites W1983183777 @default.
- W2128941915 cites W1995504351 @default.
- W2128941915 cites W2006018729 @default.
- W2128941915 cites W2006959076 @default.
- W2128941915 cites W2017277478 @default.
- W2128941915 cites W2022076650 @default.
- W2128941915 cites W2048411015 @default.
- W2128941915 cites W2049505636 @default.
- W2128941915 cites W2058482607 @default.
- W2128941915 cites W2060721894 @default.
- W2128941915 cites W2061091892 @default.
- W2128941915 cites W2065833639 @default.
- W2128941915 cites W2071242185 @default.
- W2128941915 cites W2084737875 @default.
- W2128941915 cites W2092975281 @default.
- W2128941915 cites W2095055516 @default.
- W2128941915 cites W2102021584 @default.
- W2128941915 cites W2112072577 @default.
- W2128941915 cites W2115464623 @default.
- W2128941915 cites W2118759693 @default.
- W2128941915 cites W2120191560 @default.
- W2128941915 cites W2126966227 @default.
- W2128941915 cites W2133083377 @default.
- W2128941915 cites W2135587043 @default.
- W2128941915 cites W2143325439 @default.
- W2128941915 cites W2152394730 @default.
- W2128941915 cites W2155458286 @default.
- W2128941915 cites W2156005120 @default.
- W2128941915 cites W2165827733 @default.
- W2128941915 cites W2167007363 @default.
- W2128941915 cites W3021509188 @default.
- W2128941915 cites W4239771041 @default.
- W2128941915 cites W4249761339 @default.
- W2128941915 doi "https://doi.org/10.1128/ec.5.1.192-202.2006" @default.
- W2128941915 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1360253" @default.
- W2128941915 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16400182" @default.
- W2128941915 hasPublicationYear "2006" @default.
- W2128941915 type Work @default.
- W2128941915 sameAs 2128941915 @default.
- W2128941915 citedByCount "34" @default.
- W2128941915 countsByYear W21289419152012 @default.
- W2128941915 countsByYear W21289419152013 @default.
- W2128941915 countsByYear W21289419152014 @default.
- W2128941915 countsByYear W21289419152016 @default.
- W2128941915 countsByYear W21289419152017 @default.
- W2128941915 countsByYear W21289419152019 @default.
- W2128941915 countsByYear W21289419152021 @default.
- W2128941915 crossrefType "journal-article" @default.
- W2128941915 hasAuthorship W2128941915A5059796808 @default.
- W2128941915 hasAuthorship W2128941915A5076154224 @default.
- W2128941915 hasBestOaLocation W21289419151 @default.
- W2128941915 hasConcept C104317684 @default.
- W2128941915 hasConcept C139407321 @default.
- W2128941915 hasConcept C143065580 @default.
- W2128941915 hasConcept C145081991 @default.
- W2128941915 hasConcept C2777576037 @default.
- W2128941915 hasConcept C2780917455 @default.
- W2128941915 hasConcept C2910135453 @default.
- W2128941915 hasConcept C54355233 @default.
- W2128941915 hasConcept C62478195 @default.
- W2128941915 hasConcept C80631254 @default.
- W2128941915 hasConcept C86803240 @default.
- W2128941915 hasConcept C95444343 @default.
- W2128941915 hasConceptScore W2128941915C104317684 @default.
- W2128941915 hasConceptScore W2128941915C139407321 @default.
- W2128941915 hasConceptScore W2128941915C143065580 @default.
- W2128941915 hasConceptScore W2128941915C145081991 @default.
- W2128941915 hasConceptScore W2128941915C2777576037 @default.
- W2128941915 hasConceptScore W2128941915C2780917455 @default.
- W2128941915 hasConceptScore W2128941915C2910135453 @default.
- W2128941915 hasConceptScore W2128941915C54355233 @default.
- W2128941915 hasConceptScore W2128941915C62478195 @default.
- W2128941915 hasConceptScore W2128941915C80631254 @default.
- W2128941915 hasConceptScore W2128941915C86803240 @default.
- W2128941915 hasConceptScore W2128941915C95444343 @default.
- W2128941915 hasIssue "1" @default.
- W2128941915 hasLocation W21289419151 @default.
- W2128941915 hasLocation W21289419152 @default.
- W2128941915 hasLocation W21289419153 @default.
- W2128941915 hasLocation W21289419154 @default.
- W2128941915 hasOpenAccess W2128941915 @default.
- W2128941915 hasPrimaryLocation W21289419151 @default.
- W2128941915 hasRelatedWork W1967435582 @default.
- W2128941915 hasRelatedWork W1976497700 @default.
- W2128941915 hasRelatedWork W2039261716 @default.