FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2129122279> ?p ?o ?g. }

• W2129122279 endingPage "290" @default.
• W2129122279 startingPage "284" @default.
• W2129122279 abstract "There is increasing interest in the extraskeletal effects of vitamin D, particularly in the obese state with regard to the development of insulin resistance and diabetes.The objective of the study was to determine the effect of 2 doses of cholecalciferol (vitamin D3) supplementation on insulin action (Si) and pancreatic β-cell function in obese adolescents.We performed a 12-wk double-blind, randomized comparison of the effect of vitamin D3 supplementation on Si and β-cell function in obese Caucasian adolescents (body mass index > 95(th) percentile). The subjects were randomly assigned to receive either 400 IU/d (n = 25) or 2000 IU/d (n = 26) of vitamin D3. Each subject underwent a 7-sample 75 g oral glucose tolerance test, with glucose, insulin, and C-peptide measurements, to calculate Si and β-cell function as assessed by the disposition index (DI), with use of the oral minimal model before and after supplementation. A total of 51 subjects aged 15.0 ± 1.9 y were enrolled. Included for analysis at follow-up were a total of 46 subjects (20 male and 26 female adolescents), 23 in each group.Initial serum 25-hydroxyvitamin D [25(OH)D] was 24.0 ± 8.1 μg/L. There was no correlation between 25(OH)D concentrations and Si or DI. There was a modest but significant increase in 25(OH)D concentration in the 2000 IU/d group (3.1 ± 6.5 μg/L, P = 0.04) but not in the 400 IU/d group (P = 0.39). There was no change in Si or DI following vitamin D3 supplementation in either of the treatment groups (all P > 0.10).The current study shows no effect from vitamin D3 supplementation, irrespective of its dose, on β-cell function or insulin action in obese nondiabetic adolescents with relatively good vitamin D status. Whether obese adolescents with vitamin D deficiency and impaired glucose metabolism would respond differently to vitamin D3 supplementation remains unclear and warrants further studies. This trial was registered at clinicaltrials.gov as NCT00858247." @default.
• W2129122279 created "2016-06-24" @default.
• W2129122279 creator A5010282758 @default.
• W2129122279 creator A5013986317 @default.
• W2129122279 creator A5026228486 @default.
• W2129122279 creator A5030751618 @default.
• W2129122279 creator A5034412938 @default.
• W2129122279 creator A5035024612 @default.
• W2129122279 creator A5038127563 @default.
• W2129122279 creator A5040049035 @default.
• W2129122279 creator A5060981762 @default.
• W2129122279 creator A5068823308 @default.
• W2129122279 creator A5091104216 @default.
• W2129122279 date "2015-02-01" @default.
• W2129122279 modified "2023-10-17" @default.
• W2129122279 title "Cholecalciferol Supplementation Does Not Influence β-Cell Function and Insulin Action in Obese Adolescents: A Prospective Double-Blind Randomized Trial," @default.
• W2129122279 cites W1583951223 @default.
• W2129122279 cites W1943509371 @default.
• W2129122279 cites W1967469266 @default.
• W2129122279 cites W1968111450 @default.
• W2129122279 cites W1968174416 @default.
• W2129122279 cites W1978340695 @default.
• W2129122279 cites W1985978903 @default.
• W2129122279 cites W1996853424 @default.
• W2129122279 cites W1997582920 @default.
• W2129122279 cites W2007000025 @default.
• W2129122279 cites W2018459966 @default.
• W2129122279 cites W2019558876 @default.
• W2129122279 cites W2026437158 @default.
• W2129122279 cites W2029000123 @default.
• W2129122279 cites W2050624701 @default.
• W2129122279 cites W2057089785 @default.
• W2129122279 cites W2058304145 @default.
• W2129122279 cites W2061256393 @default.
• W2129122279 cites W2063500645 @default.
• W2129122279 cites W2066112500 @default.
• W2129122279 cites W2067732121 @default.
• W2129122279 cites W2070231213 @default.
• W2129122279 cites W2072787277 @default.
• W2129122279 cites W2083809911 @default.
• W2129122279 cites W2107065593 @default.
• W2129122279 cites W2110765297 @default.
• W2129122279 cites W2113594895 @default.
• W2129122279 cites W2113657076 @default.
• W2129122279 cites W2115326572 @default.
• W2129122279 cites W2118264213 @default.
• W2129122279 cites W2123229781 @default.
• W2129122279 cites W2124070987 @default.
• W2129122279 cites W2126545477 @default.
• W2129122279 cites W2131909681 @default.
• W2129122279 cites W2134433004 @default.
• W2129122279 cites W2146848765 @default.
• W2129122279 cites W2149409837 @default.
• W2129122279 cites W2157304718 @default.
• W2129122279 cites W2158158671 @default.
• W2129122279 cites W2159465039 @default.
• W2129122279 cites W2160146305 @default.
• W2129122279 cites W2163984033 @default.
• W2129122279 cites W2172006441 @default.
• W2129122279 cites W2312070181 @default.
• W2129122279 cites W4253280909 @default.
• W2129122279 doi "https://doi.org/10.3945/jn.114.202010" @default.
• W2129122279 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6619681" @default.
• W2129122279 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25644349" @default.
• W2129122279 hasPublicationYear "2015" @default.
• W2129122279 type Work @default.
• W2129122279 sameAs 2129122279 @default.
• W2129122279 citedByCount "36" @default.
• W2129122279 countsByYear W21291222792015 @default.
• W2129122279 countsByYear W21291222792016 @default.
• W2129122279 countsByYear W21291222792017 @default.
• W2129122279 countsByYear W21291222792018 @default.
• W2129122279 countsByYear W21291222792019 @default.
• W2129122279 countsByYear W21291222792020 @default.
• W2129122279 countsByYear W21291222792021 @default.
• W2129122279 countsByYear W21291222792022 @default.
• W2129122279 countsByYear W21291222792023 @default.
• W2129122279 crossrefType "journal-article" @default.
• W2129122279 hasAuthorship W2129122279A5010282758 @default.
• W2129122279 hasAuthorship W2129122279A5013986317 @default.
• W2129122279 hasAuthorship W2129122279A5026228486 @default.
• W2129122279 hasAuthorship W2129122279A5030751618 @default.
• W2129122279 hasAuthorship W2129122279A5034412938 @default.
• W2129122279 hasAuthorship W2129122279A5035024612 @default.
• W2129122279 hasAuthorship W2129122279A5038127563 @default.
• W2129122279 hasAuthorship W2129122279A5040049035 @default.
• W2129122279 hasAuthorship W2129122279A5060981762 @default.
• W2129122279 hasAuthorship W2129122279A5068823308 @default.
• W2129122279 hasAuthorship W2129122279A5091104216 @default.
• W2129122279 hasBestOaLocation W21291222791 @default.
• W2129122279 hasConcept C124490489 @default.
• W2129122279 hasConcept C126322002 @default.
• W2129122279 hasConcept C134018914 @default.
• W2129122279 hasConcept C2776940978 @default.
• W2129122279 hasConcept C2777391703 @default.
• W2129122279 hasConcept C2779306644 @default.
• W2129122279 hasConcept C2779740938 @default.
• W2129122279 hasConcept C2780106736 @default.

• next