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- W2129058266 abstract "Outer membrane vesicles (OMVs) shed from the gastroduodenal pathogen Helicobacter pylori have measurable effects on epithelial cell responses. The aim of this study was to determine the effect of iron availability, and its basis, on the extent and nature of lipopolysaccharide (LPS) produced on H. pylori OMVs and their parental bacterial cells. Electrophoretic, immunoblotting and structural analyses revealed that LPSs of bacterial cells grown under iron-limited conditions were notably shorter than those of bacteria and OMVs obtained from iron-replete conditions. Structural analysis and serological probing showed that LPSs of iron-replete cells and OMVs expressed O-chains of Lewis(x) with a terminal Lewis(y) unit, whereas Lewis(y) expression was notably reduced on bacteria and OMVs from iron-limiting conditions. Unlike the O-chain, the core oligosaccharide and lipid A moieties of iron-replete and iron-limited bacteria and their OMVs were similar. Quantitatively, shed OMVs from iron-replete bacteria were found to be LPSenriched, whereas shed OMVs from iron-limited bacteria had a significantly reduced content of LPS. These differences were linked to bacterial ATP levels. Since iron availability affects the extent and nature of LPS expressed by H. pylori, host iron status may contribute to H. pylori pathogenesis." @default.
- W2129058266 created "2016-06-24" @default.
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- W2129058266 date "2008-10-01" @default.
- W2129058266 modified "2023-10-16" @default.
- W2129058266 title "Alterations in <i>Helicobacter pylori</i> outer membrane and outer membrane vesicle-associated lipopolysaccharides under iron-limiting growth conditions*" @default.
- W2129058266 cites W1534051479 @default.
- W2129058266 cites W1553166933 @default.
- W2129058266 cites W1621166403 @default.
- W2129058266 cites W1630752783 @default.
- W2129058266 cites W1788623016 @default.
- W2129058266 cites W1796772814 @default.
- W2129058266 cites W1904576076 @default.
- W2129058266 cites W1922098314 @default.
- W2129058266 cites W1933982026 @default.
- W2129058266 cites W1957957211 @default.
- W2129058266 cites W1971976758 @default.
- W2129058266 cites W1972370790 @default.
- W2129058266 cites W1973232347 @default.
- W2129058266 cites W1976119740 @default.
- W2129058266 cites W1976955035 @default.
- W2129058266 cites W1984367265 @default.
- W2129058266 cites W1989107717 @default.
- W2129058266 cites W1997969528 @default.
- W2129058266 cites W1999085787 @default.
- W2129058266 cites W2019625246 @default.
- W2129058266 cites W2030680491 @default.
- W2129058266 cites W2031423487 @default.
- W2129058266 cites W2036579054 @default.
- W2129058266 cites W2041053334 @default.
- W2129058266 cites W2044025776 @default.
- W2129058266 cites W2049732161 @default.
- W2129058266 cites W2059784037 @default.
- W2129058266 cites W2064697520 @default.
- W2129058266 cites W2076030198 @default.
- W2129058266 cites W2083520311 @default.
- W2129058266 cites W2084701457 @default.
- W2129058266 cites W2085837952 @default.
- W2129058266 cites W2088785425 @default.
- W2129058266 cites W2088902653 @default.
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- W2129058266 cites W2097382368 @default.
- W2129058266 cites W2105424869 @default.
- W2129058266 cites W2106842097 @default.
- W2129058266 cites W2107285671 @default.
- W2129058266 cites W2110132014 @default.
- W2129058266 cites W2110827592 @default.
- W2129058266 cites W2111345507 @default.
- W2129058266 cites W2112387002 @default.
- W2129058266 cites W2116073794 @default.
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- W2129058266 cites W2123779740 @default.
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- W2129058266 cites W2127573420 @default.
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- W2129058266 cites W2131939332 @default.
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- W2129058266 doi "https://doi.org/10.1177/1753425908096857" @default.
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