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- W2129129940 endingPage "841" @default.
- W2129129940 startingPage "831" @default.
- W2129129940 abstract "Viral-associated malignancies usually arise in the setting of altered immunity or with declines in immune function associated with aging. The main culprits are the lymphotropic herpesvirus, including Epstein-Barr virus (EBV) and human herpesvirus-8, which are the focus of this review. Chronic persistent infection and viral reactivation are the main risk factors for development of herpesvirus-associated malignancies and have provided the rationale for intensive monitoring of viral loads in some clinical contexts. Quantitative detection of EBV levels in the post-transplant period and following treatment of EBV-associated malignancies now have a proven role in outcome prediction. Both T-cell immunotherapy and humoral immunotherapies directed against latent viral antigens represent promising interventional approaches to treatment of viral-associated malignancies." @default.
- W2129129940 created "2016-06-24" @default.
- W2129129940 creator A5006583715 @default.
- W2129129940 creator A5070451207 @default.
- W2129129940 date "2006-11-01" @default.
- W2129129940 modified "2023-09-25" @default.
- W2129129940 title "Molecular approaches towards characterization, monitoring and targeting of viral-associated hematological malignancies" @default.
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