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- W2129093006 abstract "Gas chromatography/mass spectrometry (GC/MS) is a widely used analytic tool for qualitative and quantitative analysis of volatile and semi-volatile compounds. However, GC/MS use is limited by its large size, lack of portability, high cost and inherent complexity. Smaller instruments capable of high-throughput analysis of volatile compounds have the potential of combining MS-like sensitivity with portability. The micromachined differential mobility spectrometer (DMS) is a miniature sensor capable of registering volatile compounds in sub-parts-per-million (ppm) concentrations. It is small, portable, and can be coupled with multiple other compound separation methods. Here we describe paired volatile sample analyses using both GC/MS and GC/DMS which show that the DMS is capable of registering known compounds as verified by MS. Furthermore, we show that MS can be used to help build a library for our unique DMS sensor outputs and detect compounds in chemically complex backgrounds." @default.
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- W2129093006 date "2011-06-30" @default.
- W2129093006 modified "2023-09-25" @default.
- W2129093006 title "Building biomarker libraries with novel chemical sensors: correlating differential mobility spectrometer signal outputs with mass spectrometry data" @default.
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- W2129093006 doi "https://doi.org/10.1088/1757-899x/18/21/212003" @default.
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