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- W2129060055 abstract "Significance Plant biomass conversion into biofuels and chemicals can reduce human reliance on petroleum and promote sustainable biorefining processes. The structural polymer lignin can comprise up to 40% of plant biomass, but resists decomposition into valuable monoaromatic compounds. In this study, we devised a previously unidentified biosensor responsive to lignin transformation products. We used this biosensor in a functional screen to recover metagenomic scaffolds sourced from coal bed bacterial communities. Genetic and biochemical analyses revealed six functional classes mediating lignin transformation that are mobilized in nature via horizontal gene transfer. Our results suggest that bacterial lignin transformation is an adaptive trait that can be exploited to engineer combinatorial arrays with defined product profiles, a prerequisite for scale-up production using different plant sources." @default.
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- W2129060055 date "2014-06-30" @default.
- W2129060055 modified "2023-10-10" @default.
- W2129060055 title "Metagenomic scaffolds enable combinatorial lignin transformation" @default.
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- W2129060055 doi "https://doi.org/10.1073/pnas.1401631111" @default.
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