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- W2129086964 abstract "A prospective 2-year clinical and macro-EMG follow up was completed in 30 post-polio survivors (19 women and 11 men, aged from 46 to 62 years). The median macro-MUPs amplitudes from either biceps brachii or tibial anterior muscles were estimated. A decrease in muscle strength > 1 MRC grade in the tested extremity was found in five patients (fulfilling criteria for progressive post-polio muscle atrophy-PPMA), and 17 post-polio patients complained of new weakness (Including five PPMA subjects). In seven healthy volunteers the changes in the median macro-MUPs amplitudes on serial examination varied from −18.8 to +22.4%. In 13 clinically stable patients the change in macro-MUPs amplitude over 2 years did not exceed 25% of the initial value, in comparison with nine of 17 patients with new complaints displaying a > 25% change in the macro-MUPs amplitude, with predominant decrease (6 of 9). All five PPMA patients showed a >25% change in the macro-MUPs amplitude with predominant decrease (+ 33, −27, −42, −50 and −60%). There was a statistically significant difference in the change of the median macro-MUPs amplitudes between PPMA group (n − 5) and post-polio patients without objective decline in muscle strength (n = 25; p < 0.05; the Mann–Whitney U test). These findings support the hypothesis of the distal degeneration of abnormally enlarged motor units as a cause of PPMA and show the usefulness of serial measurement in the assessment of PPMA." @default.
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- W2129086964 date "1996-03-01" @default.
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- W2129086964 title "Macroelectromyography in progressive post-polio muscular atrophy" @default.
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- W2129086964 doi "https://doi.org/10.1111/j.1468-1331.1996.tb00202.x" @default.
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