FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2129049245> ?p ?o ?g. }

• W2129049245 endingPage "401" @default.
• W2129049245 startingPage "395" @default.
• W2129049245 abstract "In some geographic areas birch pollen represents the most prominent cause for airborne allergic diseases. Up to 70% of patients allergic to birch pollen are hypersensitive to fruits, especially apples. Associations have been found, in some instances, with a sensitivity to aeroallergens and HLA class II genes.We investigated whether susceptibility or resistance to birch pollen allergy with and without food allergy was associated with HLA class II genes.Blood samples were obtained from 2 groups of unrelated European-born white adults: 42 atopic patients (31 of them with asthma) and 42 healthy control subjects with no personal or familial history of asthma or atopy. Their antibody responses to birch pollen, apples, grass, and weed pollens were evaluated by skin tests, RASTs, and immunoprints. Genomic DNA was extracted from PBLs. The exons of DQA1, DQB1, DRB1, and DPB1 genes were selectively amplified by using the PCR method. Genotyping was carried out by digestion of the amplified DNA products with allele-specific endonucleases (PCR-RFLP), which recognize allelic variations in the polymorphic exon.We found no significant differences in the frequency of DPB1 alleles between patients and control subjects. HLA class II DR4 and/or DR7 alleles were present in 42.6% of the patients and in only 2.4% of the healthy subjects. These results confirm a previous study of a group of polysensitized atopic patients, which showed that DR4 and DR7 alleles were rare in healthy control subjects and frequently observed in atopic subjects with or without concomitant asthma.We conclude that the allele HLA-DR7 is significantly involved in the presentation of apple and pollen allergens. However, we suggest that this susceptibility is more related to atopy than to specific responses to allergens." @default.
• W2129049245 created "2016-06-24" @default.
• W2129049245 creator A5010747909 @default.
• W2129049245 creator A5015956099 @default.
• W2129049245 creator A5024419542 @default.
• W2129049245 creator A5027992755 @default.
• W2129049245 creator A5029926723 @default.
• W2129049245 creator A5037910933 @default.
• W2129049245 creator A5054661531 @default.
• W2129049245 creator A5064789042 @default.
• W2129049245 creator A5082432280 @default.
• W2129049245 creator A5086254885 @default.
• W2129049245 creator A5090155882 @default.
• W2129049245 date "1999-08-01" @default.
• W2129049245 modified "2023-10-18" @default.
• W2129049245 title "Genetics and specific immune response in allergy to birch pollen and food: Evidence of a strong, positive association between atopy and the HLA class II allele HLA-DR7☆☆☆★" @default.
• W2129049245 cites W1489756602 @default.
• W2129049245 cites W1970152749 @default.
• W2129049245 cites W1975449550 @default.
• W2129049245 cites W1979759634 @default.
• W2129049245 cites W1999719815 @default.
• W2129049245 cites W2002169500 @default.
• W2129049245 cites W2007254298 @default.
• W2129049245 cites W2019971246 @default.
• W2129049245 cites W2020940152 @default.
• W2129049245 cites W2022753715 @default.
• W2129049245 cites W2030956435 @default.
• W2129049245 cites W2049465161 @default.
• W2129049245 cites W2051548814 @default.
• W2129049245 cites W2060320117 @default.
• W2129049245 cites W2076003470 @default.
• W2129049245 cites W2076096345 @default.
• W2129049245 cites W2084523785 @default.
• W2129049245 cites W2084636378 @default.
• W2129049245 cites W2089339054 @default.
• W2129049245 cites W2090993494 @default.
• W2129049245 cites W2093118239 @default.
• W2129049245 cites W2104289972 @default.
• W2129049245 cites W2170165964 @default.
• W2129049245 cites W2414580871 @default.
• W2129049245 cites W2416821939 @default.
• W2129049245 doi "https://doi.org/10.1016/s0091-6749(99)70384-2" @default.
• W2129049245 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10452762" @default.
• W2129049245 hasPublicationYear "1999" @default.
• W2129049245 type Work @default.
• W2129049245 sameAs 2129049245 @default.
• W2129049245 citedByCount "37" @default.
• W2129049245 countsByYear W21290492452012 @default.
• W2129049245 countsByYear W21290492452013 @default.
• W2129049245 countsByYear W21290492452014 @default.
• W2129049245 countsByYear W21290492452015 @default.
• W2129049245 countsByYear W21290492452016 @default.
• W2129049245 countsByYear W21290492452019 @default.
• W2129049245 countsByYear W21290492452021 @default.
• W2129049245 crossrefType "journal-article" @default.
• W2129049245 hasAuthorship W2129049245A5010747909 @default.
• W2129049245 hasAuthorship W2129049245A5015956099 @default.
• W2129049245 hasAuthorship W2129049245A5024419542 @default.
• W2129049245 hasAuthorship W2129049245A5027992755 @default.
• W2129049245 hasAuthorship W2129049245A5029926723 @default.
• W2129049245 hasAuthorship W2129049245A5037910933 @default.
• W2129049245 hasAuthorship W2129049245A5054661531 @default.
• W2129049245 hasAuthorship W2129049245A5064789042 @default.
• W2129049245 hasAuthorship W2129049245A5082432280 @default.
• W2129049245 hasAuthorship W2129049245A5086254885 @default.
• W2129049245 hasAuthorship W2129049245A5090155882 @default.
• W2129049245 hasBestOaLocation W21290492451 @default.
• W2129049245 hasConcept C104317684 @default.
• W2129049245 hasConcept C135763542 @default.
• W2129049245 hasConcept C147483822 @default.
• W2129049245 hasConcept C180754005 @default.
• W2129049245 hasConcept C188280979 @default.
• W2129049245 hasConcept C203014093 @default.
• W2129049245 hasConcept C207480886 @default.
• W2129049245 hasConcept C2776042228 @default.
• W2129049245 hasConcept C2777697326 @default.
• W2129049245 hasConcept C31467283 @default.
• W2129049245 hasConcept C54355233 @default.
• W2129049245 hasConcept C86803240 @default.
• W2129049245 hasConceptScore W2129049245C104317684 @default.
• W2129049245 hasConceptScore W2129049245C135763542 @default.
• W2129049245 hasConceptScore W2129049245C147483822 @default.
• W2129049245 hasConceptScore W2129049245C180754005 @default.
• W2129049245 hasConceptScore W2129049245C188280979 @default.
• W2129049245 hasConceptScore W2129049245C203014093 @default.
• W2129049245 hasConceptScore W2129049245C207480886 @default.
• W2129049245 hasConceptScore W2129049245C2776042228 @default.
• W2129049245 hasConceptScore W2129049245C2777697326 @default.
• W2129049245 hasConceptScore W2129049245C31467283 @default.
• W2129049245 hasConceptScore W2129049245C54355233 @default.
• W2129049245 hasConceptScore W2129049245C86803240 @default.
• W2129049245 hasIssue "2" @default.
• W2129049245 hasLocation W21290492451 @default.
• W2129049245 hasLocation W21290492452 @default.
• W2129049245 hasOpenAccess W2129049245 @default.
• W2129049245 hasPrimaryLocation W21290492451 @default.
• W2129049245 hasRelatedWork W121700474 @default.
• W2129049245 hasRelatedWork W1964534404 @default.

• next