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- W2128966773 abstract "The induction of sister-chromatid exchange (SCE) by a photoactivated monofunctional derivative of psoralen, 3-carbethoxypsoralen (3-CPs) was compared with that of the bifunctional compound, 8-methoxypsoralen (8-MOP). Lymphocytes were exposed in vitro to a series of equimolar concentrations of the drugs as well as to increasing doses of long-wave ultraviolet high (UVA) and second-division metaphases examined for SCE. The drugs or UVA per se did not influence the incidence of SCE. However, combination of the drug and UVA exposure resulted in a dose-dependent increase in SCE and such elevation was less pronounced with 3-CPs as compared to 8-MOP. This difference between 3-CPs and 8-MOP could be due to difference in the types of lesions induced/repaired in DNA." @default.
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- W2128966773 title "Comparison of sister-chromatid exchange induced by photoactivated 3-carbethoxypsoralen and 8-methoxypsoralen in human blood lymphocytes" @default.
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- W2128966773 doi "https://doi.org/10.1016/0027-5107(85)90063-6" @default.
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